STRINGSTRING
ANKRD33 ANKRD33 DOCK2 DOCK2 MCAM MCAM RNFT2 RNFT2 TIAM1 TIAM1 DOCK3 DOCK3 CLRN2 CLRN2 SWAP70 SWAP70 PAK1 PAK1 PREX1 PREX1 BCAM BCAM CDC42 CDC42 VAV1 VAV1 LAMTOR1 LAMTOR1 RNFT1 RNFT1 DEF6 DEF6 CYBA CYBA VAMP3 VAMP3 ARMCX2 ARMCX2 WASF2 WASF2 MPP7 MPP7 ARHGAP26 ARHGAP26 VAPB VAPB RACGAP1 RACGAP1 EPHA2 EPHA2 VANGL1 VANGL1 PIK3R1 PIK3R1 BRK1 BRK1 EMD EMD VAV2 VAV2 ABR ABR DOCK4 DOCK4 ABI2 ABI2 ARHGAP32 ARHGAP32 CYFIP1 CYFIP1 ARHGAP1 ARHGAP1 ESYT1 ESYT1 ELOVL7 ELOVL7 PNPLA3 PNPLA3 NCF4 NCF4 LEMD3 LEMD3 DIAPH3 DIAPH3 RAB7A RAB7A BCR BCR PAK2 PAK2 PAK4 PAK4 RBM39 RBM39 STBD1 STBD1 ABI1 ABI1 NCF2 NCF2 TAOK3 TAOK3 LOC101100956 LOC101100956 ARMCX3 ARMCX3 CDC42-2 CDC42-2 PGRMC2 PGRMC2 M3XEZ6_FELCA M3XEZ6_FELCA MTX3 MTX3 ARHGAP39 ARHGAP39 NCKAP1 NCKAP1 DOCK10 DOCK10 CAV1 CAV1 ARHGDIA ARHGDIA SLITRK5 SLITRK5 CDC42EP4 CDC42EP4 GIT1 GIT1 ARHGAP42 ARHGAP42 ITGB1 ITGB1 TFRC TFRC CLRN3 CLRN3 IQGAP1 IQGAP1 KIAA0355 KIAA0355 SYDE1 SYDE1 PIK3CA PIK3CA ENSFCAP00000038726 ENSFCAP00000038726 ENSFCAP00000039879 ENSFCAP00000039879 MPP3 MPP3 ARHGAP21 ARHGAP21 NCKAP1L NCKAP1L PIK3R2 PIK3R2 ARHGAP35 ARHGAP35 ERBIN ERBIN VAV3 VAV3 PIK3R3 PIK3R3 ARHGAP17 ARHGAP17 NHS NHS SGSM3 SGSM3 OPHN1 OPHN1 RAC3 RAC3 TRIO-2 TRIO-2 ARMC10 ARMC10 MCF2 MCF2 RAC2 RAC2 ANKRD33B ANKRD33B BAIAP2L1 BAIAP2L1 VRK2 VRK2 CPLX4 CPLX4 ANKLE2 ANKLE2 GIT2 GIT2 NCF1 NCF1 ENSFCAP00000059861 ENSFCAP00000059861 CDC42EP1 CDC42EP1 MTX1 MTX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANKRD33Ankyrin repeat domain 33. (272 aa)
DOCK2Dedicator of cytokinesis 2; Belongs to the DOCK family. (1830 aa)
MCAMMelanoma cell adhesion molecule. (681 aa)
RNFT2Ring finger protein, transmembrane 2. (445 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1591 aa)
DOCK3Dedicator of cytokinesis 3; Belongs to the DOCK family. (2024 aa)
CLRN2Clarin 2. (232 aa)
SWAP70Switching B cell complex subunit SWAP70. (585 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1647 aa)
BCAMBasal cell adhesion molecule (Lutheran blood group). (628 aa)
CDC42Uncharacterized protein. (191 aa)
VAV1Vav guanine nucleotide exchange factor 1. (846 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
RNFT1Ring finger protein, transmembrane 1. (435 aa)
DEF6DEF6 guanine nucleotide exchange factor. (631 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (194 aa)
VAMP3Vesicle associated membrane protein 3. (103 aa)
ARMCX2Armadillo repeat containing X-linked 2. (609 aa)
WASF2WASP family member 2. (498 aa)
MPP7Membrane palmitoylated protein 7; Belongs to the MAGUK family. (576 aa)
ARHGAP26Rho GTPase activating protein 26. (770 aa)
VAPBVAMP associated protein B and C. (243 aa)
RACGAP1Rac GTPase activating protein 1. (668 aa)
EPHA2EPH receptor A2. (936 aa)
VANGL1Vang-like protein. (520 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
EMDEmerin. (260 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
ABRABR activator of RhoGEF and GTPase. (871 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (1970 aa)
ABI2Abl interactor 2. (542 aa)
ARHGAP32Rho GTPase activating protein 32. (2086 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
ARHGAP1Rho GTPase activating protein 1. (449 aa)
ESYT1Extended synaptotagmin 1. (1104 aa)
ELOVL7DEP domain containing 1B. (529 aa)
PNPLA3Uncharacterized protein. (919 aa)
NCF4Neutrophil cytosolic factor 4. (339 aa)
LEMD3LEM domain containing 3. (915 aa)
DIAPH3Diaphanous related formin 3. (1188 aa)
RAB7AUncharacterized protein. (207 aa)
BCRBCR activator of RhoGEF and GTPase. (1282 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
PAK4Non-specific serine/threonine protein kinase. (592 aa)
RBM39RNA binding motif protein 39. (530 aa)
STBD1Starch binding domain 1. (361 aa)
ABI1Abl interactor 1. (508 aa)
NCF2Neutrophil cytosolic factor 2. (526 aa)
TAOK3TAO kinase 3. (914 aa)
LOC101100956Uncharacterized protein. (129 aa)
ARMCX3Armadillo repeat containing X-linked 3. (379 aa)
CDC42-2Uncharacterized protein. (191 aa)
PGRMC2Progesterone receptor membrane component 2; Belongs to the cytochrome b5 family. (255 aa)
M3XEZ6_FELCAUncharacterized protein. (183 aa)
MTX3Metaxin. (312 aa)
ARHGAP39Rho GTPase activating protein 39. (1102 aa)
NCKAP1NCK associated protein 1. (1134 aa)
DOCK10Dedicator of cytokinesis 10; Belongs to the DOCK family. (2220 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
ARHGDIAUncharacterized protein. (425 aa)
SLITRK5SLIT and NTRK like family member 5. (958 aa)
CDC42EP4CDC42 effector protein 4. (279 aa)
GIT1GIT ArfGAP 1. (770 aa)
ARHGAP42Rho GTPase activating protein 42. (874 aa)
ITGB1Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (801 aa)
TFRCTransferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity); Belongs to the [...] (789 aa)
CLRN3Clarin 3. (229 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1657 aa)
KIAA0355KIAA0355. (1069 aa)
SYDE1Synapse defective Rho GTPase homolog 1. (668 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ENSFCAP00000038726Uncharacterized protein. (134 aa)
ENSFCAP00000039879Uncharacterized protein. (148 aa)
MPP3Membrane palmitoylated protein 3; Belongs to the MAGUK family. (613 aa)
ARHGAP21Rho GTPase activating protein 21. (1950 aa)
NCKAP1LNCK associated protein 1 like. (1179 aa)
PIK3R2Phosphoinositide-3-kinase regulatory subunit 2. (726 aa)
ARHGAP35Rho GTPase activating protein 35. (1500 aa)
ERBINErbb2 interacting protein. (1461 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
PIK3R3Uncharacterized protein. (461 aa)
ARHGAP17Rho GTPase activating protein 17. (863 aa)
NHSNHS actin remodeling regulator. (1624 aa)
SGSM3Small G protein signaling modulator 3. (805 aa)
OPHN1Oligophrenin 1. (823 aa)
RAC3Rac family small GTPase 3. (205 aa)
TRIO-2Uncharacterized protein. (1847 aa)
ARMC10Armadillo repeat containing 10. (412 aa)
MCF2MCF.2 cell line derived transforming sequence. (1030 aa)
RAC2Rac family small GTPase 2. (234 aa)
ANKRD33BAnkyrin repeat domain 33B. (604 aa)
BAIAP2L1BAI1 associated protein 2 like 1. (530 aa)
VRK2VRK serine/threonine kinase 2. (495 aa)
CPLX4Lectin, mannose binding 1. (611 aa)
ANKLE2Ankyrin repeat and LEM domain containing 2. (1012 aa)
GIT2GIT ArfGAP 2. (786 aa)
NCF1Neutrophil cytosolic factor 1. (390 aa)
ENSFCAP00000059861GST_C_6 domain-containing protein. (313 aa)
CDC42EP1CDC42 effector protein 1. (525 aa)
MTX1Metaxin 1. (517 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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