STRINGSTRING
PVR PVR CLDN18 CLDN18 CLDN20 CLDN20 ITGA8 ITGA8 CLDN16 CLDN16 CD4 CD4 CLDN6 CLDN6 CLDN9 CLDN9 CLDN4 CLDN4 ITGAM ITGAM SDC1 SDC1 ITGB7 ITGB7 CNTN2 CNTN2 ITGB8 ITGB8 ALCAM ALCAM SIGLEC1 SIGLEC1 OCLN OCLN MADCAM1 MADCAM1 L1CAM L1CAM NLGN1 NLGN1 CD274 CD274 PDCD1LG2 PDCD1LG2 ICAM1 ICAM1 CD80 CD80 LOC101090518 LOC101090518 ITGA4 ITGA4 VCAM1 VCAM1 VSIR VSIR CNTNAP1 CNTNAP1 LOC101095096 LOC101095096 LOC101087918 LOC101087918 CD6 CD6 CD40 CD40 CD28 CD28 CLDN2 CLDN2 CADM3 CADM3 LOC105260551 LOC105260551 LRRC4C LRRC4C CLDN7 CLDN7 CLDN17 CLDN17 CLDN5 CLDN5 ICAM3 ICAM3 NLGN2 NLGN2 SDC4 SDC4 CD226 CD226 NCAM2 NCAM2 CLDN11 CLDN11 CLDN25 CLDN25 CLDN8 CLDN8 LOC101087815 LOC101087815 LRRC4B LRRC4B JAM3 JAM3 NECTIN2 NECTIN2 LOC101099296 LOC101099296 CD8B CD8B LOC101080790 LOC101080790 CDH2 CDH2 CDH3 CDH3 MAG MAG NLGN3 NLGN3 MPZL1 MPZL1 ITGB1 ITGB1 JAM2 JAM2 SDC3 SDC3 CLDN14 CLDN14 CD40LG CD40LG MPZ MPZ CLDN1 CLDN1 SLC26A3-2 SLC26A3-2 CNTN1 CNTN1 NEO1 NEO1 ITGA6 ITGA6 NECTIN3 NECTIN3 CD276 CD276 NFASC NFASC ITGB2 ITGB2 LOC101082653 LOC101082653 NRCAM NRCAM NLGN4X NLGN4X ESAM ESAM LOC101084962 LOC101084962 CTLA4 CTLA4 LOC101090265 LOC101090265 VTCN1 VTCN1 SELE SELE SELL SELL CD99L2 CD99L2 NEGR1 NEGR1 F11R F11R CLDN23 CLDN23 CNTNAP2 CNTNAP2 LOC111558970 LOC111558970 FLAI-K FLAI-K LOC101082906 LOC101082906 PDCD1 PDCD1 TIGIT TIGIT CDH5 CDH5 CD22 CD22 NRXN2 NRXN2 CLDN3 CLDN3 LOC101090771 LOC101090771 ICAM2 ICAM2 NRXN3 NRXN3 NCAM1 NCAM1 CDH1 CDH1 ITGAV ITGAV LOC111560444 LOC111560444 LOC111556177 LOC111556177 NRXN1 NRXN1 LOC101084108 LOC101084108 PECAM1 PECAM1 CLDN15 CLDN15 PTPRM PTPRM LOC101094232 LOC101094232 SELP SELP VCAN VCAN SELPLG SELPLG SDC2 SDC2 ICOSLG ICOSLG LOC111556169 LOC111556169 CD99 CD99 CD8A CD8A LOC111559549 LOC111559549 CD86 CD86 ITGA9 ITGA9 LOC111560443 LOC111560443 SPN SPN CLDN19 CLDN19 CD58 CD58 ICOS ICOS PTPRF PTPRF ITGAL ITGAL LRRC4 LRRC4 CD34 CD34 GLG1 GLG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PVRPVR cell adhesion molecule. (380 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
CLDN20Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1062 aa)
CLDN16Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa)
CD4CD4 molecule. (487 aa)
CLDN6Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa)
CLDN9Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1173 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (797 aa)
CNTN2Contactin 2. (1103 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (767 aa)
ALCAMActivated leukocyte cell adhesion molecule. (583 aa)
SIGLEC1Sialic acid binding Ig like lectin 1. (1720 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (521 aa)
MADCAM1Mucosal vascular addressin cell adhesion molecule 1. (380 aa)
L1CAML1 cell adhesion molecule. (1340 aa)
NLGN1Neuroligin 1. (823 aa)
CD274CD274 molecule. (297 aa)
PDCD1LG2Programmed cell death 1 ligand 2. (302 aa)
ICAM1Intercellular adhesion molecule 1. (532 aa)
CD80B-lymphocyte activation antigen B7-1 (CD80). (292 aa)
LOC101090518Ig-like domain-containing protein; Belongs to the MHC class II family. (250 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1036 aa)
VCAM1Vascular cell adhesion molecule 1. (748 aa)
VSIRV-set immunoregulatory receptor. (311 aa)
CNTNAP1Contactin associated protein 1. (1381 aa)
LOC101095096Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
LOC101087918Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
CD6CD6 molecule. (678 aa)
CD40CD40 molecule. (324 aa)
CD28T-cell-specific surface glycoprotein CD28; Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation. (255 aa)
CLDN2Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa)
CADM3Cell adhesion molecule 3. (430 aa)
LOC105260551Ig-like domain-containing protein; Belongs to the MHC class I family. (438 aa)
LRRC4CLeucine rich repeat containing 4C. (640 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
CLDN17Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
ICAM3Intercellular adhesion molecule 3. (552 aa)
NLGN2Neuroligin 2. (834 aa)
SDC4Syndecan 4. (201 aa)
CD226CD226 molecule. (332 aa)
NCAM2Neural cell adhesion molecule 2. (837 aa)
CLDN11Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
CLDN25Claudin 25. (228 aa)
CLDN8Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (227 aa)
LOC101087815Uncharacterized protein. (219 aa)
LRRC4BLeucine rich repeat containing 4B. (715 aa)
JAM3Junctional adhesion molecule 3. (310 aa)
NECTIN2Nectin cell adhesion molecule 2. (539 aa)
LOC101099296Ig-like domain-containing protein; Belongs to the MHC class I family. (357 aa)
CD8BT-cell surface glycoprotein CD8 beta chain; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src [...] (219 aa)
LOC101080790MHC_I-like_Ag-recog domain-containing protein. (216 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
CDH3Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins. (831 aa)
MAGMyelin associated glycoprotein. (626 aa)
NLGN3Neuroligin 3. (781 aa)
MPZL1Myelin protein zero like 1. (269 aa)
ITGB1Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (801 aa)
JAM2Junctional adhesion molecule 2. (298 aa)
SDC3Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (665 aa)
CLDN14Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (238 aa)
CD40LGCD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] (260 aa)
MPZIg-like domain-containing protein. (247 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
SLC26A3-2Ig-like domain-containing protein; Belongs to the MHC class II family. (254 aa)
CNTN1Contactin 1. (1018 aa)
NEO1Neogenin 1. (1480 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
NECTIN3Nectin cell adhesion molecule 3. (549 aa)
CD276CD276 molecule. (669 aa)
NFASCNeurofascin. (1469 aa)
ITGB2Integrin beta. (867 aa)
LOC101082653Ig-like domain-containing protein. (276 aa)
NRCAMNeuronal cell adhesion molecule. (1211 aa)
NLGN4XCOesterase domain-containing protein. (836 aa)
ESAMEndothelial cell adhesion molecule. (401 aa)
LOC101084962Ig-like domain-containing protein. (253 aa)
CTLA4Cytotoxic T-lymphocyte associated protein 4. (268 aa)
LOC101090265Ig-like domain-containing protein. (263 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (282 aa)
SELESelectin E. (638 aa)
SELLSelectin L. (394 aa)
CD99L2CD99 molecule like 2. (215 aa)
NEGR1Neuronal growth regulator 1. (354 aa)
F11RJunctional adhesion molecule A; Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration. Involved in platelet activation. (Microbial infection) In case of orthoreovirus infection, serves as rec [...] (378 aa)
CLDN23Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (291 aa)
CNTNAP2Contactin associated protein like 2. (1331 aa)
LOC111558970Ig-like domain-containing protein; Belongs to the MHC class II family. (254 aa)
FLAI-KIg-like domain-containing protein; Belongs to the MHC class I family. (406 aa)
LOC101082906Ig-like domain-containing protein. (282 aa)
PDCD1Programmed cell death 1. (278 aa)
TIGITT cell immunoreceptor with Ig and ITIM domains. (312 aa)
CDH5Uncharacterized protein. (402 aa)
CD22CD22 molecule. (845 aa)
NRXN2Neurexin 2. (1714 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
LOC101090771Ig-like domain-containing protein; Belongs to the MHC class II family. (257 aa)
ICAM2Intercellular adhesion molecule 2. (268 aa)
NRXN3Neurexin 3. (1664 aa)
NCAM1Neural cell adhesion molecule 1. (1135 aa)
CDH1Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (881 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1047 aa)
LOC111560444Ig-like domain-containing protein; Belongs to the MHC class II family. (250 aa)
LOC111556177Ig-like domain-containing protein; Belongs to the MHC class I family. (499 aa)
NRXN1Neurexin 1. (1507 aa)
LOC101084108Ig-like domain-containing protein; Belongs to the MHC class II family. (344 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (764 aa)
CLDN15Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (226 aa)
PTPRMProtein tyrosine phosphatase receptor type M. (1511 aa)
LOC101094232Ig-like domain-containing protein; Belongs to the MHC class I family. (461 aa)
SELPSelectin P. (901 aa)
VCANVersican. (3383 aa)
SELPLGUncharacterized protein. (590 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (210 aa)
ICOSLGIg-like domain-containing protein. (356 aa)
LOC111556169Ig-like domain-containing protein. (276 aa)
CD99Uncharacterized protein. (219 aa)
CD8AT-cell surface glycoprotein CD8 alpha chain; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Sr [...] (248 aa)
LOC111559549Ig-like domain-containing protein. (247 aa)
CD86B-lymphocyte activation antigen B7-2 (CD86). (332 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1083 aa)
LOC111560443Ig-like domain-containing protein; Belongs to the MHC class II family. (322 aa)
SPNUncharacterized protein. (532 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (263 aa)
CD58Uncharacterized protein. (270 aa)
ICOSInducible T cell costimulator. (247 aa)
PTPRFProtein tyrosine phosphatase receptor type F. (2147 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1290 aa)
LRRC4Leucine rich repeat containing 4. (633 aa)
CD34CD34 molecule. (406 aa)
GLG1Golgi glycoprotein 1. (1250 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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