STRINGSTRING
ALDH1A1 ALDH1A1 ZC3H12A ZC3H12A GREB1 GREB1 CREB1 CREB1 NRIP1 NRIP1 PDHA2 PDHA2 POLR2H POLR2H EEPD1 EEPD1 POLR2E POLR2E KDM4B KDM4B GNAI1 GNAI1 TBP TBP GNAI2 GNAI2 LOC111556172 LOC111556172 HDAC3 HDAC3 RUNX1 RUNX1 CREBBP CREBBP PTGES3 PTGES3 CPT1C CPT1C RDH13 RDH13 SPHK1 SPHK1 DHRS13 DHRS13 EP300 EP300 AKT1 AKT1 CARM1 CARM1 DLD DLD KAT2B KAT2B ABCA1 ABCA1 NXNL2 NXNL2 M3W104_FELCA M3W104_FELCA AKT3 AKT3 DDX5 DDX5 HRAS HRAS XPO1 XPO1 TBL1XR1 TBL1XR1 PDHB PDHB GTF2F2 GTF2F2 PDPK1 PDPK1 POLR2K POLR2K MYB MYB ALDH8A1 ALDH8A1 SHC1 SHC1 HBEGF HBEGF STRN4 STRN4 DHRS3 DHRS3 AREG AREG SLC29A1 SLC29A1 ENSFCAP00000061275 ENSFCAP00000061275 RDH11 RDH11 LOC101092762 LOC101092762 ERAS ERAS LOC101089514 LOC101089514 USF2 USF2 CPT1A CPT1A H2BC5 H2BC5 FABP5 FABP5 ADH4 ADH4 ENSFCAP00000054404 ENSFCAP00000054404 H2AX H2AX PRKCZ PRKCZ EBAG9 EBAG9 CALM3 CALM3 YY1 YY1 LOC101089767 LOC101089767 ARL4A ARL4A AKR1C3 AKR1C3 USF1 USF1 ENSFCAP00000057069 ENSFCAP00000057069 LOC101098145 LOC101098145 ZNF217 ZNF217 LOC101082235-7 LOC101082235-7 ZC3H12C ZC3H12C ELK1 ELK1 ENSFCAP00000058404 ENSFCAP00000058404 LOC101083921 LOC101083921 GNG2 GNG2 ENSFCAP00000059504 ENSFCAP00000059504 GNB5 GNB5 UHMK1 UHMK1 AKT2 AKT2 KANK3 KANK3 EGF EGF ENSFCAP00000060347 ENSFCAP00000060347 KANK1 KANK1 CRABP2 CRABP2 H2BE1 H2BE1 GNG4 GNG4 NR1H3 NR1H3 ZFP42 ZFP42 LOC101082235-6 LOC101082235-6 RARG RARG ENSFCAP00000051025 ENSFCAP00000051025 LOC101087478 LOC101087478 H2BC3 H2BC3 GNG10 GNG10 CALM1 CALM1 POLR2L POLR2L LOC101086971 LOC101086971 STRN STRN POLR2B POLR2B PGR PGR LOC101082235-5 LOC101082235-5 RXRA RXRA LOC101082235-4 LOC101082235-4 LOC101084959 LOC101084959 LOC101080632 LOC101080632 LOC105260541-3 LOC105260541-3 LOC101095347-4 LOC101095347-4 GTF2A2 GTF2A2 ENSFCAP00000048881 ENSFCAP00000048881 LOC101088485 LOC101088485 LOC101080886 LOC101080886 LOC101084708 LOC101084708 GNG8 GNG8 LOC105260541-2 LOC105260541-2 CCNT1 CCNT1 LOC101082235-3 LOC101082235-3 POLR2F POLR2F LOC101083933 LOC101083933 GNG12 GNG12 JUND JUND PIK3R3 PIK3R3 LOC101095347-3 LOC101095347-3 FOS FOS LOC101088237 LOC101088237 ENSFCAP00000045932 ENSFCAP00000045932 PLIN1 PLIN1 LOC101082235-2 LOC101082235-2 CBFB CBFB LOC101082491 LOC101082491 LOC101100603 LOC101100603 LOC101093269 LOC101093269 LOC101095347-2 LOC101095347-2 MED1 MED1 LOC101084193 LOC101084193 GATA3 GATA3 H3C13 H3C13 ENSFCAP00000043900 ENSFCAP00000043900 LOC101085801 LOC101085801 PIK3R2 PIK3R2 ENSFCAP00000043372 ENSFCAP00000043372 PDK3 PDK3 ESR2 ESR2 ENSFCAP00000042498 ENSFCAP00000042498 ERBB4 ERBB4 LOC101095347 LOC101095347 NCOA1 NCOA1 ALDH1A2 ALDH1A2 ENSFCAP00000041747 ENSFCAP00000041747 HSP90AA1 HSP90AA1 EGFR EGFR SRC SRC LOC105260541 LOC105260541 TBL1X TBL1X HIST2H3C HIST2H3C TGFA TGFA LOC101082235 LOC101082235 GREB1L GREB1L KAT5 KAT5 EPGN EPGN MMP2 MMP2 H2AZ2 H2AZ2 GNG5 GNG5 ENSFCAP00000039174 ENSFCAP00000039174 CHRNB1 CHRNB1 GTF2A1 GTF2A1 PIK3CA PIK3CA KANK2 KANK2 POLR2C POLR2C ENSFCAP00000036538 ENSFCAP00000036538 CEP170 CEP170 TBPL1 TBPL1 RARA RARA DHRS2 DHRS2 NRAS NRAS PTK2 PTK2 BTC BTC GNG3 GNG3 NCOR1 NCOR1 HDAC1 HDAC1 TRPS1 TRPS1 PRMT8 PRMT8 CITED1 CITED1 DHRS9 DHRS9 TBPL2 TBPL2 ZC3H12B ZC3H12B FKBP4 FKBP4 ENSFCAP00000030326 ENSFCAP00000030326 CAV1 CAV1 ENSFCAP00000029012 ENSFCAP00000029012 ENSFCAP00000028809 ENSFCAP00000028809 LOC101097703 LOC101097703 CDK9 CDK9 CPT1B CPT1B SRBD1 SRBD1 PRMT1 PRMT1 ENSFCAP00000028340 ENSFCAP00000028340 GNAI3 GNAI3 CALML3 CALML3 POLR2J POLR2J LOC109498222 LOC109498222 ENSFCAP00000027305 ENSFCAP00000027305 PPARD PPARD GNGT2 GNGT2 GNG11 GNG11 ZDHHC21 ZDHHC21 GNB4 GNB4 LOC101087401 LOC101087401 ENSFCAP00000026553 ENSFCAP00000026553 GNAT3 GNAT3 ARL4C ARL4C ENSFCAP00000025898 ENSFCAP00000025898 MAPK1 MAPK1 PDK1 PDK1 M3XDD6_FELCA M3XDD6_FELCA CHD1 CHD1 GPS2 GPS2 NCOR2 NCOR2 DHRSX DHRSX LOC101097798 LOC101097798 POLR2I POLR2I FOXO3 FOXO3 POLR2G POLR2G LOC101092488 LOC101092488 GNG14 GNG14 GNB2 GNB2 LOC101100387 LOC101100387 ZDHHC7 ZDHHC7 FOSB FOSB LOC101088423 LOC101088423 PPID PPID FOXA1 FOXA1 KANK4 KANK4 CSDE1 CSDE1 ESR1 ESR1 GTF2A1L GTF2A1L H2BU1 H2BU1 H3F3A H3F3A FKBP5 FKBP5 LOC101096314 LOC101096314 M3WZ36_FELCA M3WZ36_FELCA UPK3BL2 UPK3BL2 CAV2 CAV2 NCOA2 NCOA2 HSPB1 HSPB1 RDH10 RDH10 EREG EREG GNGT1 GNGT1 POLR2D POLR2D GNB1 GNB1 PDK4 PDK4 PDHX PDHX M3WQU5_FELCA M3WQU5_FELCA TFF3 TFF3 CALM2 CALM2 SP1 SP1 M3WPU0_FELCA M3WPU0_FELCA IGF1R IGF1R KRAS KRAS MMP3 MMP3 MMP7 MMP7 DLAT DLAT NCOA3 NCOA3 SDR16C5 SDR16C5 H2BC1 H2BC1 RDH16 RDH16 PPP5C PPP5C RDH5 RDH5 KDM1A KDM1A STRN3 STRN3 WDR64 WDR64 NOS3 NOS3 PDHA1 PDHA1 GTF2F1 GTF2F1 GNB3 GNB3 PIK3R1 PIK3R1 RXRG RXRG ALDH1A3 ALDH1A3 CXXC5 CXXC5 CRABP1 CRABP1 RARB RARB GNG13 GNG13 CYP26C1 CYP26C1 PDK2 PDK2 NR1H2 NR1H2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ALDH1A1Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family. (501 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (582 aa)
GREB1Growth regulating estrogen receptor binding 1. (1943 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
NRIP1Nuclear receptor interacting protein 1. (1155 aa)
PDHA2Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (391 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
EEPD1Endonuclease/exonuclease/phosphatase family domain containing 1. (569 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
KDM4BLysine demethylase 4B. (1124 aa)
GNAI1G protein subunit alpha i1. (354 aa)
TBPTATA-box binding protein. (327 aa)
GNAI2G protein subunit alpha i2. (436 aa)
LOC111556172Uncharacterized protein. (536 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (493 aa)
CREBBPCREB binding protein. (2444 aa)
PTGES3Prostaglandin E synthase 3. (164 aa)
CPT1CCarnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (803 aa)
RDH13Retinol dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (331 aa)
SPHK1Sphingosine kinase 1. (473 aa)
DHRS13Dehydrogenase/reductase 13. (374 aa)
EP300E1A binding protein p300. (2425 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
CARM1Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (608 aa)
DLDDihydrolipoyl dehydrogenase. (509 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (834 aa)
ABCA1ATP binding cassette subfamily A member 1. (2261 aa)
NXNL2Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (623 aa)
M3W104_FELCAHistone domain-containing protein; Belongs to the histone H2B family. (88 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
XPO1Exportin 1. (1071 aa)
TBL1XR1WD_REPEATS_REGION domain-containing protein. (534 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (558 aa)
POLR2KUncharacterized protein. (58 aa)
MYBMYB proto-oncogene, transcription factor. (761 aa)
ALDH8A1Aldehyde dehydrogenase 8 family member A1; Belongs to the aldehyde dehydrogenase family. (518 aa)
SHC1SHC adaptor protein 1. (566 aa)
HBEGFHeparin binding EGF like growth factor. (305 aa)
STRN4Striatin 4. (817 aa)
DHRS3Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
AREGAmphiregulin. (323 aa)
SLC29A1Heat shock protein 90 alpha family class B member 1. (740 aa)
ENSFCAP00000061275Uncharacterized protein. (97 aa)
RDH11Retinol dehydrogenase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (426 aa)
LOC101092762Histone H4. (103 aa)
ERASES cell expressed Ras. (233 aa)
LOC101089514Histone H3.1. (136 aa)
USF2Upstream transcription factor 2, c-fos interacting. (367 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
FABP5Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (184 aa)
ADH4Alcohol dehydrogenase 4 (class II), pi polypeptide. (447 aa)
ENSFCAP00000054404Uncharacterized protein. (284 aa)
H2AXHistone H2A; Belongs to the histone H2A family. (143 aa)
PRKCZProtein kinase C zeta. (649 aa)
EBAG9Estrogen receptor binding site associated antigen 9. (321 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (276 aa)
YY1YY1 transcription factor. (481 aa)
LOC101089767Histone H4. (103 aa)
ARL4AADP ribosylation factor like GTPase 4A. (187 aa)
AKR1C3Aldo_ket_red domain-containing protein. (419 aa)
USF1Upstream transcription factor 1. (444 aa)
ENSFCAP00000057069Uncharacterized protein. (103 aa)
LOC101098145Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (298 aa)
ZNF217Zinc finger protein 217. (996 aa)
LOC101082235-7Histone H2B type 1. (126 aa)
ZC3H12CZinc finger CCCH-type containing 12C. (890 aa)
ELK1ETS transcription factor ELK1. (487 aa)
ENSFCAP00000058404Uncharacterized protein. (106 aa)
LOC101083921Histone H4. (103 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (152 aa)
ENSFCAP00000059504G protein gamma domain-containing protein. (76 aa)
GNB5G protein subunit beta 5. (403 aa)
UHMK1U2AF homology motif kinase 1. (419 aa)
AKT2Non-specific serine/threonine protein kinase. (571 aa)
KANK3KN motif and ankyrin repeat domains 3. (862 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity). (1213 aa)
ENSFCAP00000060347Uncharacterized protein; Belongs to the calmodulin family. (146 aa)
KANK1KN motif and ankyrin repeat domains 1. (1366 aa)
CRABP2Cellular retinoic acid binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (198 aa)
H2BE1Histone H2B; Belongs to the histone H2B family. (122 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (250 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (498 aa)
ZFP42Uncharacterized protein. (185 aa)
LOC101082235-6Histone H2B type 1. (126 aa)
RARGRetinoic acid receptor gamma. (459 aa)
ENSFCAP00000051025Uncharacterized protein. (165 aa)
LOC101087478Histone H4. (103 aa)
H2BC3Histone H2B; Belongs to the histone H2B family. (126 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CALM1Uncharacterized protein; Belongs to the calmodulin family. (192 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
LOC101086971Histone H2B; Belongs to the histone H2B family. (126 aa)
STRNStriatin. (780 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
PGRProgesterone receptor. (932 aa)
LOC101082235-5Histone H2B type 1. (126 aa)
RXRARetinoid X receptor alpha. (654 aa)
LOC101082235-4Histone H2B type 1. (126 aa)
LOC101084959Histone H3.1. (136 aa)
LOC101080632Histone H3.1. (136 aa)
LOC105260541-3Histone H3.1. (136 aa)
LOC101095347-4Histone H4. (103 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
ENSFCAP00000048881Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC101088485Histone H2B type 1. (125 aa)
LOC101080886Histone H3.1. (136 aa)
LOC101084708Histone H4. (103 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
LOC105260541-2Histone H3.1. (136 aa)
CCNT1CYCLIN domain-containing protein; Belongs to the cyclin family. (184 aa)
LOC101082235-3Histone H2B type 1. (126 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
LOC101083933Histone H4. (103 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (418 aa)
PIK3R3Uncharacterized protein. (461 aa)
LOC101095347-3Histone H4. (103 aa)
FOSProto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] (381 aa)
LOC101088237Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSFCAP00000045932Uncharacterized protein. (123 aa)
PLIN1Perilipin; Belongs to the perilipin family. (522 aa)
LOC101082235-2Histone H2B type 1. (126 aa)
CBFBUncharacterized protein. (187 aa)
LOC101082491Histone H4. (103 aa)
LOC101100603PUM-HD domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (771 aa)
LOC101093269Histone H3.1. (136 aa)
LOC101095347-2Histone H4. (103 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa)
LOC101084193Histone H4. (103 aa)
GATA3GATA binding protein 3. (444 aa)
H3C13H3 clustered histone 13. (136 aa)
ENSFCAP00000043900Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC101085801Uncharacterized protein. (467 aa)
PIK3R2Phosphoinositide-3-kinase regulatory subunit 2. (726 aa)
ENSFCAP00000043372Histone H3; Belongs to the histone H3 family. (136 aa)
PDK3Protein-serine/threonine kinase. (415 aa)
ESR2Estrogen receptor 2. (574 aa)
ENSFCAP00000042498Histone domain-containing protein; Belongs to the histone H2B family. (118 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
LOC101095347Histone H4. (103 aa)
NCOA1Nuclear receptor coactivator. (1492 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (549 aa)
ENSFCAP00000041747Uncharacterized protein; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (88 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (753 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
SRCTyrosine-protein kinase. (678 aa)
LOC105260541Histone H3; Belongs to the histone H3 family. (136 aa)
TBL1XUncharacterized protein. (527 aa)
HIST2H3CHistone cluster 2 H3 family member c. (258 aa)
TGFATransforming growth factor alpha. (192 aa)
LOC101082235Histone H2B; Belongs to the histone H2B family. (126 aa)
GREB1LGREB1 like retinoic acid receptor coactivator. (1969 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (558 aa)
EPGNEpithelial mitogen. (153 aa)
MMP2Matrix metallopeptidase 2. (661 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (166 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSFCAP00000039174TFIIF_beta domain-containing protein. (123 aa)
CHRNB1DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the ligand-gated ion channel (TC 1.A.9) family. (2274 aa)
GTF2A1General transcription factor IIA subunit 1. (376 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
KANK2KN motif and ankyrin repeat domains 2. (857 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
ENSFCAP00000036538Uncharacterized protein. (701 aa)
CEP170Centrosomal protein 170. (1588 aa)
TBPL1TATA-box binding protein like 1. (186 aa)
RARARetinoic acid receptor alpha. (462 aa)
DHRS2Dehydrogenase/reductase 2. (281 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1112 aa)
BTCBetacellulin. (194 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
NCOR1Nuclear receptor corepressor 1. (2515 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (498 aa)
TRPS1Transcriptional repressor GATA binding 1. (1294 aa)
PRMT8Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (394 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (221 aa)
DHRS9Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa)
TBPL2TATA-box binding protein like 2. (361 aa)
ZC3H12BZinc finger CCCH-type containing 12B. (838 aa)
FKBP4Peptidylprolyl isomerase. (464 aa)
ENSFCAP00000030326Uncharacterized protein. (122 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
ENSFCAP00000029012Uncharacterized protein; Belongs to the calmodulin family. (124 aa)
ENSFCAP00000028809Histone H2B; Belongs to the histone H2B family. (67 aa)
LOC101097703EF-hand domain-containing protein; Belongs to the calmodulin family. (86 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (492 aa)
CPT1BCarnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
SRBD1S1 RNA binding domain 1. (1012 aa)
PRMT1Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
ENSFCAP00000028340Uncharacterized protein. (110 aa)
GNAI3G protein subunit alpha i3. (354 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
POLR2JRNA polymerase II subunit J. (117 aa)
LOC109498222Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa)
ENSFCAP00000027305Uncharacterized protein. (79 aa)
PPARDPeroxisome proliferator activated receptor delta. (464 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (299 aa)
GNB4G protein subunit beta 4. (340 aa)
LOC101087401Histone H2A; Belongs to the histone H2A family. (128 aa)
ENSFCAP00000026553Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (58 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
ARL4CADP ribosylation factor like GTPase 4C; Belongs to the small GTPase superfamily. Arf family. (202 aa)
ENSFCAP00000025898Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (65 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the PP2C family. (698 aa)
PDK1Protein-serine/threonine kinase. (449 aa)
M3XDD6_FELCAHistone domain-containing protein; Belongs to the histone H2B family. (121 aa)
CHD1Chromodomain helicase DNA binding protein 1. (1655 aa)
GPS2Uncharacterized protein. (327 aa)
NCOR2Nuclear receptor corepressor 2. (2458 aa)
DHRSXDehydrogenase/reductase X-linked. (330 aa)
LOC101097798Histone H2A; Belongs to the histone H2A family. (113 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
FOXO3Forkhead box O3. (672 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
LOC101092488Histone domain-containing protein; Belongs to the histone H2B family. (127 aa)
GNG14Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNB2G protein subunit beta 2. (340 aa)
LOC101100387PKS_ER domain-containing protein. (375 aa)
ZDHHC7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (308 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
LOC101088423Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
PPIDPeptidylprolyl isomerase D. (370 aa)
FOXA1Forkhead box A1. (536 aa)
KANK4KN motif and ankyrin repeat domains 4. (1013 aa)
CSDE1Cold shock domain containing E1. (844 aa)
ESR1Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] (595 aa)
GTF2A1LGeneral transcription factor IIA subunit 1 like. (477 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
H3F3AHistone H3; Belongs to the histone H3 family. (136 aa)
FKBP5Peptidylprolyl isomerase. (457 aa)
LOC101096314Histone H2B; Belongs to the histone H2B family. (126 aa)
M3WZ36_FELCAHistone H2A; Belongs to the histone H2A family. (140 aa)
UPK3BL2Uncharacterized protein. (253 aa)
CAV2Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...] (262 aa)
NCOA2Nuclear receptor coactivator. (1470 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
EREGEpiregulin. (169 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
GNB1G protein subunit beta 1. (340 aa)
PDK4Protein-serine/threonine kinase. (412 aa)
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (551 aa)
M3WQU5_FELCAEF-hand domain-containing protein; Belongs to the calmodulin family. (77 aa)
TFF3Trefoil factor 3; Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen) (By similarity). (80 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (149 aa)
SP1Sp1 transcription factor. (786 aa)
M3WPU0_FELCAUncharacterized protein. (162 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
KRASUncharacterized protein. (380 aa)
MMP3Matrix metallopeptidase 3. (478 aa)
MMP7Matrilysin; Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase; Belongs to the peptidase M10A family. (267 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (647 aa)
NCOA3Nuclear receptor coactivator. (1412 aa)
SDR16C5Short chain dehydrogenase/reductase family 16C member 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (326 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (127 aa)
RDH16Retinol dehydrogenase 16; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (344 aa)
PPP5CSerine/threonine-protein phosphatase. (573 aa)
RDH5Retinol dehydrogenase 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (331 aa)
KDM1ALysine demethylase 1A. (944 aa)
STRN3Striatin 3. (795 aa)
WDR64WD repeat domain 64. (1089 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (397 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (517 aa)
GNB3G protein subunit beta 3. (339 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
RXRGRetinoid X receptor gamma. (463 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
CXXC5CXXC finger protein 5. (320 aa)
CRABP1Cellular retinoic acid binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (137 aa)
RARBRetinoic acid receptor beta. (448 aa)
GNG13G protein subunit gamma 13. (67 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (522 aa)
PDK2Protein-serine/threonine kinase. (407 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (457 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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