12 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	UBE2N	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	PELI2	E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (464 aa)
	UBA52	Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (128 aa)
	IRAK1	Interleukin 1 receptor associated kinase 1. (724 aa)
	RPS27A	Ribosomal protein S27a. (156 aa)
	IKBKG	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (423 aa)
	PELI1	E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
	LOC109502223	Ubiquitin-like domain-containing protein. (176 aa)
	IKBKB	Inhibitor of nuclear factor kappa B kinase subunit beta. (760 aa)
	PELI3	E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (469 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
	CHUK	Component of inhibitor of nuclear factor kappa B kinase complex. (774 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHUK	IKBKB	ENSFCAP00000060797	ENSFCAP00000044529	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.999
CHUK	IKBKG	ENSFCAP00000060797	ENSFCAP00000020981	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.999
CHUK	IRAK1	ENSFCAP00000060797	ENSFCAP00000010077	Component of inhibitor of nuclear factor kappa B kinase complex.	Interleukin 1 receptor associated kinase 1.	0.975
CHUK	LOC109502223	ENSFCAP00000060797	ENSFCAP00000032729	Component of inhibitor of nuclear factor kappa B kinase complex.	Ubiquitin-like domain-containing protein.	0.581
CHUK	PELI1	ENSFCAP00000060797	ENSFCAP00000027039	Component of inhibitor of nuclear factor kappa B kinase complex.	E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.	0.496
CHUK	PELI2	ENSFCAP00000060797	ENSFCAP00000008050	Component of inhibitor of nuclear factor kappa B kinase complex.	E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.	0.485
CHUK	PELI3	ENSFCAP00000060797	ENSFCAP00000045645	Component of inhibitor of nuclear factor kappa B kinase complex.	E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.	0.485
CHUK	RPS27A	ENSFCAP00000060797	ENSFCAP00000018695	Component of inhibitor of nuclear factor kappa B kinase complex.	Ribosomal protein S27a.	0.581
CHUK	TRAF6	ENSFCAP00000060797	ENSFCAP00000047805	Component of inhibitor of nuclear factor kappa B kinase complex.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.991
CHUK	UBA52	ENSFCAP00000060797	ENSFCAP00000009037	Component of inhibitor of nuclear factor kappa B kinase complex.	Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...]	0.648
CHUK	UBE2N	ENSFCAP00000060797	ENSFCAP00000003927	Component of inhibitor of nuclear factor kappa B kinase complex.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.476
IKBKB	CHUK	ENSFCAP00000044529	ENSFCAP00000060797	Inhibitor of nuclear factor kappa B kinase subunit beta.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.999
IKBKB	IKBKG	ENSFCAP00000044529	ENSFCAP00000020981	Inhibitor of nuclear factor kappa B kinase subunit beta.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.999
IKBKB	IRAK1	ENSFCAP00000044529	ENSFCAP00000010077	Inhibitor of nuclear factor kappa B kinase subunit beta.	Interleukin 1 receptor associated kinase 1.	0.554
IKBKB	LOC109502223	ENSFCAP00000044529	ENSFCAP00000032729	Inhibitor of nuclear factor kappa B kinase subunit beta.	Ubiquitin-like domain-containing protein.	0.489
IKBKB	PELI1	ENSFCAP00000044529	ENSFCAP00000027039	Inhibitor of nuclear factor kappa B kinase subunit beta.	E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.	0.421
IKBKB	PELI2	ENSFCAP00000044529	ENSFCAP00000008050	Inhibitor of nuclear factor kappa B kinase subunit beta.	E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.	0.421
IKBKB	PELI3	ENSFCAP00000044529	ENSFCAP00000045645	Inhibitor of nuclear factor kappa B kinase subunit beta.	E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.	0.421
IKBKB	RPS27A	ENSFCAP00000044529	ENSFCAP00000018695	Inhibitor of nuclear factor kappa B kinase subunit beta.	Ribosomal protein S27a.	0.489
IKBKB	TRAF6	ENSFCAP00000044529	ENSFCAP00000047805	Inhibitor of nuclear factor kappa B kinase subunit beta.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.989