45 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MCAM	Melanoma cell adhesion molecule. (681 aa)
	MYO9B	Myosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2162 aa)
	RHOF	Ras homolog family member F, filopodia associated. (206 aa)
	BAIAP2L2	BAI1 associated protein 2 like 2. (562 aa)
	LMNB1	Lamin B1; Belongs to the intermediate filament family. (586 aa)
	BCAM	Basal cell adhesion molecule (Lutheran blood group). (628 aa)
	VAMP3	Vesicle associated membrane protein 3. (103 aa)
	VANGL1	Vang-like protein. (520 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
	ARHGAP32	Rho GTPase activating protein 32. (2086 aa)
	ARHGAP1	Rho GTPase activating protein 1. (449 aa)
	ESYT1	Extended synaptotagmin 1. (1104 aa)
	ELOVL7	DEP domain containing 1B. (529 aa)
	DIAPH3	Diaphanous related formin 3. (1188 aa)
	RAB7A	Uncharacterized protein. (207 aa)
	ARHGAP5	Rho GTPase activating protein 5. (1503 aa)
	ARHGAP12	Rho GTPase activating protein 12. (846 aa)
	SLC4A7	Anion exchange protein. (1258 aa)
	ARHGAP39	Rho GTPase activating protein 39. (1102 aa)
	STEAP3	STEAP3 metalloreductase. (522 aa)
	CAV1	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
	FARP1	FERM, ARH/RhoGEF and pleckstrin domain protein 1. (1043 aa)
	FAM169B	Uncharacterized protein. (372 aa)
	SYDE1	Synapse defective Rho GTPase homolog 1. (668 aa)
	SRGAP2	Uncharacterized protein. (1084 aa)
	ENSFCAP00000038726	Uncharacterized protein. (134 aa)
	FAM169A	Family with sequence similarity 169 member A. (670 aa)
	CAPZB	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (301 aa)
	ARHGAP21	Rho GTPase activating protein 21. (1950 aa)
	LOC101096439	Uncharacterized protein. (473 aa)
	PIK3R2	Phosphoinositide-3-kinase regulatory subunit 2. (726 aa)
	SENP1	SUMO specific peptidase 1. (745 aa)
	ADD3	Adducin 3. (706 aa)
	BASP1	Uncharacterized protein. (106 aa)
	SOWAHC	Sosondowah ankyrin repeat domain family member C. (549 aa)
	LMNB2	Lamin B2; Belongs to the intermediate filament family. (718 aa)
	ACTN1	Actinin alpha 1. (927 aa)
	TOR1AIP1	Torsin 1A interacting protein 1. (614 aa)
	AKAP12	A-kinase anchoring protein 12. (1505 aa)
	BAIAP2L1	BAI1 associated protein 2 like 1. (530 aa)
	DIAPH2	Diaphanous related formin 2. (1101 aa)
	SOWAHA	Sosondowah ankyrin repeat domain family member A. (569 aa)
	MTMR1	Myotubularin related protein 1. (732 aa)
	SNAP23	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (257 aa)
	DIAPH1	Diaphanous related formin 1. (1290 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN1	ARHGAP1	ENSFCAP00000052988	ENSFCAP00000012646	Actinin alpha 1.	Rho GTPase activating protein 1.	0.451
ACTN1	CAPZB	ENSFCAP00000052988	ENSFCAP00000042169	Actinin alpha 1.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.539
ACTN1	CAV1	ENSFCAP00000052988	ENSFCAP00000029296	Actinin alpha 1.	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...]	0.461
ACTN1	RHOF	ENSFCAP00000052988	ENSFCAP00000001241	Actinin alpha 1.	Ras homolog family member F, filopodia associated.	0.581
ADD3	ARHGAP1	ENSFCAP00000046485	ENSFCAP00000012646	Adducin 3.	Rho GTPase activating protein 1.	0.421
ADD3	CAPZB	ENSFCAP00000046485	ENSFCAP00000042169	Adducin 3.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.401
ADD3	CAV1	ENSFCAP00000046485	ENSFCAP00000029296	Adducin 3.	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...]	0.430
ADD3	RHOF	ENSFCAP00000046485	ENSFCAP00000001241	Adducin 3.	Ras homolog family member F, filopodia associated.	0.521
AKAP12	BASP1	ENSFCAP00000054454	ENSFCAP00000049337	A-kinase anchoring protein 12.	Uncharacterized protein.	0.453
AKAP12	CAPZB	ENSFCAP00000054454	ENSFCAP00000042169	A-kinase anchoring protein 12.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.444
AKAP12	RHOF	ENSFCAP00000054454	ENSFCAP00000001241	A-kinase anchoring protein 12.	Ras homolog family member F, filopodia associated.	0.554
ARHGAP1	ACTN1	ENSFCAP00000012646	ENSFCAP00000052988	Rho GTPase activating protein 1.	Actinin alpha 1.	0.451
ARHGAP1	ADD3	ENSFCAP00000012646	ENSFCAP00000046485	Rho GTPase activating protein 1.	Adducin 3.	0.421
ARHGAP1	ARHGAP39	ENSFCAP00000012646	ENSFCAP00000027809	Rho GTPase activating protein 1.	Rho GTPase activating protein 39.	0.529
ARHGAP1	BAIAP2L1	ENSFCAP00000012646	ENSFCAP00000056965	Rho GTPase activating protein 1.	BAI1 associated protein 2 like 1.	0.424
ARHGAP1	CAPZB	ENSFCAP00000012646	ENSFCAP00000042169	Rho GTPase activating protein 1.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.584
ARHGAP1	DIAPH1	ENSFCAP00000012646	ENSFCAP00000061817	Rho GTPase activating protein 1.	Diaphanous related formin 1.	0.443
ARHGAP1	DIAPH2	ENSFCAP00000012646	ENSFCAP00000057393	Rho GTPase activating protein 1.	Diaphanous related formin 2.	0.431
ARHGAP1	DIAPH3	ENSFCAP00000012646	ENSFCAP00000016593	Rho GTPase activating protein 1.	Diaphanous related formin 3.	0.465
ARHGAP1	MYO9B	ENSFCAP00000012646	ENSFCAP00000000929	Rho GTPase activating protein 1.	Myosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.733