STRINGSTRING
WNT1 WNT1 AREG AREG CRB1 CRB1 SCRIB SCRIB TEAD2 TEAD2 WNT8A WNT8A CTNNA1 CTNNA1 CTNNB1 CTNNB1 PPP2R1A PPP2R1A SMAD1 SMAD1 NF2 NF2 BMP5 BMP5 ID1 ID1 FZD6 FZD6 CRB2 CRB2 TGFB1 TGFB1 SERPINE1 SERPINE1 AJUBA AJUBA ACTG1 ACTG1 DVL1 DVL1 DVL3 DVL3 PARD6A PARD6A MPP5 MPP5 PPP1CC PPP1CC TP73 TP73 YWHAB YWHAB WNT3 WNT3 AMOT AMOT FZD9 FZD9 TEAD3 TEAD3 RASSF6 RASSF6 BIRC3 BIRC3 BMPR2 BMPR2 TGFB3 TGFB3 LLGL1 LLGL1 SNAI2 SNAI2 PPP1CA PPP1CA YWHAZ YWHAZ PATJ PATJ LIMD1 LIMD1 WNT7B WNT7B WNT11 WNT11 CTNNA3 CTNNA3 FZD2 FZD2 PPP2CB PPP2CB FZD1 FZD1 PPP2R2D PPP2R2D AFP AFP ID2 ID2 FZD3 FZD3 LATS1 LATS1 AXIN2 AXIN2 WNT16 WNT16 BMPR1A BMPR1A GDF6 GDF6 BMP6 BMP6 PRKCI PRKCI AXIN1 AXIN1 FZD7 FZD7 YWHAG YWHAG WNT2 WNT2 PPP2R2B PPP2R2B WTIP WTIP BMP2 BMP2 SMAD4 SMAD4 FZD4 FZD4 SAV1 SAV1 FZD10 FZD10 GDF5 GDF5 WNT3A WNT3A WWTR1 WWTR1 DLG4 DLG4 DLG5 DLG5 LOC101101321 LOC101101321 TCF7L1 TCF7L1 PPP1CB PPP1CB BIRC5 BIRC5 ITGB2 ITGB2 FRMD6 FRMD6 PPP2CA PPP2CA LOC101095098 LOC101095098 CCND3 CCND3 APC APC BMPR1B BMPR1B WNT10A WNT10A RASSF1 RASSF1 BTRC BTRC APC2 APC2 WNT10B WNT10B CCND2 CCND2 SMAD7 SMAD7 TEAD1 TEAD1 GSK3B GSK3B PARD6B PARD6B CSNK1D CSNK1D TEAD4 TEAD4 MYC MYC WNT2B WNT2B BBC3 BBC3 WNT9A WNT9A DVL2 DVL2 PARD6G PARD6G TGFBR1 TGFBR1 YWHAH YWHAH WNT7A WNT7A YWHAE YWHAE LEF1 LEF1 DLG2 DLG2 WNT6 WNT6 FBXW11 FBXW11 WNT4 WNT4 CDH1 CDH1 YAP1 YAP1 TCF7L2 TCF7L2 BMP8B BMP8B MOB1B MOB1B NKD1 NKD1 DLG1 DLG1 PPP2R2A PPP2R2A FRMD1 FRMD1 BMP4 BMP4 CCND1 CCND1 GDF7 GDF7 LOC111559734 LOC111559734 CCN2 CCN2 FZD5 FZD5 PARD3 PARD3 NKD2 NKD2 CTNNA2 CTNNA2 GLI2 GLI2 PRKCZ PRKCZ AMH AMH WNT5B WNT5B PPP2R1B PPP2R1B SMAD2 SMAD2 YWHAQ YWHAQ WWC1 WWC1 LATS2 LATS2 STK3 STK3 WNT5A WNT5A PPP2R2C PPP2R2C LLGL2 LLGL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
AREGAmphiregulin. (323 aa)
CRB1Crumbs cell polarity complex component 1. (1405 aa)
SCRIBScribble planar cell polarity protein. (1637 aa)
TEAD2TEA domain transcription factor 2. (451 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa)
CTNNA1Catenin alpha 1. (927 aa)
CTNNB1Catenin beta 1. (783 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (606 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
NF2Neurofibromin 2. (596 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (154 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
CRB2Crumbs cell polarity complex component 2. (1283 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
AJUBAAjuba LIM protein. (548 aa)
ACTG1Actin gamma 1. (375 aa)
DVL1Dishevelled segment polarity protein 1. (700 aa)
DVL3Dishevelled segment polarity protein 3. (718 aa)
PARD6APar-6 family cell polarity regulator alpha. (345 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (749 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
AMOTAngiomotin. (1075 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
TEAD3Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (435 aa)
RASSF6Ras association domain family member 6. (413 aa)
BIRC3Baculoviral IAP repeat containing 3. (624 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
LLGL1LLGL scribble cell polarity complex component 1. (1064 aa)
SNAI2Uncharacterized protein. (268 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa)
PATJPATJ crumbs cell polarity complex component. (1872 aa)
LIMD1LIM domains containing 1. (673 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
CTNNA3Catenin alpha 3. (895 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
FZD1Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (652 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (488 aa)
AFPAlpha fetoprotein. (609 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
LATS1Large tumor suppressor kinase 1. (1127 aa)
AXIN2Axin 2. (841 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (475 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
GDF6TGF_BETA_2 domain-containing protein. (462 aa)
BMP6Bone morphogenetic protein 6. (502 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
AXIN1Axin 1. (867 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (289 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (583 aa)
WTIPWT1 interacting protein. (433 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (540 aa)
SAV1Salvador family WW domain containing protein 1. (395 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
GDF5Growth differentiation factor 5. (499 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (797 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1921 aa)
LOC101101321Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (457 aa)
TCF7L1Transcription factor 7 like 1. (586 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (333 aa)
BIRC5Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] (142 aa)
ITGB2Integrin beta. (867 aa)
FRMD6FERM domain containing 6. (622 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
LOC101095098Uncharacterized protein. (617 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (292 aa)
APCAPC regulator of WNT signaling pathway. (2874 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (588 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (416 aa)
RASSF1Ras association domain family member 1. (344 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
APC2APC regulator of WNT signaling pathway 2. (2289 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
TEAD1TEA domain transcription factor 1. (436 aa)
GSK3BProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (433 aa)
PARD6BPar-6 family cell polarity regulator beta. (370 aa)
CSNK1DCasein kinase 1 delta. (488 aa)
TEAD4TEA domain transcription factor 4. (694 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (439 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
BBC3Uncharacterized protein. (193 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
DVL2Dishevelled segment polarity protein 2. (735 aa)
PARD6GPar-6 family cell polarity regulator gamma. (363 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta. (69 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
LEF1Lymphoid enhancer binding factor 1. (415 aa)
DLG2Discs large MAGUK scaffold protein 2. (1012 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
FBXW11F-box and WD repeat domain containing 11. (563 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
CDH1Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (881 aa)
YAP1Yes associated protein 1. (498 aa)
TCF7L2Transcription factor 7 like 2. (673 aa)
BMP8BTGF_BETA_2 domain-containing protein. (402 aa)
MOB1BMOB kinase activator 1B. (221 aa)
NKD1NKD inhibitor of WNT signaling pathway 1. (529 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa)
FRMD1FERM domain-containing protein. (628 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (312 aa)
GDF7Growth differentiation factor 7. (455 aa)
LOC111559734Bone morphogenetic protein 7. (426 aa)
CCN2Cellular communication network factor 2. (477 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (590 aa)
PARD3Par-3 family cell polarity regulator. (1417 aa)
NKD2NKD inhibitor of WNT signaling pathway 2. (488 aa)
CTNNA2Catenin alpha 2. (953 aa)
GLI2Uncharacterized protein. (161 aa)
PRKCZProtein kinase C zeta. (649 aa)
AMHAnti-Mullerian hormone. (800 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (443 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (772 aa)
SMAD2Mothers against decapentaplegic homolog. (721 aa)
YWHAQTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (301 aa)
WWC1WW and C2 domain containing 1. (1077 aa)
LATS2Non-specific serine/threonine protein kinase. (1095 aa)
STK3Serine/threonine kinase 3. (573 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (457 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (488 aa)
LLGL2LLGL scribble cell polarity complex component 2. (1023 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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