15 items (Felis catus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

Your Input:
	RHOA	Ras homolog family member A. (193 aa)
	NTF4	Neurotrophin 4; Belongs to the NGF-beta family. (210 aa)
	TIAM1	T cell lymphoma invasion and metastasis 1. (1591 aa)
	NTF3	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa)
	PLD2	Phospholipase. (984 aa)
	NPAS4	Neuronal PAS domain protein 4. (800 aa)
	SORT1	Sortilin. (877 aa)
	JUN	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
	PIK3C3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
	SNCA	Alpha-synuclein; Belongs to the synuclein family. (140 aa)
	LIMK1	LIM domain kinase 1. (763 aa)
	PLD1	Phospholipase. (1074 aa)
	NGF	Nerve growth factor; Belongs to the NGF-beta family. (259 aa)
	BDNF	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (255 aa)
	SORCS2	Sortilin related VPS10 domain containing receptor 2. (1163 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDNF	JUN	ENSFCAP00000049682	ENSFCAP00000021043	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.638
BDNF	LIMK1	ENSFCAP00000049682	ENSFCAP00000034649	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	LIM domain kinase 1.	0.469
BDNF	NGF	ENSFCAP00000049682	ENSFCAP00000045550	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Nerve growth factor; Belongs to the NGF-beta family.	0.805
BDNF	NPAS4	ENSFCAP00000049682	ENSFCAP00000008622	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Neuronal PAS domain protein 4.	0.642
BDNF	NTF3	ENSFCAP00000049682	ENSFCAP00000006367	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family.	0.900
BDNF	NTF4	ENSFCAP00000049682	ENSFCAP00000000238	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Neurotrophin 4; Belongs to the NGF-beta family.	0.937
BDNF	RHOA	ENSFCAP00000049682	ENSFCAP00000017917	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Ras homolog family member A.	0.459
BDNF	SNCA	ENSFCAP00000049682	ENSFCAP00000027235	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Alpha-synuclein; Belongs to the synuclein family.	0.497
BDNF	SORCS2	ENSFCAP00000049682	ENSFCAP00000057402	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Sortilin related VPS10 domain containing receptor 2.	0.585
BDNF	SORT1	ENSFCAP00000049682	ENSFCAP00000014154	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Sortilin.	0.887
JUN	BDNF	ENSFCAP00000021043	ENSFCAP00000049682	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	0.638
LIMK1	BDNF	ENSFCAP00000034649	ENSFCAP00000049682	LIM domain kinase 1.	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	0.469
LIMK1	RHOA	ENSFCAP00000034649	ENSFCAP00000017917	LIM domain kinase 1.	Ras homolog family member A.	0.590
LIMK1	TIAM1	ENSFCAP00000034649	ENSFCAP00000002181	LIM domain kinase 1.	T cell lymphoma invasion and metastasis 1.	0.516
NGF	BDNF	ENSFCAP00000045550	ENSFCAP00000049682	Nerve growth factor; Belongs to the NGF-beta family.	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	0.805
NGF	NTF4	ENSFCAP00000045550	ENSFCAP00000000238	Nerve growth factor; Belongs to the NGF-beta family.	Neurotrophin 4; Belongs to the NGF-beta family.	0.491
NGF	RHOA	ENSFCAP00000045550	ENSFCAP00000017917	Nerve growth factor; Belongs to the NGF-beta family.	Ras homolog family member A.	0.648
NGF	SORCS2	ENSFCAP00000045550	ENSFCAP00000057402	Nerve growth factor; Belongs to the NGF-beta family.	Sortilin related VPS10 domain containing receptor 2.	0.934
NGF	SORT1	ENSFCAP00000045550	ENSFCAP00000014154	Nerve growth factor; Belongs to the NGF-beta family.	Sortilin.	0.823
NPAS4	BDNF	ENSFCAP00000008622	ENSFCAP00000049682	Neuronal PAS domain protein 4.	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	0.642