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HMOX1 | Heme oxygenase 1. (404 aa) | ||||
BCL2 | BCL2 apoptosis regulator. (237 aa) | ||||
LOC109498011 | Uncharacterized protein. (483 aa) | ||||
CXCR4 | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] (400 aa) | ||||
LBP | Lipopolysaccharide binding protein. (497 aa) | ||||
IDO2 | Indoleamine 2,3-dioxygenase 2. (410 aa) | ||||
FUCA1 | Alpha-L-fucosidase 1. (721 aa) | ||||
FUCA2 | Alpha-L-fucosidase 2. (470 aa) | ||||
SIRT3 | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (417 aa) | ||||
NFATC1 | Nuclear factor of activated T cells 1. (1085 aa) | ||||
GPX6 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (221 aa) | ||||
CSAD | Cysteine sulfinic acid decarboxylase. (540 aa) | ||||
HSF2 | Heat shock transcription factor 2. (535 aa) | ||||
SOX4 | Transcription factor SOX. (459 aa) | ||||
CCND1 | Cyclin D1; Belongs to the cyclin family. (312 aa) | ||||
KLF2 | Kruppel like factor 2. (362 aa) | ||||
YES1 | Tyrosine-protein kinase. (546 aa) | ||||
ANGPT1 | Angiopoietin 1. (498 aa) | ||||
POU2F1 | POU domain protein. (756 aa) | ||||
SRC | Tyrosine-protein kinase. (678 aa) | ||||
LRG1 | Leucine rich alpha-2-glycoprotein 1. (346 aa) | ||||
TXN | Thioredoxin; Belongs to the thioredoxin family. (105 aa) | ||||
GPX3 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (225 aa) | ||||
GPX2 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (189 aa) | ||||
CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa) | ||||
LOC101095098 | Uncharacterized protein. (617 aa) | ||||
CYP2E2 | Uncharacterized protein; Belongs to the cytochrome P450 family. (495 aa) | ||||
CELF1 | CUGBP Elav-like family member 1. (514 aa) | ||||
NOS2 | Nitric oxide synthase; Produces nitric oxide (NO). (1165 aa) | ||||
FASLG | Tumor necrosis factor ligand superfamily member 6, membrane form; Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T- cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. [FasL intr [...] (280 aa) | ||||
TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) | ||||
GPX1 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (205 aa) | ||||
CASP3 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (302 aa) | ||||
ITGB1 | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (801 aa) | ||||
MPO | Myeloperoxidase. (720 aa) | ||||
CASP9 | Caspase 9; Belongs to the peptidase C14A family. (451 aa) | ||||
CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) | ||||
FOXA1 | Forkhead box A1. (536 aa) | ||||
GPX8 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa) | ||||
RND3 | Rho family GTPase 3. (244 aa) | ||||
AFP | Alpha fetoprotein. (609 aa) | ||||
GOT1 | Aspartate aminotransferase. (413 aa) | ||||
IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (233 aa) | ||||
GPX4 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (196 aa) | ||||
CPEB2 | Cytoplasmic polyadenylation element binding protein 2. (1045 aa) | ||||
RFX7 | Regulatory factor X7. (1369 aa) | ||||
GOT2 | Aspartate aminotransferase. (430 aa) | ||||
DLX2 | Distal-less homeobox 2. (331 aa) | ||||
SOD2 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa) | ||||
TJP1 | Tight junction protein 1; Belongs to the MAGUK family. (2008 aa) | ||||
SIRT1 | Sirtuin 1. (745 aa) | ||||
TWIST1 | Twist family bHLH transcription factor 1. (200 aa) | ||||
ALB | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] (618 aa) | ||||
ZEB1 | Zinc finger E-box binding homeobox 1. (1125 aa) | ||||
MMP9 | Matrix metallopeptidase 9. (705 aa) | ||||
ADIPOQ | Adiponectin, C1Q and collagen domain containing. (283 aa) | ||||
IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (154 aa) | ||||
IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa) | ||||
NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa) | ||||
PDCD4 | Programmed cell death 4. (469 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (167 aa) | ||||
OCLN | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (521 aa) | ||||
CALCR | Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (483 aa) | ||||
NLK | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa) | ||||
GAPDH | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa) | ||||
GAPDHS | Glyceraldehyde-3-phosphate dehydrogenase. (405 aa) | ||||
NRP1 | Neuropilin; Belongs to the neuropilin family. (923 aa) | ||||
IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (302 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
CD4 | CD4 molecule. (487 aa) | ||||
IDO1 | Indoleamine 2,3-dioxygenase 1. (407 aa) | ||||
FAAH | Fatty acid amide hydrolase. (579 aa) | ||||
HIF1A | Hypoxia inducible factor 1 subunit alpha. (825 aa) | ||||
IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (134 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (770 aa) | ||||
HOXB7 | Homeobox B7. (217 aa) | ||||
TXN2 | Thioredoxin 2. (163 aa) | ||||
CCL2 | C-C motif chemokine. (99 aa) | ||||
GPX5 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (222 aa) | ||||
SP1 | Sp1 transcription factor. (786 aa) | ||||
PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) | ||||
ZEB2 | Zinc finger E-box binding homeobox 2. (1217 aa) | ||||
TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |