STRINGSTRING
PYCR3 PYCR3 ALDOB ALDOB ALDH18A1 ALDH18A1 GPT2 GPT2 PFKL PFKL IDH1 IDH1 MTR MTR SDSL SDSL GAPDH GAPDH ASL ASL BCAT2 BCAT2 RPIA RPIA PAH PAH IDH3A IDH3A OTC OTC TKTL1 TKTL1 MAT1A MAT1A MAT2A MAT2A CS CS PRPS2 PRPS2 CTH CTH PYCR1 PYCR1 PGK1 PGK1 PFKM PFKM ARG2 ARG2 ALDOA ALDOA SHMT1 SHMT1 GOT1L1 GOT1L1 ACO2 ACO2 LOC101081229 LOC101081229 PSPH PSPH LOC101081589 LOC101081589 NAGS NAGS PGAM2 PGAM2 ASS1 ASS1 IDH2 IDH2 PGK2 PGK2 PSAT1 PSAT1 GOT1 GOT1 TKT TKT ASNS ASNS GPT GPT TPI1 TPI1 GOT2 GOT2 TKTL2 TKTL2 ENSFCAP00000031759 ENSFCAP00000031759 ENO2 ENO2 ENO3 ENO3 SDS SDS ENO1 ENO1 PC PC ALDOC ALDOC ENO4 ENO4 PGAM1 PGAM1 CPS1 CPS1 RPE RPE PKLR PKLR PRPS1 PRPS1 MAT2B MAT2B PYCR2 PYCR2 ACO1 ACO1 GLUL GLUL BCAT1 BCAT1 IDH3B IDH3B PFKP PFKP TALDO1 TALDO1 ARG1 ARG1 CBS CBS PRPS1L1 PRPS1L1 SHMT2 SHMT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PYCR3Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (274 aa)
ALDOBFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
ALDH18A1Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (797 aa)
GPT2Glutamic--pyruvic transaminase 2. (680 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
MTRMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1214 aa)
SDSLSerine dehydratase like. (329 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa)
ASLUncharacterized protein. (477 aa)
BCAT2Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (404 aa)
RPIARibose 5-phosphate isomerase A. (311 aa)
PAHPhenylalanine hydroxylase. (465 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
OTCOrnithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (354 aa)
TKTL1Transketolase like 1. (629 aa)
MAT1AS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (396 aa)
MAT2AS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (395 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (466 aa)
PRPS2Phosphoribosyl pyrophosphate synthetase 2. (318 aa)
CTHCystathionine gamma-lyase. (405 aa)
PYCR1F420_oxidored domain-containing protein. (450 aa)
PGK1Phosphoglycerate kinase. (454 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (859 aa)
ARG2Arginase. (354 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (469 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
GOT1L1Glutamic-oxaloacetic transaminase 1 like 1. (406 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (781 aa)
LOC101081229Pyruvate kinase; Belongs to the pyruvate kinase family. (353 aa)
PSPHPhosphoserine phosphatase. (276 aa)
LOC101081589Beta_elim_lyase domain-containing protein. (395 aa)
NAGSN-acetylglutamate synthase. (531 aa)
PGAM2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa)
ASS1Argininosuccinate synthase 1. (412 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (451 aa)
PGK2Phosphoglycerate kinase. (417 aa)
PSAT1Phosphoserine aminotransferase. (370 aa)
GOT1Aspartate aminotransferase. (413 aa)
TKTTransketolase. (714 aa)
ASNSAsparagine synthetase [glutamine-hydrolyzing]. (561 aa)
GPTGlutamic--pyruvic transaminase. (496 aa)
TPI1Triosephosphate isomerase. (286 aa)
GOT2Aspartate aminotransferase. (430 aa)
TKTL2Transketolase like 2. (626 aa)
ENSFCAP00000031759PFK domain-containing protein. (208 aa)
ENO2Enolase 2. (434 aa)
ENO3Enolase 3. (495 aa)
SDSSerine dehydratase. (328 aa)
ENO1Enolase 1. (522 aa)
PCPyruvate carboxylase. (1236 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
ENO4Enolase 4. (612 aa)
PGAM1Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (332 aa)
CPS1Carbamoyl-phosphate synthase 1. (1513 aa)
RPEUncharacterized protein. (239 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (634 aa)
PRPS1Pribosyltran_N domain-containing protein. (318 aa)
MAT2BMethionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (334 aa)
PYCR2Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (320 aa)
ACO1Aconitase 1; Belongs to the aconitase/IPM isomerase family. (889 aa)
GLULGlutamine synthetase. (506 aa)
BCAT1Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (457 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (404 aa)
PFKPUncharacterized protein. (753 aa)
TALDO1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (386 aa)
ARG1Arginase. (329 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (633 aa)
PRPS1L1Uncharacterized protein. (115 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (542 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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