34 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FOXO6	Forkhead box O6. (557 aa)
	BTG1	BTG anti-proliferation factor 1. (171 aa)
	FOXO1	Forkhead box O1. (662 aa)
	NFYB	Nuclear transcription factor Y subunit beta. (207 aa)
	SMAD3	Mothers against decapentaplegic homolog. (457 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	FOXO4	Forkhead box O4. (515 aa)
	YWHAG	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (289 aa)
	SIRT1	Sirtuin 1. (745 aa)
	ENSFCAP00000026949	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (135 aa)
	FOXO3	Forkhead box O3. (672 aa)
	CCNG2	Cyclin G2; Belongs to the cyclin family. (343 aa)
	YWHAZ	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa)
	NFYA	Nuclear transcription factor Y subunit alpha. (347 aa)
	GDF11	Growth differentiation factor 11. (404 aa)
	MSTN	Myostatin. (375 aa)
	YWHAB	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
	BCL6	BCL6 transcription repressor. (745 aa)
	CREBBP	CREB binding protein. (2444 aa)
	EP300	E1A binding protein p300. (2425 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	KAT2B	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (834 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	DDIT3	DNA damage inducible transcript 3. (167 aa)
	SFN	Stratifin; Belongs to the 14-3-3 family. (252 aa)
	AKT2	Non-specific serine/threonine protein kinase. (571 aa)
	YWHAQ	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (301 aa)
	SMAD2	Mothers against decapentaplegic homolog. (721 aa)
	SIRT3	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (417 aa)
	BCL6B	BCL6B transcription repressor. (594 aa)
	ENSFCAP00000056245	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (178 aa)
	PPARGC1A	PPARG coactivator 1 alpha. (803 aa)
	NFYC	Nuclear transcription factor Y subunit gamma. (439 aa)
	FOXG1	Forkhead box G1. (483 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSFCAP00000004586	ENSFCAP00000059662	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.901
AKT1	AKT3	ENSFCAP00000004586	ENSFCAP00000003410	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.917
AKT1	FOXO1	ENSFCAP00000004586	ENSFCAP00000039549	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box O1.	0.974
AKT1	FOXO3	ENSFCAP00000004586	ENSFCAP00000022859	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box O3.	0.974
AKT1	FOXO4	ENSFCAP00000004586	ENSFCAP00000031271	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box O4.	0.967
AKT1	FOXO6	ENSFCAP00000004586	ENSFCAP00000049848	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box O6.	0.967
AKT1	SMAD4	ENSFCAP00000004586	ENSFCAP00000031311	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mothers against decapentaplegic homolog.	0.432
AKT1	YWHAZ	ENSFCAP00000004586	ENSFCAP00000018314	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family.	0.415
AKT2	AKT1	ENSFCAP00000059662	ENSFCAP00000004586	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901
AKT2	AKT3	ENSFCAP00000059662	ENSFCAP00000003410	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.918
AKT2	FOXO1	ENSFCAP00000059662	ENSFCAP00000039549	Non-specific serine/threonine protein kinase.	Forkhead box O1.	0.972
AKT2	FOXO3	ENSFCAP00000059662	ENSFCAP00000022859	Non-specific serine/threonine protein kinase.	Forkhead box O3.	0.967
AKT2	FOXO4	ENSFCAP00000059662	ENSFCAP00000031271	Non-specific serine/threonine protein kinase.	Forkhead box O4.	0.967
AKT2	FOXO6	ENSFCAP00000059662	ENSFCAP00000049848	Non-specific serine/threonine protein kinase.	Forkhead box O6.	0.967
AKT2	SIRT1	ENSFCAP00000059662	ENSFCAP00000027641	Non-specific serine/threonine protein kinase.	Sirtuin 1.	0.442
AKT2	SMAD4	ENSFCAP00000059662	ENSFCAP00000031311	Non-specific serine/threonine protein kinase.	Mothers against decapentaplegic homolog.	0.432
AKT3	AKT1	ENSFCAP00000003410	ENSFCAP00000004586	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.917
AKT3	AKT2	ENSFCAP00000003410	ENSFCAP00000059662	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.918
AKT3	FOXO1	ENSFCAP00000003410	ENSFCAP00000039549	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box O1.	0.968
AKT3	FOXO3	ENSFCAP00000003410	ENSFCAP00000022859	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box O3.	0.967