29 items (Felis catus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

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Your Input:
	EZH2	Enhancer of zeste 2 polycomb repressive complex 2 subunit. (460 aa)
	HTT	Huntingtin. (3140 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	LGR5	Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
	TMPRSS2	Transmembrane serine protease 2; Belongs to the peptidase S1 family. (492 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	SYK	Spleen associated tyrosine kinase. (636 aa)
	KLF4	Kruppel-like factor 4. (485 aa)
	CDX2	Caudal type homeobox 2. (313 aa)
	DCN	Decorin; May affect the rate of fibrils formation. (360 aa)
	RPGR	Uncharacterized protein. (965 aa)
	SST	Somatostatin. (116 aa)
	TLR3	Toll like receptor 3; Belongs to the Toll-like receptor family. (917 aa)
	PPY	Pancreatic icosapeptide; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions; Belongs to the NPY family. (126 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
	NKX2-1	NK2 homeobox 1. (399 aa)
	TSC2	TSC complex subunit 2. (1806 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	CFTR	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1481 aa)
	EGFR	Receptor protein-tyrosine kinase. (1209 aa)
	WNT10B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (518 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	FOXG1	Forkhead box G1. (483 aa)
	TMPRSS4	Transmembrane serine protease 4; Belongs to the peptidase S1 family. (476 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity). (1213 aa)
	PODXL	Podocalyxin like. (594 aa)
	ETV2	ETS variant 2. (249 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCN	EGF	ENSFCAP00000020254	ENSFCAP00000059920	Decorin; May affect the rate of fibrils formation.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	0.469
DCN	EGFR	ENSFCAP00000020254	ENSFCAP00000041464	Decorin; May affect the rate of fibrils formation.	Receptor protein-tyrosine kinase.	0.958
DCN	FGF10	ENSFCAP00000020254	ENSFCAP00000032796	Decorin; May affect the rate of fibrils formation.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.566
DCN	TGFB1	ENSFCAP00000020254	ENSFCAP00000005040	Decorin; May affect the rate of fibrils formation.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.985
DCN	TGFB2	ENSFCAP00000020254	ENSFCAP00000032705	Decorin; May affect the rate of fibrils formation.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.511
DCN	TGFB3	ENSFCAP00000020254	ENSFCAP00000013178	Decorin; May affect the rate of fibrils formation.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.944
EGF	DCN	ENSFCAP00000059920	ENSFCAP00000020254	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	Decorin; May affect the rate of fibrils formation.	0.469
EGF	EGFR	ENSFCAP00000059920	ENSFCAP00000041464	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	Receptor protein-tyrosine kinase.	0.999
EGF	FGF10	ENSFCAP00000059920	ENSFCAP00000032796	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.864
EGF	LGR5	ENSFCAP00000059920	ENSFCAP00000007472	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	Leucine rich repeat containing G protein-coupled receptor 5.	0.610
EGF	NOG	ENSFCAP00000059920	ENSFCAP00000046242	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.765
EGF	TGFB1	ENSFCAP00000059920	ENSFCAP00000005040	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	Transforming growth factor beta; Belongs to the TGF-beta family.	0.625
EGF	TP53	ENSFCAP00000059920	ENSFCAP00000045749	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.676
EGF	WNT3A	ENSFCAP00000059920	ENSFCAP00000035820	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.626
EGFR	DCN	ENSFCAP00000041464	ENSFCAP00000020254	Receptor protein-tyrosine kinase.	Decorin; May affect the rate of fibrils formation.	0.958
EGFR	EGF	ENSFCAP00000041464	ENSFCAP00000059920	Receptor protein-tyrosine kinase.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	0.999
EGFR	EZH2	ENSFCAP00000041464	ENSFCAP00000007988	Receptor protein-tyrosine kinase.	Enhancer of zeste 2 polycomb repressive complex 2 subunit.	0.499
EGFR	FGF10	ENSFCAP00000041464	ENSFCAP00000032796	Receptor protein-tyrosine kinase.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.835
EGFR	LGR5	ENSFCAP00000041464	ENSFCAP00000007472	Receptor protein-tyrosine kinase.	Leucine rich repeat containing G protein-coupled receptor 5.	0.438
EGFR	TGFB1	ENSFCAP00000041464	ENSFCAP00000005040	Receptor protein-tyrosine kinase.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.644