STRINGSTRING
PRDX4 PRDX4 UQCR10 UQCR10 FLAD1 FLAD1 GSTP1 GSTP1 ETFA ETFA NDUFS4 NDUFS4 CPT1A CPT1A COX4I1 COX4I1 ETFB ETFB ACADVL ACADVL GSR GSR HSPE1 HSPE1 SDHA SDHA TXN TXN MFN1 MFN1 SOD2 SOD2 ND1 ND1 ACADM ACADM DGAT2 DGAT2 NFE2 NFE2 ACADL ACADL ACADS ACADS MMP9 MMP9 POLG POLG CLPP CLPP FASN FASN NOX1 NOX1 GAPDH GAPDH IL1B IL1B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRDX4Peroxiredoxin 4. (306 aa)
UQCR10Ubiquinol-cytochrome c reductase, complex III subunit X. (182 aa)
FLAD1FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. (492 aa)
GSTP1Uncharacterized protein; Belongs to the GST superfamily. (438 aa)
ETFAElectron transfer flavoprotein subunit alpha. (418 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (187 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
COX4I1Cytochrome c oxidase subunit 4I1. (201 aa)
ETFBElectron transfer flavoprotein subunit beta. (255 aa)
ACADVLAcyl-CoA dehydrogenase very long chain. (655 aa)
GSRGlutathione-disulfide reductase. (561 aa)
HSPE1Heat shock protein family E (Hsp10) member 1; Belongs to the GroES chaperonin family. (102 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
MFN1Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (804 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
ND1NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (318 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (445 aa)
DGAT2Uncharacterized protein. (388 aa)
NFE2Nuclear factor, erythroid 2. (373 aa)
ACADLAcyl-CoA dehydrogenase long chain. (430 aa)
ACADSAcyl-CoA dehydrogenase short chain. (412 aa)
MMP9Matrix metallopeptidase 9. (705 aa)
POLGDNA polymerase gamma, catalytic subunit. (1220 aa)
CLPPATP-dependent Clp protease proteolytic subunit. (272 aa)
FASNFatty acid synthase. (2655 aa)
NOX1NADPH oxidase 1. (564 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (302 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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