STRINGSTRING
RPE65 RPE65 ELANE ELANE SELPLG SELPLG CD47 CD47 BCL2 BCL2 VCAM1 VCAM1 CSF2 CSF2 TTR TTR CD4 CD4 SPARC SPARC CCNE1 CCNE1 CCNA2 CCNA2 ALB ALB BMP2 BMP2 TFRC TFRC CCNB1 CCNB1 SELE SELE CD22 CD22 CTSB CTSB CCND1 CCND1 CCR5 CCR5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPE65Retinoid isomerohydrolase RPE65. (628 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (339 aa)
SELPLGUncharacterized protein. (590 aa)
CD47CD47 molecule. (326 aa)
BCL2BCL2 apoptosis regulator. (237 aa)
VCAM1Vascular cell adhesion molecule 1. (748 aa)
CSF2Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. (142 aa)
TTRTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (146 aa)
CD4CD4 molecule. (487 aa)
SPARCSecreted protein acidic and cysteine rich. (303 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (410 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
ALBSerum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] (618 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
TFRCTransferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity); Belongs to the [...] (789 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (600 aa)
SELESelectin E. (638 aa)
CD22CD22 molecule. (845 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (339 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (312 aa)
CCR5G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (352 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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