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CACNG7 CACNG7 COX5B COX5B UQCRC1 UQCRC1 LOC101086703 LOC101086703 CACNA1F CACNA1F CACNA1S CACNA1S UQCRC2 UQCRC2 TPM4 TPM4 MYH6 MYH6 ATP1B1 ATP1B1 SLC9A1 SLC9A1 CACNG3 CACNG3 CYC1 CYC1 TPM2 TPM2 ATP1A3 ATP1A3 SLC9A6 SLC9A6 ACTC1 ACTC1 COX7A1 COX7A1 COX8A COX8A COX4I2 COX4I2 TNNC1 TNNC1 ATP1B3 ATP1B3 CACNG2 CACNG2 CACNG8 CACNG8 UQCRQ UQCRQ CACNG5 CACNG5 UQCRFS1 UQCRFS1 SLC8A2 SLC8A2 ATP2A2 ATP2A2 M3XDY9_FELCA M3XDY9_FELCA CASQ2 CASQ2 COX1 COX1 COX2 COX2 COX3 COX3 CYTB CYTB CACNA1C CACNA1C CACNG4 CACNG4 LOC102899183 LOC102899183 CACNA2D4 CACNA2D4 LOC101100266 LOC101100266 ATP1A1 ATP1A1 LOC101096876 LOC101096876 COX7B COX7B CACNB4 CACNB4 CACNA2D1 CACNA2D1 COX7B2 COX7B2 ENSFCAP00000038072 ENSFCAP00000038072 SLC8A3 SLC8A3 CACNG1 CACNG1 SLC8A1 SLC8A1 TPM3 TPM3 CACNB2 CACNB2 ATP2A1 ATP2A1 LOC105261211 LOC105261211 LOC101095773 LOC101095773 ATP1B4 ATP1B4 SLC9A7 SLC9A7 MYL3 MYL3 CACNG6 CACNG6 ATP2A3 ATP2A3 COX4I1 COX4I1 LOC101095032 LOC101095032 CACNA1D CACNA1D RYR2 RYR2 HRC HRC MYL2 MYL2 MYL4 MYL4 CACNA2D3 CACNA2D3 CACNA2D2 CACNA2D2 ATP1A4 ATP1A4 FXYD2 FXYD2 UQCRB UQCRB LOC101081808 LOC101081808 UQCR10 UQCR10
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
COX5BCytochrome c oxidase subunit 5B. (129 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (481 aa)
LOC101086703Uncharacterized protein. (56 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1984 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1871 aa)
UQCRC2Ubiquinol-cytochrome c reductase core protein 2; Belongs to the peptidase M16 family. (453 aa)
TPM4Tropomyosin 4; Belongs to the tropomyosin family. (284 aa)
MYH6Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (759 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
CYC1Cytochrome c1. (325 aa)
TPM2Tropomyosin 2; Belongs to the tropomyosin family. (284 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
SLC9A6Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (701 aa)
ACTC1Actin alpha cardiac muscle 1. (616 aa)
COX7A1Cytochrome c oxidase subunit 7A1. (80 aa)
COX8ACytochrome c oxidase subunit 8A. (69 aa)
COX4I2Cytochrome c oxidase subunit 4I2. (182 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (161 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (422 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (324 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
ATP2A2Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Isoform SERCA2A is involved in the regulation of the contraction/relaxation cycle. Acts as a regulator of TNFSF11-mediated Ca(2+) signaling pathways via its interaction with TMEM64 which is critical for the TNFSF11-induced CREB1 activation and mitochondrial ROS generation necessary for proper osteoclast generation. Association between TMEM64 and SERCA2 in the ER leads to cytos [...] (1006 aa)
M3XDY9_FELCAUncharacterized protein. (92 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (409 aa)
COX1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (514 aa)
COX2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (227 aa)
COX3Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (261 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2187 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
LOC102899183Uncharacterized protein. (63 aa)
CACNA2D4Calcium voltage-gated channel auxiliary subunit alpha2delta 4. (1123 aa)
LOC101100266Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (86 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1038 aa)
LOC101096876COX6C domain-containing protein. (75 aa)
COX7BCytochrome c oxidase subunit 7B. (80 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (519 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa)
COX7B2Cytochrome c oxidase subunit 7B2. (79 aa)
ENSFCAP00000038072Uncharacterized protein. (92 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa)
SLC8A1Sodium/calcium exchanger 1; Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to Ca(2+) transport during excitation- contraction coupling in muscle. In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum. SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels r [...] (973 aa)
TPM3Tropomyosin 3; Belongs to the tropomyosin family. (334 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (632 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1049 aa)
LOC105261211Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (88 aa)
LOC101095773Cytochrome c oxidase subunit 6A, mitochondrial. (109 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (357 aa)
SLC9A7Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (727 aa)
MYL3Myosin light chain 3. (196 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (262 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (999 aa)
COX4I1Cytochrome c oxidase subunit 4I1. (201 aa)
LOC101095032Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (91 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2216 aa)
RYR2Ryanodine receptor 2. (4967 aa)
HRCHistidine rich calcium binding protein. (788 aa)
MYL2Myosin light chain 2. (174 aa)
MYL4Myosin light chain 4. (228 aa)
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (1091 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1156 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1074 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
UQCRBUbiquinol-cytochrome c reductase binding protein. (137 aa)
LOC101081808Uncharacterized protein. (154 aa)
UQCR10Ubiquinol-cytochrome c reductase, complex III subunit X. (182 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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