STRINGSTRING
FURIN FURIN LOC101091046 LOC101091046 LRP1 LRP1 PLD2 PLD2 GAPDH GAPDH DPH1 DPH1 PXDNL PXDNL EEF2 EEF2 PLD1 PLD1 DPH5 DPH5 PXDN PXDN CLIP1 CLIP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (877 aa)
LOC101091046Uncharacterized protein. (1716 aa)
LRP1LDL receptor related protein 1. (4561 aa)
PLD2Phospholipase. (984 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa)
DPH12-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (445 aa)
PXDNLPeroxidasin like. (1457 aa)
EEF2Eukaryotic translation elongation factor 2. (858 aa)
PLD1Phospholipase. (1074 aa)
DPH5Diphthamide biosynthesis 5. (279 aa)
PXDNPeroxidasin. (1502 aa)
CLIP1CAP-Gly domain containing linker protein 1. (1438 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (16%) [HD]