10 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CRB1	Crumbs cell polarity complex component 1. (1405 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	YWHAZ	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa)
	HES5	Hes family bHLH transcription factor 5. (166 aa)
	HES4	Hes family bHLH transcription factor 4. (210 aa)
	HES1	Hes family bHLH transcription factor 1. (280 aa)
	ENSFCAP00000056245	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (178 aa)
	ENSFCAP00000057780	Uncharacterized protein. (585 aa)
	ENSFCAP00000057918	Uncharacterized protein. (293 aa)
	AKT2	Non-specific serine/threonine protein kinase. (571 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSFCAP00000004586	ENSFCAP00000059662	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.901
AKT1	ENSFCAP00000057780	ENSFCAP00000004586	ENSFCAP00000057780	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.494
AKT1	ENSFCAP00000057918	ENSFCAP00000004586	ENSFCAP00000057918	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.494
AKT1	YWHAZ	ENSFCAP00000004586	ENSFCAP00000018314	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family.	0.415
AKT2	AKT1	ENSFCAP00000059662	ENSFCAP00000004586	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901
AKT2	ENSFCAP00000057780	ENSFCAP00000059662	ENSFCAP00000057780	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.494
AKT2	ENSFCAP00000057918	ENSFCAP00000059662	ENSFCAP00000057918	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.494
ENSFCAP00000056245	ENSFCAP00000057780	ENSFCAP00000056245	ENSFCAP00000057780	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Uncharacterized protein.	0.615
ENSFCAP00000056245	ENSFCAP00000057918	ENSFCAP00000056245	ENSFCAP00000057918	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Uncharacterized protein.	0.615
ENSFCAP00000057780	AKT1	ENSFCAP00000057780	ENSFCAP00000004586	Uncharacterized protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.494
ENSFCAP00000057780	AKT2	ENSFCAP00000057780	ENSFCAP00000059662	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.494
ENSFCAP00000057780	ENSFCAP00000056245	ENSFCAP00000057780	ENSFCAP00000056245	Uncharacterized protein.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.615
ENSFCAP00000057780	HES1	ENSFCAP00000057780	ENSFCAP00000051323	Uncharacterized protein.	Hes family bHLH transcription factor 1.	0.500
ENSFCAP00000057780	HES5	ENSFCAP00000057780	ENSFCAP00000041405	Uncharacterized protein.	Hes family bHLH transcription factor 5.	0.596
ENSFCAP00000057780	YWHAZ	ENSFCAP00000057780	ENSFCAP00000018314	Uncharacterized protein.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family.	0.615
ENSFCAP00000057918	AKT1	ENSFCAP00000057918	ENSFCAP00000004586	Uncharacterized protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.494
ENSFCAP00000057918	AKT2	ENSFCAP00000057918	ENSFCAP00000059662	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.494
ENSFCAP00000057918	ENSFCAP00000056245	ENSFCAP00000057918	ENSFCAP00000056245	Uncharacterized protein.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.615
ENSFCAP00000057918	HES1	ENSFCAP00000057918	ENSFCAP00000051323	Uncharacterized protein.	Hes family bHLH transcription factor 1.	0.500
ENSFCAP00000057918	YWHAZ	ENSFCAP00000057918	ENSFCAP00000018314	Uncharacterized protein.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family.	0.615