Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKT2 | COL5A3 | ENSFCAP00000059662 | ENSFCAP00000053162 | Non-specific serine/threonine protein kinase. | Collagen type V alpha 3 chain. | 0.600 |
| AKT2 | IRS1 | ENSFCAP00000059662 | ENSFCAP00000018155 | Non-specific serine/threonine protein kinase. | Insulin receptor substrate 1. | 0.493 |
| CALML4 | CALML6 | ENSFCAP00000006036 | ENSFCAP00000005760 | Calmodulin like 4. | Calmodulin like 6. | 0.455 |
| CALML4 | ENSFCAP00000043586 | ENSFCAP00000006036 | ENSFCAP00000043586 | Calmodulin like 4. | Uncharacterized protein. | 0.548 |
| CALML4 | LOC101097703 | ENSFCAP00000006036 | ENSFCAP00000028786 | Calmodulin like 4. | EF-hand domain-containing protein; Belongs to the calmodulin family. | 0.471 |
| CALML4 | TNF | ENSFCAP00000006036 | ENSFCAP00000051032 | Calmodulin like 4. | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.424 |
| CALML6 | CALML4 | ENSFCAP00000005760 | ENSFCAP00000006036 | Calmodulin like 6. | Calmodulin like 4. | 0.455 |
| CALML6 | ENSFCAP00000043586 | ENSFCAP00000005760 | ENSFCAP00000043586 | Calmodulin like 6. | Uncharacterized protein. | 0.476 |
| COL5A3 | AKT2 | ENSFCAP00000053162 | ENSFCAP00000059662 | Collagen type V alpha 3 chain. | Non-specific serine/threonine protein kinase. | 0.600 |
| ENSFCAP00000043586 | CALML4 | ENSFCAP00000043586 | ENSFCAP00000006036 | Uncharacterized protein. | Calmodulin like 4. | 0.548 |
| ENSFCAP00000043586 | CALML6 | ENSFCAP00000043586 | ENSFCAP00000005760 | Uncharacterized protein. | Calmodulin like 6. | 0.476 |
| ENSFCAP00000043586 | TNF | ENSFCAP00000043586 | ENSFCAP00000051032 | Uncharacterized protein. | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.437 |
| IL6 | PPARG | ENSFCAP00000022423 | ENSFCAP00000050722 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.715 |
| IL6 | SOCS3 | ENSFCAP00000022423 | ENSFCAP00000019517 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] | Suppressor of cytokine signaling 3. | 0.850 |
| IL6 | TLR4 | ENSFCAP00000022423 | ENSFCAP00000023731 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] | 0.999 |
| IL6 | TNF | ENSFCAP00000022423 | ENSFCAP00000051032 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.945 |
| INSR | IRS1 | ENSFCAP00000030603 | ENSFCAP00000018155 | Tyrosine-protein kinase receptor. | Insulin receptor substrate 1. | 0.981 |
| INSR | PPARG | ENSFCAP00000030603 | ENSFCAP00000050722 | Tyrosine-protein kinase receptor. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.503 |
| INSR | SOCS3 | ENSFCAP00000030603 | ENSFCAP00000019517 | Tyrosine-protein kinase receptor. | Suppressor of cytokine signaling 3. | 0.949 |
| IRS1 | AKT2 | ENSFCAP00000018155 | ENSFCAP00000059662 | Insulin receptor substrate 1. | Non-specific serine/threonine protein kinase. | 0.493 |
page 1 of 3