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PRKCG PRKCG ITPR1 ITPR1 PLCD4 PLCD4 ITPR2 ITPR2 INPPL1 INPPL1 PLCD3 PLCD3 PIP5K1A PIP5K1A CALML6 CALML6 PLCE1 PLCE1 CALML4 CALML4 SACM1L SACM1L INPP5B INPP5B PIK3R1 PIK3R1 PRKCB PRKCB INPP5D INPP5D MTMR7 MTMR7 PRKCA PRKCA DGKQ DGKQ ITPR3 ITPR3 CDIPT CDIPT MTMR14 MTMR14 PIK3C2B PIK3C2B DGKK DGKK PLCZ1 PLCZ1 PTEN PTEN CALM2 CALM2 PIP4P1 PIP4P1 IP6K2 IP6K2 ITPKB ITPKB PPIP5K2 PPIP5K2 ITPKC ITPKC CDS2 CDS2 MTM1 MTM1 PI4K2B PI4K2B ITPKA ITPKA CDS1 CDS1 PIK3CD PIK3CD DGKE DGKE IPMK IPMK PIK3C3 PIK3C3 MTMR3 MTMR3 IP6K1 IP6K1 PIK3CB PIK3CB CALML3 CALML3 LOC101097703 LOC101097703 INPP4B INPP4B PI4KB PI4KB DGKB DGKB PIP4K2A PIP4K2A PIKFYVE PIKFYVE DGKG DGKG PIK3C2G PIK3C2G PIK3C2A PIK3C2A MTMR4 MTMR4 PLCB2 PLCB2 PIK3CA PIK3CA OCRL OCRL MTMR2 MTMR2 DGKA DGKA INPP1 INPP1 IMPAD1 IMPAD1 PLCB1 PLCB1 PLCG2 PLCG2 PIP5K1B PIP5K1B INPP5F INPP5F PIK3R2 PIK3R2 ENSFCAP00000043586 ENSFCAP00000043586 PIP4P2 PIP4P2 DGKI DGKI PIP4K2B PIP4K2B PIK3R3 PIK3R3 DGKH DGKH IP6K3 IP6K3 SYNJ2 SYNJ2 DGKZ DGKZ IMPA1 IMPA1 MTMR8 MTMR8 SYNJ1 SYNJ1 INPP5A INPP5A ITPK1 ITPK1 PLCD1 PLCD1 INPP4A INPP4A BICD2 BICD2 PLCG1 PLCG1 PLCB4 PLCB4 PI4K2A PI4K2A PLCB3 PLCB3 PI4KA PI4KA DGKD DGKD MTMR1 MTMR1 INPP5E INPP5E PIP4K2C PIP4K2C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2757 aa)
PLCD4Phosphoinositide phospholipase C. (800 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1264 aa)
PLCD3Phosphoinositide phospholipase C. (777 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (550 aa)
CALML6Calmodulin like 6. (180 aa)
PLCE1Phosphoinositide phospholipase C. (2301 aa)
CALML4Calmodulin like 4. (196 aa)
SACM1LSAC1 like phosphatidylinositide phosphatase. (587 aa)
INPP5BInositol polyphosphate-5-phosphatase B. (913 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1181 aa)
MTMR7Myotubularin related protein 7. (660 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (784 aa)
DGKQDiacylglycerol kinase. (942 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
CDIPTCDP-diacylglycerol--inositol 3-phosphatidyltransferase. (213 aa)
MTMR14Myotubularin related protein 14. (648 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1634 aa)
DGKKDiacylglycerol kinase. (1254 aa)
PLCZ1Phospholipase C zeta 1. (169 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (149 aa)
PIP4P1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (298 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (425 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (933 aa)
PPIP5K2Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1277 aa)
ITPKCKinase; Belongs to the inositol phosphokinase (IPK) family. (667 aa)
CDS2Phosphatidate cytidylyltransferase; Belongs to the CDS family. (488 aa)
MTM1Myotubularin 1. (603 aa)
PI4K2BPhosphatidylinositol 4-kinase type 2 beta. (485 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (461 aa)
CDS1Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (461 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
DGKEDiacylglycerol kinase. (564 aa)
IPMKKinase; Belongs to the inositol phosphokinase (IPK) family. (425 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
MTMR3Myotubularin related protein 3. (1222 aa)
IP6K1Kinase; Belongs to the inositol phosphokinase (IPK) family. (441 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
LOC101097703EF-hand domain-containing protein; Belongs to the calmodulin family. (86 aa)
INPP4BInositol polyphosphate-4-phosphatase type II B. (939 aa)
PI4KBPhosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family. (861 aa)
DGKBDiacylglycerol kinase. (820 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (421 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2189 aa)
DGKGDiacylglycerol kinase. (790 aa)
PIK3C2GPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1486 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1688 aa)
MTMR4Myotubularin related protein 4. (1209 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
OCRLOCRL inositol polyphosphate-5-phosphatase. (987 aa)
MTMR2Myotubularin related protein 2. (643 aa)
DGKADiacylglycerol kinase. (734 aa)
INPP1Inositol polyphosphate-1-phosphatase. (402 aa)
IMPAD1Inositol monophosphatase domain containing 1. (360 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1318 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (548 aa)
INPP5FInositol polyphosphate-5-phosphatase F. (1133 aa)
PIK3R2Phosphoinositide-3-kinase regulatory subunit 2. (726 aa)
ENSFCAP00000043586Uncharacterized protein. (261 aa)
PIP4P2Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
DGKIDiacylglycerol kinase. (1082 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa)
PIK3R3Uncharacterized protein. (461 aa)
DGKHDiacylglycerol kinase. (1220 aa)
IP6K3Kinase; Belongs to the inositol phosphokinase (IPK) family. (497 aa)
SYNJ2Synaptojanin 2. (1484 aa)
DGKZDiacylglycerol kinase. (1119 aa)
IMPA1Inositol-1-monophosphatase. (318 aa)
MTMR8Uncharacterized protein. (107 aa)
SYNJ1Synaptojanin 1. (1562 aa)
INPP5AInositol polyphosphate-5-phosphatase A. (475 aa)
ITPK1Inositol-tetrakisphosphate 1-kinase. (461 aa)
PLCD1Phosphoinositide phospholipase C. (801 aa)
INPP4AInositol polyphosphate-4-phosphatase type I A. (994 aa)
BICD2BICD cargo adaptor 2. (1267 aa)
PLCG1Phosphoinositide phospholipase C. (1391 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1209 aa)
PI4K2API3K/PI4K domain-containing protein. (481 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1245 aa)
PI4KAPhosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family. (2139 aa)
DGKDDiacylglycerol kinase. (1222 aa)
MTMR1Myotubularin related protein 1. (732 aa)
INPP5EInositol polyphosphate-5-phosphatase E. (720 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (435 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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