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| | ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1208 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1405 aa) |
| | TIAM1 | T cell lymphoma invasion and metastasis 1. (1591 aa) |
| | TEK | TEK receptor tyrosine kinase. (1125 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | ITGA2B | Integrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1086 aa) |
| | KIT | Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (979 aa) |
| | F2R | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa) |
| | CTNNB1 | Catenin beta 1. (783 aa) |
| | CSF1R | Macrophage colony-stimulating factor 1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulat [...] (1213 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1131 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | PFN4 | Profilin; Belongs to the profilin family. (129 aa) |
| | ID1 | Inhibitor of DNA binding 1, HLH protein. (154 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | VAV1 | Vav guanine nucleotide exchange factor 1. (846 aa) |
| | ITGAM | Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1173 aa) |
| | ADCY4 | Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1010 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (342 aa) |
| | CALML6 | Calmodulin like 6. (180 aa) |
| | PLCE1 | Phosphoinositide phospholipase C. (2301 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa) |
| | CALML4 | Calmodulin like 4. (196 aa) |
| | ACTG1 | Actin gamma 1. (375 aa) |
| | GNAI2 | G protein subunit alpha i2. (436 aa) |
| | SIPA1L1 | Signal induced proliferation associated 1 like 1. (1803 aa) |
| | GNAI1 | G protein subunit alpha i1. (354 aa) |
| | SIPA1L2 | Signal induced proliferation associated 1 like 2. (1717 aa) |
| | TLN2 | Talin 2. (2542 aa) |
| | FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | VASP | Vasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (383 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa) |
| | FYB1 | FYN binding protein 1. (837 aa) |
| | LPAR3 | Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (383 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | PARD6A | Par-6 family cell polarity regulator alpha. (345 aa) |
| | MAGI1 | Membrane associated guanylate kinase, WW and PDZ domain containing 1. (1446 aa) |
| | RASGRP3 | RAS guanyl releasing protein 3. (692 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1514 aa) |
| | EPHA2 | EPH receptor A2. (936 aa) |
| | PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (885 aa) |
| | CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (569 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (725 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | PFN1 | Profilin; Belongs to the profilin family. (140 aa) |
| | THBS1 | Thrombospondin 1. (1170 aa) |
| | VAV2 | Vav guanine nucleotide exchange factor 2. (878 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (784 aa) |
| | DOCK4 | Dedicator of cytokinesis 4; Belongs to the DOCK family. (1970 aa) |
| | TLN1 | Talin 1. (2558 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (804 aa) |
| | P2RY1 | Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (374 aa) |
| | MAP2K2 | Protein kinase domain-containing protein. (549 aa) |
| | GRIN2A | Glutamate ionotropic receptor NMDA type subunit 2A. (1464 aa) |
| | ANGPT2 | Angiopoietin 2. (494 aa) |
| | SIPA1L3 | Signal induced proliferation associated 1 like 3. (1776 aa) |
| | LPAR2 | Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (351 aa) |
| | PDGFB | Platelet-derived growth factor subunit B; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers wit [...] (245 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | PRKD3 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (891 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (830 aa) |
| | LOC102900772 | Uncharacterized protein. (247 aa) |
| | KRAS | Uncharacterized protein. (380 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1367 aa) |
| | SIPA1 | Signal-induced proliferation-associated 1. (1047 aa) |
| | CALM2 | Calmodulin 2; Belongs to the calmodulin family. (149 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | KRIT1 | KRIT1 ankyrin repeat containing. (736 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | RALA | RAS like proto-oncogene A. (206 aa) |
| | LPAR1 | Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | RALB | RAS like proto-oncogene B. (206 aa) |
| | LOC101101369 | Uncharacterized protein; Belongs to the profilin family. (152 aa) |
| | RRAS | RAS related. (218 aa) |
| | RAP1A | RAP1A, member of RAS oncogene family. (184 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | ADORA2A | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | ANGPT4 | Angiopoietin 4. (499 aa) |
| | PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3. (1544 aa) |
| | CDC42-2 | Uncharacterized protein. (191 aa) |
| | GNAQ | G protein subunit alpha q. (359 aa) |
| | RAP1B | RAP1B, member of RAS oncogene family. (187 aa) |
| | PRKCI | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the PP2C family. (698 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (930 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa) |
| | CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) |
| | GNAI3 | G protein subunit alpha i3. (354 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa) |
| | LOC101097703 | EF-hand domain-containing protein; Belongs to the calmodulin family. (86 aa) |
| | EVL | Enah/Vasp-like. (461 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1381 aa) |
| | MAGI3 | Membrane associated guanylate kinase, WW and PDZ domain containing 3. (1482 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (367 aa) |
| | ITGB1 | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (801 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (852 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (784 aa) |
| | HGF | Hepatocyte growth factor alpha chain; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity). (728 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | RAP1GAP | RAP1 GTPase activating protein. (807 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa) |
| | RAPGEF4 | Rap guanine nucleotide exchange factor 4. (1011 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | RAPGEF3 | Rap guanine nucleotide exchange factor 3. (923 aa) |
| | RAPGEF1 | Rap guanine nucleotide exchange factor 1. (1270 aa) |
| | ITGB2 | Integrin beta. (867 aa) |
| | MRAS | Muscle RAS oncogene homolog. (254 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa) |
| | SRC | Tyrosine-protein kinase. (678 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1209 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | CTNND1 | Catenin delta 1. (962 aa) |
| | EFNA5 | Ephrin A5; Belongs to the ephrin family. (228 aa) |
| | IGF1 | Insulin like growth factor 1. (195 aa) |
| | PFN2 | Profilin; Belongs to the profilin family. (188 aa) |
| | LCP2 | Lymphocyte cytosolic protein 2. (534 aa) |
| | EFNA4 | Ephrin RBD domain-containing protein; Belongs to the ephrin family. (314 aa) |
| | RALGDS | Uncharacterized protein. (885 aa) |
| | PIK3R2 | Phosphoinositide-3-kinase regulatory subunit 2. (726 aa) |
| | ENSFCAP00000043586 | Uncharacterized protein. (261 aa) |
| | APBB1IP | Amyloid beta precursor protein binding family B member 1 interacting protein. (659 aa) |
| | FGFR3 | Fibroblast growth factor receptor. (805 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) |
| | NGFR | Nerve growth factor receptor. (421 aa) |
| | RASGRP2 | RAS guanyl releasing protein 2. (615 aa) |
| | PARD6B | Par-6 family cell polarity regulator beta. (370 aa) |
| | RAPGEF2 | Rap guanine nucleotide exchange factor 2. (1700 aa) |
| | GRIN2B | Glutamate ionotropic receptor NMDA type subunit 2B. (1486 aa) |
| | FGF5 | Fibroblast growth factor 5. (279 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (304 aa) |
| | NGF | Nerve growth factor; Belongs to the NGF-beta family. (259 aa) |
| | PGF | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa) |
| | VAV3 | Vav guanine nucleotide exchange factor 3. (875 aa) |
| | PIK3R3 | Uncharacterized protein. (461 aa) |
| | ANGPT1 | Angiopoietin 1. (498 aa) |
| | FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (229 aa) |
| | MAGI2 | Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1452 aa) |
| | EFNA2 | Ephrin A2; Belongs to the ephrin family. (263 aa) |
| | ENAH | ENAH actin regulator. (856 aa) |
| | PARD6G | Par-6 family cell polarity regulator gamma. (363 aa) |
| | BCAR1 | BCAR1 scaffold protein, Cas family member. (889 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (326 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (245 aa) |
| | RASSF5 | Ras association domain family member 5. (425 aa) |
| | CDH1 | Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (881 aa) |
| | EFNA3 | Ephrin RBD domain-containing protein; Belongs to the ephrin family. (237 aa) |
| | SKAP1 | Src kinase associated phosphoprotein 1. (398 aa) |
| | PDGFD | Platelet derived growth factor D. (380 aa) |
| | GNAS | GNAS complex locus. (968 aa) |
| | FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (285 aa) |
| | PARD3 | Par-3 family cell polarity regulator. (1417 aa) |
| | F2RL3 | F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (401 aa) |
| | LPAR5 | Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (373 aa) |
| | FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (271 aa) |
| | PRKCZ | Protein kinase C zeta. (649 aa) |
| | PLCG1 | Phosphoinositide phospholipase C. (1391 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1209 aa) |
| | ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1135 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1245 aa) |
| | GRIN1 | Glutamate ionotropic receptor NMDA type subunit 1. (1008 aa) |
| | ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1148 aa) |
| | RAPGEF6 | Uncharacterized protein. (1623 aa) |
| | RAC2 | Rac family small GTPase 2. (234 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) |
| | AFDN | Afadin, adherens junction formation factor. (1873 aa) |
| | LOC111559549 | Ig-like domain-containing protein. (247 aa) |
| | ADCY5 | Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1329 aa) |
| | RAPGEF5 | Rap guanine nucleotide exchange factor 5. (889 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase. (571 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity). (1213 aa) |
| | KITLG | Soluble KIT ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity). (274 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (841 aa) |
| | MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1382 aa) |
| | MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (383 aa) |
| | ITGAL | Integrin subunit alpha L; Belongs to the integrin alpha chain family. (1290 aa) |
| | GNAO1 | G protein subunit alpha o1. (370 aa) |
