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ELOVL5 ELOVL5 MECR MECR ACADSB ACADSB ACSL1 ACSL1 ACSBG1 ACSBG1 CPT1C CPT1C HSD17B8 HSD17B8 EHHADH EHHADH HSD17B4 HSD17B4 HACD3 HACD3 FASN FASN ACSL3 ACSL3 MCAT MCAT FADS1 FADS1 HACD1 HACD1 HADHA HADHA HADHB HADHB ECHS1 ECHS1 ACOX3 ACOX3 ACOX1 ACOX1 SCP2 SCP2 ACADS ACADS CBR4 CBR4 ACADL ACADL FADS2 FADS2 PPT1 PPT1 SCD5 SCD5 ACADM ACADM HACD4 HACD4 ELOVL4 ELOVL4 CPT1B CPT1B ACSL4 ACSL4 ACACA ACACA ELOVL6 ELOVL6 CPT2 CPT2 ACSL6 ACSL6 HACD2 HACD2 ELOVL1 ELOVL1 HTD2 HTD2 ACADVL ACADVL ACAA2 ACAA2 OXSM OXSM ACSL5 ACSL5 ACAA1 ACAA1 CPT1A CPT1A LOC102900010 LOC102900010 PPT2 PPT2 ACAT2 ACAT2 ALKBH3 ALKBH3 ACAT1 ACAT1 ELOVL2 ELOVL2 HADH HADH ACSF3 ACSF3
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ELOVL5Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (299 aa)
MECRMitochondrial trans-2-enoyl-CoA reductase. (374 aa)
ACADSBAcyl-CoA dehydrogenase short/branched chain. (432 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (698 aa)
ACSBG1Acyl-CoA synthetase bubblegum family member 1. (815 aa)
CPT1CCarnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (803 aa)
HSD17B8Hydroxysteroid 17-beta dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (285 aa)
EHHADHEnoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (806 aa)
HSD17B4Hydroxysteroid 17-beta dehydrogenase 4. (736 aa)
HACD3Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (362 aa)
FASNFatty acid synthase. (2655 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (720 aa)
MCATMalonyl-CoA-acyl carrier protein transacylase. (383 aa)
FADS1Fatty acid desaturase 1. (360 aa)
HACD1Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (288 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
HADHBHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (475 aa)
ECHS1Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (324 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (700 aa)
ACOX1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (661 aa)
SCP2Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (551 aa)
ACADSAcyl-CoA dehydrogenase short chain. (412 aa)
CBR4Carbonyl reductase 4. (237 aa)
ACADLAcyl-CoA dehydrogenase long chain. (430 aa)
FADS2Fatty acid desaturase 2. (444 aa)
PPT1Palmitoyl-protein thioesterase 1. (289 aa)
SCD5Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (330 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (445 aa)
HACD4Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (232 aa)
ELOVL4Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (314 aa)
CPT1BCarnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (711 aa)
ACACAAcetyl-CoA carboxylase alpha. (2385 aa)
ELOVL6Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa)
CPT2Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (696 aa)
ACSL6AMP-binding domain-containing protein. (722 aa)
HACD2Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (344 aa)
ELOVL1Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (287 aa)
HTD2Hydroxyacyl-thioester dehydratase type 2. (167 aa)
ACADVLAcyl-CoA dehydrogenase very long chain. (655 aa)
ACAA2Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
OXSM3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (460 aa)
ACSL5Acyl-CoA synthetase long chain family member 5. (670 aa)
ACAA1Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (456 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
LOC102900010AMP-binding domain-containing protein. (758 aa)
PPT2Palmitoyl-protein thioesterase 2. (309 aa)
ACAT2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
ALKBH3Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (361 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (517 aa)
ELOVL2Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (305 aa)
HADHHydroxyacyl-CoA dehydrogenase. (338 aa)
ACSF3Acyl-CoA synthetase family member 3. (586 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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