19 items (Felis catus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	NR3C1	Uncharacterized protein. (843 aa)
	FABP3	Fatty acid binding protein 3; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa)
	INSR	Tyrosine-protein kinase receptor. (1381 aa)
	CASP3	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (302 aa)
	BECN1	Beclin 1. (448 aa)
	IGF2	Insulin like growth factor 2. (280 aa)
	ANGPT1	Angiopoietin 1. (498 aa)
	SLC1A6	Amino acid transporter. (564 aa)
	IGFBP1	Insulin like growth factor binding protein 1. (247 aa)
	SLC1A5	Amino acid transporter. (541 aa)
	SLC1A3	Amino acid transporter. (542 aa)
	IGF2R	Insulin like growth factor 2 receptor. (2497 aa)
	ANGPT2	Angiopoietin 2. (494 aa)
	BCL2	BCL2 apoptosis regulator. (237 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity). (1213 aa)
	SLC1A7	Amino acid transporter. (624 aa)
	SLC1A1	Amino acid transporter. (486 aa)
	SLC1A2	Amino acid transporter. (579 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1367 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANGPT1	ANGPT2	ENSFCAP00000046812	ENSFCAP00000013334	Angiopoietin 1.	Angiopoietin 2.	0.921
ANGPT1	IGF1R	ENSFCAP00000046812	ENSFCAP00000016299	Angiopoietin 1.	Tyrosine-protein kinase receptor.	0.687
ANGPT1	INSR	ENSFCAP00000046812	ENSFCAP00000030603	Angiopoietin 1.	Tyrosine-protein kinase receptor.	0.673
ANGPT2	ANGPT1	ENSFCAP00000013334	ENSFCAP00000046812	Angiopoietin 2.	Angiopoietin 1.	0.921
ANGPT2	IGF1R	ENSFCAP00000013334	ENSFCAP00000016299	Angiopoietin 2.	Tyrosine-protein kinase receptor.	0.720
ANGPT2	INSR	ENSFCAP00000013334	ENSFCAP00000030603	Angiopoietin 2.	Tyrosine-protein kinase receptor.	0.669
BCL2	BECN1	ENSFCAP00000062072	ENSFCAP00000012183	BCL2 apoptosis regulator.	Beclin 1.	0.999
BCL2	CASP3	ENSFCAP00000062072	ENSFCAP00000031946	BCL2 apoptosis regulator.	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family.	0.936
BCL2	EGF	ENSFCAP00000062072	ENSFCAP00000059920	BCL2 apoptosis regulator.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	0.544
BCL2	IGF1R	ENSFCAP00000062072	ENSFCAP00000016299	BCL2 apoptosis regulator.	Tyrosine-protein kinase receptor.	0.538
BCL2	NR3C1	ENSFCAP00000062072	ENSFCAP00000019629	BCL2 apoptosis regulator.	Uncharacterized protein.	0.454
BECN1	BCL2	ENSFCAP00000012183	ENSFCAP00000062072	Beclin 1.	BCL2 apoptosis regulator.	0.999
BECN1	CASP3	ENSFCAP00000012183	ENSFCAP00000031946	Beclin 1.	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family.	0.832
CASP3	BCL2	ENSFCAP00000031946	ENSFCAP00000062072	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family.	BCL2 apoptosis regulator.	0.936
CASP3	BECN1	ENSFCAP00000031946	ENSFCAP00000012183	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family.	Beclin 1.	0.832
CASP3	EGF	ENSFCAP00000031946	ENSFCAP00000059920	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	0.617
CASP3	IGF1R	ENSFCAP00000031946	ENSFCAP00000016299	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family.	Tyrosine-protein kinase receptor.	0.577
EGF	BCL2	ENSFCAP00000059920	ENSFCAP00000062072	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	BCL2 apoptosis regulator.	0.544
EGF	CASP3	ENSFCAP00000059920	ENSFCAP00000031946	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family.	0.617
EGF	IGF1R	ENSFCAP00000059920	ENSFCAP00000016299	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	Tyrosine-protein kinase receptor.	0.954