STRINGSTRING
MTMR14 MTMR14 RRAGB RRAGB CRYBB3 CRYBB3 ATG13 ATG13 AMBRA1 AMBRA1 LOC101094500 LOC101094500 CRYGN CRYGN ATG16L2 ATG16L2 ATG9B ATG9B BECN1 BECN1 RHEB RHEB TUBA1C TUBA1C ATG16L1 ATG16L1 ATG9A ATG9A ULK1 ULK1 LOC101099268 LOC101099268 RB1CC1 RB1CC1 UBA52 UBA52 RRAGC RRAGC CETN1 CETN1 GABARAPL2 GABARAPL2 USP30 USP30 DYNC1LI1 DYNC1LI1 M3W868_FELCA M3W868_FELCA CSNK2B CSNK2B ATG12 ATG12 TUBB1 TUBB1 GFAP GFAP LAMTOR1 LAMTOR1 ULK2 ULK2 UBE2N UBE2N LOC101090556 LOC101090556 TUBB4B TUBB4B CHMP2A CHMP2A TOMM22 TOMM22 WDR45B WDR45B PRKAB1 PRKAB1 IFT88 IFT88 PINK1 PINK1 TUBAL3 TUBAL3 PEX5 PEX5 RHEBL1 RHEBL1 MTOR MTOR WIPI1 WIPI1 PLIN2 PLIN2 ATG4D ATG4D WIPI2 WIPI2 UVRAG UVRAG TMEM189 TMEM189 ENSFCAP00000056164 ENSFCAP00000056164 CHMP7 CHMP7 ENSFCAP00000055099 ENSFCAP00000055099 MAP1LC3B MAP1LC3B LAMTOR2 LAMTOR2 DYNC1I1 DYNC1I1 PGAM5 PGAM5 DYNC1H1 DYNC1H1 KIAA1671 KIAA1671 CHMP6 CHMP6 ENSFCAP00000052091 ENSFCAP00000052091 PEX5L PEX5L ILRUN ILRUN VIM VIM TOMM20L TOMM20L TUBA4B TUBA4B SAMD15 SAMD15 GABARAPL1 GABARAPL1 TM9SF1 TM9SF1 CSNK2A1 CSNK2A1 TOMM40 TOMM40 CHMP2B CHMP2B ATG5 ATG5 ATG3 ATG3 DYNC1I2 DYNC1I2 HDAC6 HDAC6 ENSFCAP00000044926 ENSFCAP00000044926 TSC1 TSC1 ATG4A ATG4A LOC101083598 LOC101083598 RNASE1 RNASE1 TUBB4A TUBB4A ENSFCAP00000060319 ENSFCAP00000060319 ATG4B ATG4B ENSFCAP00000059015 ENSFCAP00000059015 ENSFCAP00000058976 ENSFCAP00000058976 PRKN PRKN ENSFCAP00000043103 ENSFCAP00000043103 RPTOR RPTOR ENSFCAP00000041779 ENSFCAP00000041779 PIK3R4 PIK3R4 MAP1LC3C MAP1LC3C CFTR CFTR SRC SRC LAMTOR4 LAMTOR4 TOMM7 TOMM7 ENSFCAP00000039879 ENSFCAP00000039879 DYNLL2 DYNLL2 ATG7 ATG7 KXD1 KXD1 TUBA4A TUBA4A DYNLL1 DYNLL1 VDAC1 VDAC1 ATG101 ATG101 PRKAB2 PRKAB2 PRAF2 PRAF2 TXNDC11 TXNDC11 LOC101095070 LOC101095070 ENSFCAP00000034335 ENSFCAP00000034335 PRKAA2 PRKAA2 CHMP4A CHMP4A ENSFCAP00000034079 ENSFCAP00000034079 TOMM5 TOMM5 TSC2 TSC2 TOMM40L TOMM40L LOC109502223 LOC109502223 PRKAG1 PRKAG1 MFN1 MFN1 PRKAG2 PRKAG2 ENSFCAP00000031232 ENSFCAP00000031232 NBR1 NBR1 ATG10 ATG10 TUBB6 TUBB6 FNDC3B FNDC3B PRKAG3 PRKAG3 TOMM6 TOMM6 MFN2 MFN2 MTMR3 MTMR3 ATG4C ATG4C MLST8 MLST8 LAMTOR3 LAMTOR3 ENSFCAP00000026617 ENSFCAP00000026617 TUBA1A TUBA1A FUNDC1 FUNDC1 ATM ATM PIK3C3 PIK3C3 SLC38A9 SLC38A9 ARL13B ARL13B CHMP4C CHMP4C PRKAA1 PRKAA1 M3XC26_FELCA M3XC26_FELCA MAP1LC3A MAP1LC3A M3X8L9_FELCA M3X8L9_FELCA CETN3 CETN3 LY6G5B LY6G5B CE1H17orf75 CE1H17orf75 GABARAP GABARAP LAMTOR5 LAMTOR5 TOMM20 TOMM20 RRAGA RRAGA RRAGD RRAGD FUNDC2 FUNDC2 TOMM70 TOMM70 FNDC3A FNDC3A CSNK2A2 CSNK2A2 PARK7 PARK7 MDP1 MDP1 TUBE1 TUBE1 CHMP4B CHMP4B RPS27A RPS27A DYNC1LI2 DYNC1LI2 ATG14 ATG14 MTERF3 MTERF3 SQSTM1 SQSTM1 TUBB2A TUBB2A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MTMR14Myotubularin related protein 14. (648 aa)
RRAGBRas related GTP binding B. (374 aa)
CRYBB3Crystallin beta B3; Belongs to the beta/gamma-crystallin family. (211 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1301 aa)
LOC101094500Uncharacterized protein. (274 aa)
CRYGNCrystallin gamma N; Belongs to the beta/gamma-crystallin family. (183 aa)
ATG16L2Autophagy related 16 like 2. (617 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (920 aa)
BECN1Beclin 1. (448 aa)
RHEBRas homolog, mTORC1 binding. (187 aa)
TUBA1CTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (518 aa)
ATG16L1Autophagy related 16 like 1. (623 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (998 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1113 aa)
LOC101099268Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (515 aa)
RB1CC1RB1 inducible coiled-coil 1. (1593 aa)
UBA52Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (128 aa)
RRAGCRas related GTP binding C. (398 aa)
CETN1Centrin 1. (172 aa)
GABARAPL2GABA type A receptor associated protein like 2. (117 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (519 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (524 aa)
M3W868_FELCATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (457 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (472 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1039 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
LOC101090556Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
TOMM22Translocase of outer mitochondrial membrane 22. (142 aa)
WDR45BWD repeat domain 45B. (344 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
IFT88Intraflagellar transport 88. (831 aa)
PINK1PTEN induced kinase 1. (581 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
PEX5Peroxisomal biogenesis factor 5. (640 aa)
RHEBL1RHEB like 1. (183 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2590 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (470 aa)
PLIN2Perilipin; Belongs to the perilipin family. (447 aa)
ATG4DCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (475 aa)
WIPI2WD repeat domain, phosphoinositide interacting 2. (468 aa)
UVRAGUV radiation resistance associated. (718 aa)
TMEM189Transmembrane protein 189. (296 aa)
ENSFCAP00000056164Uncharacterized protein. (88 aa)
CHMP7Charged multivesicular body protein 7. (456 aa)
ENSFCAP00000055099Uncharacterized protein. (115 aa)
MAP1LC3BUncharacterized protein. (309 aa)
LAMTOR2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (149 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (645 aa)
PGAM5Uncharacterized protein. (303 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4670 aa)
KIAA1671KIAA1671. (1838 aa)
CHMP6Charged multivesicular body protein 6. (263 aa)
ENSFCAP00000052091Uncharacterized protein. (1125 aa)
PEX5LPeroxisomal biogenesis factor 5 like. (626 aa)
ILRUNInflammation and lipid regulator with UBA-like and NBR1-like domains. (291 aa)
VIMVimentin; Belongs to the intermediate filament family. (466 aa)
TOMM20LTranslocase of outer mitochondrial membrane 20 like. (152 aa)
TUBA4BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (225 aa)
SAMD15SAM domain-containing protein. (709 aa)
GABARAPL1GABA type A receptor associated protein like 1. (151 aa)
TM9SF1Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (690 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
TOMM40Translocase of outer mitochondrial membrane 40. (361 aa)
CHMP2BCharged multivesicular body protein 2B. (227 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
ATG3Autophagy-related protein 3. (333 aa)
DYNC1I2Dynein cytoplasmic 1 intermediate chain 2. (714 aa)
HDAC6Histone deacetylase 6. (1178 aa)
ENSFCAP00000044926Uncharacterized protein. (107 aa)
TSC1TSC complex subunit 1. (1110 aa)
ATG4ACysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (400 aa)
LOC101083598CheR domain-containing protein. (386 aa)
RNASE1Ribonuclease A family member 1, pancreatic; Belongs to the pancreatic ribonuclease family. (152 aa)
TUBB4ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (456 aa)
ENSFCAP00000060319Uncharacterized protein. (108 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (578 aa)
ENSFCAP00000059015Uncharacterized protein. (263 aa)
ENSFCAP00000058976Uncharacterized protein. (105 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (462 aa)
ENSFCAP00000043103Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (404 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1335 aa)
ENSFCAP00000041779Uncharacterized protein. (112 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)
MAP1LC3CUncharacterized protein. (141 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1481 aa)
SRCTyrosine-protein kinase. (678 aa)
LAMTOR4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (146 aa)
TOMM7Translocase of outer mitochondrial membrane 7. (55 aa)
ENSFCAP00000039879Uncharacterized protein. (148 aa)
DYNLL2Dynein light chain. (89 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (752 aa)
KXD1KxDL motif containing 1. (201 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
DYNLL1Dynein light chain. (89 aa)
VDAC1Voltage dependent anion channel 1. (283 aa)
ATG101Autophagy related 101. (344 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
PRAF2WD repeat domain 45. (361 aa)
TXNDC11Thioredoxin domain containing 11. (961 aa)
LOC101095070Uncharacterized protein. (141 aa)
ENSFCAP00000034335UBIQUITIN_CONJUGAT_2 domain-containing protein. (104 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
CHMP4ACharged multivesicular body protein 4A. (220 aa)
ENSFCAP00000034079UBIQUITIN_CONJUGAT_2 domain-containing protein. (108 aa)
TOMM5Uncharacterized protein. (51 aa)
TSC2TSC complex subunit 2. (1806 aa)
TOMM40LTranslocase of outer mitochondrial membrane 40 like. (324 aa)
LOC109502223Ubiquitin-like domain-containing protein. (176 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (330 aa)
MFN1Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (804 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (569 aa)
ENSFCAP00000031232Uncharacterized protein. (108 aa)
NBR1NBR1 autophagy cargo receptor. (968 aa)
ATG10Autophagy related 10. (353 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
FNDC3BFibronectin type III domain containing 3B. (1207 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (607 aa)
TOMM6Translocase of outer mitochondrial membrane 6. (74 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
MTMR3Myotubularin related protein 3. (1222 aa)
ATG4CCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (458 aa)
MLST8MTOR associated protein, LST8 homolog. (326 aa)
LAMTOR3Uncharacterized protein. (124 aa)
ENSFCAP00000026617Ubiquitin-like domain-containing protein. (78 aa)
TUBA1ATubulin alpha 1a; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (558 aa)
FUNDC1Uncharacterized protein. (155 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
SLC38A9Solute carrier family 38 member 9. (561 aa)
ARL13BADP ribosylation factor like GTPase 13B. (427 aa)
CHMP4CCharged multivesicular body protein 4C. (237 aa)
PRKAA1Non-specific serine/threonine protein kinase. (573 aa)
M3XC26_FELCAUncharacterized protein. (124 aa)
MAP1LC3AMicrotubule associated protein 1 light chain 3 alpha. (121 aa)
M3X8L9_FELCAUncharacterized protein. (306 aa)
CETN3Centrin 3. (167 aa)
LY6G5BLymphocyte antigen 6 family member G5B. (216 aa)
CE1H17orf75Chromosome E1 C17orf75 homolog. (396 aa)
GABARAPGABA type A receptor-associated protein. (117 aa)
LAMTOR5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (91 aa)
TOMM20Translocase of outer mitochondrial membrane 20. (145 aa)
RRAGARas related GTP binding A. (313 aa)
RRAGDRas related GTP binding D. (396 aa)
FUNDC2FUN14 domain containing 2. (190 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (609 aa)
FNDC3AFibronectin type III domain containing 3A. (1199 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
MDP1Uncharacterized protein. (164 aa)
TUBE1Tubulin epsilon 1; Belongs to the tubulin family. (475 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
RPS27ARibosomal protein S27a. (156 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (492 aa)
ATG14Autophagy related 14. (510 aa)
MTERF3Mitochondrial transcription termination factor 3. (417 aa)
SQSTM1Sequestosome 1. (443 aa)
TUBB2ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (475 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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