STRINGSTRING
PINK1 PINK1 SPG7 SPG7 MAOB MAOB GPX5 GPX5 GPX8 GPX8 GPX4 GPX4 SOD2 SOD2 UCHL1 UCHL1 GPX1 GPX1 MANF MANF GPX2 GPX2 GPX3 GPX3 TH TH MAPT MAPT PRKN PRKN MAOA MAOA COMT COMT GPX6 GPX6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PINK1PTEN induced kinase 1. (581 aa)
SPG7SPG7 matrix AAA peptidase subunit, paraplegin. (793 aa)
MAOBAmine oxidase. (520 aa)
GPX5Glutathione peroxidase; Belongs to the glutathione peroxidase family. (222 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
GPX4Glutathione peroxidase; Belongs to the glutathione peroxidase family. (196 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
UCHL1Ubiquitin carboxyl-terminal hydrolase. (347 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (205 aa)
MANFMesencephalic astrocyte derived neurotrophic factor. (181 aa)
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (189 aa)
GPX3Glutathione peroxidase; Belongs to the glutathione peroxidase family. (225 aa)
THInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (557 aa)
MAPTMicrotubule-associated protein. (778 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (462 aa)
MAOAAmine oxidase. (1178 aa)
COMTCatechol-O-methyltransferase. (303 aa)
GPX6Glutathione peroxidase; Belongs to the glutathione peroxidase family. (221 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.