20 items (Felis catus) - STRING interaction network

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	NEFL	Neurofilament light; Belongs to the intermediate filament family. (543 aa)
	HNRNPA2B1	Heterogeneous nuclear ribonucleoprotein A2/B1. (456 aa)
	PRKN	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (462 aa)
	SDHA	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
	LRP6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
	MDH2	Malate dehydrogenase, mitochondrial; Belongs to the LDH/MDH superfamily. MDH type 1 family. (338 aa)
	PINK1	PTEN induced kinase 1. (581 aa)
	HSPA9	Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa)
	AGO2	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (860 aa)
	NCAM1	Neural cell adhesion molecule 1. (1135 aa)
	AIFM1	Apoptosis inducing factor mitochondria associated 1. (613 aa)
	ECHS1	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (324 aa)
	ACO2	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (781 aa)
	KRAS	Uncharacterized protein. (380 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
	MVP	Major vault protein. (892 aa)
	LRP5	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1620 aa)
	SNCA	Alpha-synuclein; Belongs to the synuclein family. (140 aa)
	PRNP	Major prion protein; Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase deg [...] (260 aa)
	XPO5	Exportin 5. (1205 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACO2	ECHS1	ENSFCAP00000015908	ENSFCAP00000014105	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.493
ACO2	HSPA9	ENSFCAP00000015908	ENSFCAP00000001592	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family.	0.688
ACO2	MDH2	ENSFCAP00000015908	ENSFCAP00000000558	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	Malate dehydrogenase, mitochondrial; Belongs to the LDH/MDH superfamily. MDH type 1 family.	0.806
ACO2	SDHA	ENSFCAP00000015908	ENSFCAP00000040603	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.927
AGO2	HNRNPA2B1	ENSFCAP00000002557	ENSFCAP00000048694	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Heterogeneous nuclear ribonucleoprotein A2/B1.	0.454
AGO2	KRAS	ENSFCAP00000002557	ENSFCAP00000016005	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Uncharacterized protein.	0.413
AGO2	PTEN	ENSFCAP00000002557	ENSFCAP00000016216	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.559
AGO2	XPO5	ENSFCAP00000002557	ENSFCAP00000031162	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Exportin 5.	0.922
ECHS1	ACO2	ENSFCAP00000014105	ENSFCAP00000015908	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.493
ECHS1	HSPA9	ENSFCAP00000014105	ENSFCAP00000001592	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.	Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family.	0.430
ECHS1	MDH2	ENSFCAP00000014105	ENSFCAP00000000558	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.	Malate dehydrogenase, mitochondrial; Belongs to the LDH/MDH superfamily. MDH type 1 family.	0.526
HNRNPA2B1	AGO2	ENSFCAP00000048694	ENSFCAP00000002557	Heterogeneous nuclear ribonucleoprotein A2/B1.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.454
HSPA9	ACO2	ENSFCAP00000001592	ENSFCAP00000015908	Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.688
HSPA9	ECHS1	ENSFCAP00000001592	ENSFCAP00000014105	Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family.	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.430
HSPA9	PINK1	ENSFCAP00000001592	ENSFCAP00000000737	Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family.	PTEN induced kinase 1.	0.486
HSPA9	SDHA	ENSFCAP00000001592	ENSFCAP00000040603	Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.548
KRAS	AGO2	ENSFCAP00000016005	ENSFCAP00000002557	Uncharacterized protein.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.413
KRAS	PTEN	ENSFCAP00000016005	ENSFCAP00000016216	Uncharacterized protein.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.786
LRP5	LRP6	ENSFCAP00000024784	ENSFCAP00000000041	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.987
LRP6	LRP5	ENSFCAP00000000041	ENSFCAP00000024784	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.987