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CYP1A2 CYP1A2 DHRS3 DHRS3 HSD17B6 HSD17B6 RETSAT RETSAT PNPLA4 PNPLA4 BCO1 BCO1 ADH5 ADH5 CYP26A1 CYP26A1 DGAT1 DGAT1 ALDH1A1 ALDH1A1 RDH8 RDH8 CYP26C1 CYP26C1 ALDH1A3 ALDH1A3 CYP2S1 CYP2S1 CYP27C1 CYP27C1 RDH5 RDH5 RDH16 RDH16 SDR16C5 SDR16C5 UGT1A UGT1A RDH10 RDH10 LOC101100387 LOC101100387 LRAT LRAT AOX1 AOX1 ENSFCAP00000027010 ENSFCAP00000027010 DHRS9 DHRS9 AWAT2 AWAT2 LOC105259649 LOC105259649 CYP3A131 CYP3A131 LOC101094994 LOC101094994 LOC105260134 LOC105260134 ALDH1A2 ALDH1A2 CYP26B1 CYP26B1 RPE65 RPE65 RDH12 RDH12 LOC101083281 LOC101083281 LOC101087662 LOC101087662 RDH11 RDH11
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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CYP1A2Cytochrome P450 1A2; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E [...] (512 aa)
DHRS3Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
HSD17B6Hydroxysteroid 17-beta dehydrogenase 6; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
RETSATRetinol saturase. (610 aa)
PNPLA4Patatin like phospholipase domain containing 4. (290 aa)
BCO1Beta-carotene oxygenase 1. (546 aa)
ADH5S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
CYP26A1Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (501 aa)
DGAT1O-acyltransferase. (493 aa)
ALDH1A1Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family. (501 aa)
RDH8Retinol dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (522 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
CYP2S1Cytochrome P450 family 2 subfamily S member 1; Belongs to the cytochrome P450 family. (493 aa)
CYP27C1Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (580 aa)
RDH5Retinol dehydrogenase 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (331 aa)
RDH16Retinol dehydrogenase 16; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (344 aa)
SDR16C5Short chain dehydrogenase/reductase family 16C member 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (326 aa)
UGT1AUDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (533 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
LOC101100387PKS_ER domain-containing protein. (375 aa)
LRATLecithin retinol acyltransferase. (484 aa)
AOX1Uncharacterized protein. (1324 aa)
ENSFCAP00000027010Uncharacterized protein. (425 aa)
DHRS9Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa)
AWAT2Acyl-CoA wax alcohol acyltransferase 2. (341 aa)
LOC105259649Uncharacterized protein; Belongs to the cytochrome P450 family. (552 aa)
CYP3A131Uncharacterized protein. (503 aa)
LOC101094994Uncharacterized protein; Belongs to the cytochrome P450 family. (510 aa)
LOC105260134Uncharacterized protein; Belongs to the cytochrome P450 family. (498 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (549 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
RPE65Retinoid isomerohydrolase RPE65. (628 aa)
RDH12Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (322 aa)
LOC101083281Uncharacterized protein. (480 aa)
LOC101087662UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family. (555 aa)
RDH11Retinol dehydrogenase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (426 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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