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| | DEGS1 | Delta 4-desaturase, sphingolipid 1. (336 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa) |
| | SGPL1 | Sphingosine-1-phosphate lyase 1. (671 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (558 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (467 aa) |
| | ACER2 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (606 aa) |
| | NXNL2 | Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (623 aa) |
| | SPTLC1 | Serine palmitoyltransferase long chain base subunit 1. (473 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | SPHK1 | Sphingosine kinase 1. (473 aa) |
| | SMPD2 | Sphingomyelin phosphodiesterase 2. (424 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (444 aa) |
| | S1PR1 | Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (353 aa) |
| | GNAI2 | G protein subunit alpha i2. (436 aa) |
| | S1PR4 | Sphingosine-1-phosphate receptor 4; Belongs to the G-protein coupled receptor 1 family. (385 aa) |
| | GNAI1 | G protein subunit alpha i1. (354 aa) |
| | GAB2 | GRB2 associated binding protein 2. (678 aa) |
| | CERS3 | Ceramide synthase 3. (387 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (989 aa) |
| | CTSD | Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (408 aa) |
| | NSMAF | Neutral sphingomyelinase activation associated factor. (920 aa) |
| | PLD2 | Phospholipase. (984 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1366 aa) |
| | ABCC1 | ATP binding cassette subfamily C member 1. (1486 aa) |
| | CERS5 | Ceramide synthase 5. (392 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (725 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (784 aa) |
| | PPP2R5B | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (606 aa) |
| | S1PR2 | Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (352 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa) |
| | MAP2K2 | Protein kinase domain-containing protein. (549 aa) |
| | SGMS1 | Sphingomyelin synthase 1. (407 aa) |
| | FCER1A | Fc fragment of IgE receptor Ia. (263 aa) |
| | ASAH1 | N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (397 aa) |
| | KRAS | Uncharacterized protein. (380 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | PPP2R3B | Protein phosphatase 2 regulatory subunit B''beta. (579 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | ADORA3 | Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (318 aa) |
| | DEGS2 | Delta 4-desaturase, sphingolipid 2. (446 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | SMPD1 | Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (619 aa) |
| | PPP2R2D | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (488 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | SGPP2 | Sphingosine-1-phosphate phosphatase 2. (399 aa) |
| | GNA13 | G protein subunit alpha 13. (377 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | ASAH2 | Neutral ceramidase. (771 aa) |
| | PPP2R3C | Protein phosphatase 2 regulatory subunit B''gamma. (453 aa) |
| | GNAQ | G protein subunit alpha q. (359 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the PP2C family. (698 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | GNAI3 | G protein subunit alpha i3. (354 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (583 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (367 aa) |
| | BDKRB2 | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (392 aa) |
| | ADORA1 | Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | SPTLC3 | Serine palmitoyltransferase long chain base subunit 3. (552 aa) |
| | SGMS2 | Sphingomyelin synthase 2. (365 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (678 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1355 aa) |
| | PLD1 | Phospholipase. (1074 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | FCER1G | Fc fragment of IgE receptor Ig. (86 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | PPP2R3A | Protein phosphatase 2 regulatory subunit B''alpha. (1150 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | SPHK2 | DAGKc domain-containing protein. (660 aa) |
| | PIK3R2 | Phosphoinositide-3-kinase regulatory subunit 2. (726 aa) |
| | CERS6 | Ceramide synthase 6. (392 aa) |
| | TRADD | TNFRSF1A associated via death domain. (311 aa) |
| | PIK3R3 | Uncharacterized protein. (461 aa) |
| | CERS2 | Ceramide synthase 2. (533 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (555 aa) |
| | GNA12 | G protein subunit alpha 12. (382 aa) |
| | SGPP1 | Sphingosine-1-phosphate phosphatase 1. (635 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (321 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa) |
| | PPP2R5E | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa) |
| | LOC101101505 | Uncharacterized protein. (259 aa) |
| | PRKCZ | Protein kinase C zeta. (649 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1209 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1245 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (205 aa) |
| | LOC102902042 | Uncharacterized protein. (243 aa) |
| | RAC2 | Rac family small GTPase 2. (234 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (772 aa) |
| | KNG1 | Kininogen 1. (644 aa) |
| | ROCK2 | Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1471 aa) |
| | PPP2R5A | Protein phosphatase 2 regulatory subunit B'alpha. (642 aa) |
| | CERS4 | Ceramide synthase 4. (592 aa) |
| | LOC102902259-2 | Uncharacterized protein. (238 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase. (571 aa) |
| | SPTLC2 | Serine palmitoyltransferase long chain base subunit 2. (694 aa) |
| | S1PR5 | Sphingosine-1-phosphate receptor 5. (398 aa) |
| | PPP2R2C | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (488 aa) |
| | LOC102902189 | Uncharacterized protein. (236 aa) |
| | BCL2 | BCL2 apoptosis regulator. (237 aa) |
