STRINGSTRING
GABARAP GABARAP STAT3 STAT3 CD4 CD4 MAP1B MAP1B ATG12 ATG12 IFNG IFNG ULK1 ULK1 ATG16L1 ATG16L1 BECN1 BECN1 CD40 CD40 LAMP1 LAMP1 ATG14 ATG14 MAP1LC3A MAP1LC3A MAP1S MAP1S CD40LG CD40LG MAP1A MAP1A ATG7 ATG7 LOC111558925 LOC111558925 MAP1LC3C MAP1LC3C EGFR EGFR ATG3 ATG3 ATG5 ATG5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GABARAPGABA type A receptor-associated protein. (117 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
CD4CD4 molecule. (487 aa)
MAP1BMicrotubule associated protein 1B. (2471 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (167 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1113 aa)
ATG16L1Autophagy related 16 like 1. (623 aa)
BECN1Beclin 1. (448 aa)
CD40CD40 molecule. (324 aa)
LAMP1Lysosomal associated membrane protein 1. (422 aa)
ATG14Autophagy related 14. (510 aa)
MAP1LC3AMicrotubule associated protein 1 light chain 3 alpha. (121 aa)
MAP1SUncharacterized protein. (78 aa)
CD40LGCD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] (260 aa)
MAP1AMicrotubule associated protein 1A. (2991 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (752 aa)
LOC111558925Uncharacterized protein. (968 aa)
MAP1LC3CUncharacterized protein. (141 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
ATG3Autophagy-related protein 3. (333 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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