STRINGSTRING
SEC24B SEC24B CRYAA CRYAA BAX BAX SAR1B SAR1B LMAN1L LMAN1L TRAF2 TRAF2 CALR CALR DNAJB12 DNAJB12 EDEM1 EDEM1 DDOST DDOST SEL1L2 SEL1L2 VCP VCP HYOU1 HYOU1 UGGT1 UGGT1 DDIT3 DDIT3 MAPK10 MAPK10 EDEM2 EDEM2 UGGT2 UGGT2 ERO1B ERO1B ERN1 ERN1 UFD1 UFD1 HSPA1L HSPA1L RNF5 RNF5 PRKCSH PRKCSH PREB PREB CASP12 CASP12 EIF2AK2 EIF2AK2 SEC31B SEC31B PDIA3 PDIA3 SEC24D SEC24D MOGS MOGS HSPH1 HSPH1 HSPA2 HSPA2 MAP3K5 MAP3K5 RPN1 RPN1 STUB1 STUB1 PDIA4 PDIA4 HSPA4L HSPA4L AMFR AMFR GANAB GANAB UBXN1 UBXN1 SEL1L SEL1L PDIA6 PDIA6 ATF4 ATF4 SLC29A1 SLC29A1 SEC24C SEC24C RRBP1 RRBP1 HSPA5 HSPA5 DNAJB11 DNAJB11 NFE2L2 NFE2L2 SEC61B SEC61B EIF2AK3 EIF2AK3 MAN1C1 MAN1C1 NPLOC4 NPLOC4 ERLEC1 ERLEC1 UBQLN1 UBQLN1 ATF6B ATF6B MAN1A2 MAN1A2 BAG1 BAG1 SEC23A SEC23A RAD23B RAD23B UBQLN3 UBQLN3 DNAJC3 DNAJC3 ATXN3 ATXN3 CRYAB CRYAB UBE2D2 UBE2D2 SEC62 SEC62 HERPUD1 HERPUD1 EIF2S1 EIF2S1 EIF2AK4 EIF2AK4 RAD23A RAD23A SSR3 SSR3 UBXN4 UBXN4 TRAM1 TRAM1 STT3B STT3B RBX1 RBX1 ERP29 ERP29 ERO1A ERO1A DERL2 DERL2 DNAJA2 DNAJA2 DAD1 DAD1 SELENOS SELENOS DERL1 DERL1 CUL1 CUL1 UBQLN2 UBQLN2 P4HB P4HB EIF2AK1 EIF2AK1 SYVN1 SYVN1 UBE2J1 UBE2J1 PLAA PLAA DNAJB1 DNAJB1 DNAJA1 DNAJA1 SEC61A2 SEC61A2 CKAP4 CKAP4 SEC31A SEC31A SEC24A SEC24A SEC61G SEC61G DNAJC5 DNAJC5 ENSFCAP00000034476 ENSFCAP00000034476 EDEM3 EDEM3 MBTPS2 MBTPS2 HSPA8 HSPA8 MAPK8 MAPK8 TXNDC5 TXNDC5 UBXN8 UBXN8 CAPN1 CAPN1 CANX CANX NGLY1 NGLY1 HSP90AA1 HSP90AA1 XBP1 XBP1 DERL3 DERL3 LOC111557571 LOC111557571 SEC13 SEC13 PRKN PRKN SAR1A SAR1A BAG2 BAG2 RNF185 RNF185 PPP1R15A PPP1R15A SSR2 SSR2 MAP2K7 MAP2K7 SUMO3 SUMO3 TUSC3 TUSC3 MAPK9 MAPK9 UBXN6 UBXN6 RPN2 RPN2 FBXO2 FBXO2 WFS1 WFS1 ATF6 ATF6 UBE2J2 UBE2J2 DNAJB2 DNAJB2 DNAJC5B DNAJC5B FBXO6 FBXO6 SEC63 SEC63 STT3A STT3A DNAJC10 DNAJC10 NSFL1C NSFL1C SEC61A1 SEC61A1 SIL1 SIL1 MARCHF6 MARCHF6 SSR1 SSR1 UBQLN4 UBQLN4 MXD3 MXD3 UBE2G1 UBE2G1 CAPN2 CAPN2 CPLX4 CPLX4 HSP90B1 HSP90B1 SVIP SVIP UBXN2A UBXN2A HSPBP1 HSPBP1 SKP1 SKP1 SEC23B SEC23B DNAJC1 DNAJC1 MAN1A1 MAN1A1 C1orf116 C1orf116 BCL2 BCL2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SEC24BSEC24 homolog B, COPII coat complex component. (1259 aa)
CRYAAAlpha-crystallin A chain; Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA. (173 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
SAR1BSecretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
LMAN1LLectin, mannose binding 1 like. (527 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa)
CALRCalreticulin. (417 aa)
DNAJB12DnaJ heat shock protein family (Hsp40) member B12. (478 aa)
EDEM1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (653 aa)
DDOSTDolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] (456 aa)
SEL1L2SEL1L2 adaptor subunit of ERAD E3 ligase. (685 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (761 aa)
HYOU1Hypoxia up-regulated 1. (999 aa)
UGGT1UDP-glucose glycoprotein glucosyltransferase 1. (1556 aa)
DDIT3DNA damage inducible transcript 3. (167 aa)
MAPK10Mitogen-activated protein kinase. (467 aa)
EDEM2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (592 aa)
UGGT2UDP-glucose glycoprotein glucosyltransferase 2. (1509 aa)
ERO1BEndoplasmic reticulum oxidoreductase 1 beta. (523 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (972 aa)
UFD1Ubiquitin recognition factor in ER associated degradation 1. (307 aa)
HSPA1LHeat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa)
RNF5Ring finger protein 5. (180 aa)
PRKCSHProtein kinase C substrate 80K-H. (538 aa)
PREBProlactin regulatory element binding. (418 aa)
CASP12Uncharacterized protein; Belongs to the peptidase C14A family. (527 aa)
EIF2AK2Eukaryotic translation initiation factor 2 alpha kinase 2. (541 aa)
SEC31BSEC31 homolog B, COPII coat complex component. (1176 aa)
PDIA3Protein disulfide-isomerase. (505 aa)
SEC24DSEC24 homolog D, COPII coat complex component. (1074 aa)
MOGSMannosyl-oligosaccharide glucosidase. (836 aa)
HSPH1Heat shock protein family H (Hsp110) member 1. (859 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (639 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1366 aa)
RPN1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (607 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
PDIA4Protein disulfide-isomerase A4. (645 aa)
HSPA4LHeat shock protein family A (Hsp70) member 4 like. (840 aa)
AMFRAutocrine motility factor receptor. (781 aa)
GANABGlucosidase II alpha subunit; Belongs to the glycosyl hydrolase 31 family. (966 aa)
UBXN1UBX domain protein 1. (296 aa)
SEL1LSEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (795 aa)
PDIA6Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family. (440 aa)
ATF4Activating transcription factor 4. (352 aa)
SLC29A1Heat shock protein 90 alpha family class B member 1. (740 aa)
SEC24CSEC24 homolog C, COPII coat complex component. (1096 aa)
RRBP1Ribosome binding protein 1. (1524 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
DNAJB11J domain-containing protein. (358 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (606 aa)
SEC61BProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1114 aa)
MAN1C1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (633 aa)
NPLOC4NPL4 homolog, ubiquitin recognition factor. (608 aa)
ERLEC1Endoplasmic reticulum lectin 1. (483 aa)
UBQLN1Ubiquilin 1. (591 aa)
ATF6BActivating transcription factor 6 beta. (628 aa)
MAN1A2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (623 aa)
BAG1BCL2 associated athanogene 1. (315 aa)
SEC23AProtein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (765 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (408 aa)
UBQLN3Ubiquilin 3. (654 aa)
DNAJC3DnaJ heat shock protein family (Hsp40) member C3. (504 aa)
ATXN3Josephin domain-containing protein. (382 aa)
CRYABCrystallin alpha B; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
SEC62SEC62 homolog, preprotein translocation factor. (400 aa)
HERPUD1Homocysteine inducible ER protein with ubiquitin like domain 1. (393 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1653 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (362 aa)
SSR3Signal sequence receptor subunit 3. (185 aa)
UBXN4UBX domain protein 4. (507 aa)
TRAM1Translocating chain-associated membrane protein; Belongs to the TRAM family. (374 aa)
STT3BSTT3 oligosaccharyltransferase complex catalytic subunit B. (826 aa)
RBX1Ring-box 1. (108 aa)
ERP29Endoplasmic reticulum protein 29. (345 aa)
ERO1AEndoplasmic reticulum oxidoreductase 1 alpha. (468 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
DNAJA2DnaJ heat shock protein family (Hsp40) member A2. (412 aa)
DAD1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (113 aa)
SELENOSSelenoprotein S. (188 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa)
CUL1Cullin 1; Belongs to the cullin family. (829 aa)
UBQLN2Ubiquilin 2. (815 aa)
P4HBProtein disulfide-isomerase. (510 aa)
EIF2AK1Eukaryotic translation initiation factor 2 alpha kinase 1. (641 aa)
SYVN1Synoviolin 1. (612 aa)
UBE2J1Ubiquitin conjugating enzyme E2 J1. (318 aa)
PLAAPhospholipase A2 activating protein. (796 aa)
DNAJB1DnaJ heat shock protein family (Hsp40) member B1. (340 aa)
DNAJA1DnaJ heat shock protein family (Hsp40) member A1. (397 aa)
SEC61A2SEC61 translocon alpha 2 subunit. (476 aa)
CKAP4Cytoskeleton associated protein 4. (586 aa)
SEC31ASEC31 homolog A, COPII coat complex component. (1265 aa)
SEC24ASEC24 homolog A, COPII coat complex component. (1099 aa)
SEC61GUncharacterized protein. (68 aa)
DNAJC5DnaJ heat shock protein family (Hsp40) member C5. (198 aa)
ENSFCAP00000034476J domain-containing protein. (143 aa)
EDEM3alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (947 aa)
MBTPS2Membrane bound transcription factor peptidase, site 2. (519 aa)
HSPA8Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (667 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
TXNDC5Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family. (436 aa)
UBXN8UBX domain protein 8. (276 aa)
CAPN1Calpain 1; Belongs to the peptidase C2 family. (828 aa)
CANXCalnexin. (637 aa)
NGLY1N-glycanase 1. (654 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (753 aa)
XBP1X-box binding protein 1. (383 aa)
DERL3Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (245 aa)
LOC111557571alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (703 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (368 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (462 aa)
SAR1ASecretion associated Ras related GTPase 1A; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
BAG2BCL2 associated athanogene 2. (211 aa)
RNF185Ring finger protein 185. (192 aa)
PPP1R15AProtein phosphatase 1 regulatory subunit 15A. (685 aa)
SSR2Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. (183 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (435 aa)
SUMO3Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (289 aa)
TUSC3Tumor suppressor candidate 3. (406 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
UBXN6UBX domain protein 6. (502 aa)
RPN2Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (647 aa)
FBXO2F-box protein 2. (297 aa)
WFS1Wolframin ER transmembrane glycoprotein. (888 aa)
ATF6Activating transcription factor 6. (669 aa)
UBE2J2UBIQUITIN_CONJUGAT_2 domain-containing protein. (259 aa)
DNAJB2DnaJ heat shock protein family (Hsp40) member B2. (325 aa)
DNAJC5BDnaJ heat shock protein family (Hsp40) member C5 beta. (211 aa)
FBXO6F-box protein 6. (358 aa)
SEC63SEC63 homolog, protein translocation regulator. (793 aa)
STT3ASTT3 oligosaccharyltransferase complex catalytic subunit A. (710 aa)
DNAJC10DnaJ heat shock protein family (Hsp40) member C10. (785 aa)
NSFL1CNSFL1 cofactor. (470 aa)
SEC61A1SEC61 translocon alpha 1 subunit. (520 aa)
SIL1SIL1 nucleotide exchange factor. (519 aa)
MARCHF6Membrane associated ring-CH-type finger 6. (910 aa)
SSR1Signal sequence receptor subunit 1. (320 aa)
UBQLN4Ubiquilin 4. (608 aa)
MXD3Lectin, mannose binding 2. (415 aa)
UBE2G1Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (334 aa)
CAPN2Calpain 2; Belongs to the peptidase C2 family. (725 aa)
CPLX4Lectin, mannose binding 1. (611 aa)
HSP90B1Heat shock protein 90 beta family member 1. (809 aa)
SVIPUncharacterized protein. (124 aa)
UBXN2AUBX domain protein 2A. (265 aa)
HSPBP1HSPA (Hsp70) binding protein 1. (374 aa)
SKP1Uncharacterized protein; Belongs to the SKP1 family. (168 aa)
SEC23BProtein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (804 aa)
DNAJC1DnaJ heat shock protein family (Hsp40) member C1. (587 aa)
MAN1A1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (774 aa)
C1orf116Chromosome 1 open reading frame 116. (728 aa)
BCL2BCL2 apoptosis regulator. (237 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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