8 items (Felis catus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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textmining

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protein homology

Your Input:
	PXDNL	Peroxidasin like. (1457 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	IL1B	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (302 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	MMP1	Matrix metallopeptidase 1. (471 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	PXDN	Peroxidasin. (1502 aa)
	IGF1	Insulin like growth factor 1. (195 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IGF1	IL1B	ENSFCAP00000042016	ENSFCAP00000005482	Insulin like growth factor 1.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.713
IGF1	PXDN	ENSFCAP00000042016	ENSFCAP00000038176	Insulin like growth factor 1.	Peroxidasin.	0.532
IGF1	PXDNL	ENSFCAP00000042016	ENSFCAP00000004944	Insulin like growth factor 1.	Peroxidasin like.	0.532
IGF1	TGFB1	ENSFCAP00000042016	ENSFCAP00000005040	Insulin like growth factor 1.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.741
IGF1	TGFB2	ENSFCAP00000042016	ENSFCAP00000032705	Insulin like growth factor 1.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.622
IL1B	IGF1	ENSFCAP00000005482	ENSFCAP00000042016	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Insulin like growth factor 1.	0.713
IL1B	MMP1	ENSFCAP00000005482	ENSFCAP00000014645	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Matrix metallopeptidase 1.	0.520
IL1B	PXDN	ENSFCAP00000005482	ENSFCAP00000038176	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Peroxidasin.	0.693
IL1B	PXDNL	ENSFCAP00000005482	ENSFCAP00000004944	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Peroxidasin like.	0.693
IL1B	TGFB1	ENSFCAP00000005482	ENSFCAP00000005040	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.777
IL1B	TGFB2	ENSFCAP00000005482	ENSFCAP00000032705	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.458
MMP1	IL1B	ENSFCAP00000014645	ENSFCAP00000005482	Matrix metallopeptidase 1.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.520
MMP1	TGFB1	ENSFCAP00000014645	ENSFCAP00000005040	Matrix metallopeptidase 1.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.521
PXDN	IGF1	ENSFCAP00000038176	ENSFCAP00000042016	Peroxidasin.	Insulin like growth factor 1.	0.532
PXDN	IL1B	ENSFCAP00000038176	ENSFCAP00000005482	Peroxidasin.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.693
PXDN	TGFB1	ENSFCAP00000038176	ENSFCAP00000005040	Peroxidasin.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.521
PXDNL	IGF1	ENSFCAP00000004944	ENSFCAP00000042016	Peroxidasin like.	Insulin like growth factor 1.	0.532
PXDNL	IL1B	ENSFCAP00000004944	ENSFCAP00000005482	Peroxidasin like.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.693
PXDNL	TGFB1	ENSFCAP00000004944	ENSFCAP00000005040	Peroxidasin like.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.521
TGFB1	IGF1	ENSFCAP00000005040	ENSFCAP00000042016	Transforming growth factor beta; Belongs to the TGF-beta family.	Insulin like growth factor 1.	0.741