STRINGSTRING
CTNNA1 CTNNA1 CTNNB1 CTNNB1 PTPN1 PTPN1 PTPN6 PTPN6 PTPRJ PTPRJ EP300 EP300 CREBBP CREBBP ACTG1 ACTG1 NLK NLK CSNK2B CSNK2B WASF2 WASF2 WASF3 WASF3 SNAI1 SNAI1 FER FER SNAI2 SNAI2 WAS WAS IGF1R IGF1R SSX2IP SSX2IP WASF1 WASF1 MAP3K7 MAP3K7 RHOA RHOA CSNK2A2 CSNK2A2 CTNNA3 CTNNA3 VCL VCL CDC42-2 CDC42-2 MAPK1 MAPK1 NECTIN2 NECTIN2 WASL WASL ACTN4 ACTN4 TJP1 TJP1 INSR INSR SMAD4 SMAD4 FGFR1 FGFR1 PTPRB PTPRB MAPK3 MAPK3 IQGAP1 IQGAP1 TCF7L1 TCF7L1 NECTIN3 NECTIN3 SRC SRC EGFR EGFR CTNND1 CTNND1 BAIAP2 BAIAP2 ACP1 ACP1 CSNK2A1 CSNK2A1 TGFBR1 TGFBR1 LEF1 LEF1 YES1 YES1 CDH1 CDH1 TCF7L2 TCF7L2 ACTN1 ACTN1 PTPRM PTPRM PARD3 PARD3 CTNNA2 CTNNA2 NECTIN4 NECTIN4 RAC2 RAC2 LMO7 LMO7 AFDN AFDN MET MET PTPRF PTPRF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CTNNA1Catenin alpha 1. (927 aa)
CTNNB1Catenin beta 1. (783 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (427 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (615 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1213 aa)
EP300E1A binding protein p300. (2425 aa)
CREBBPCREB binding protein. (2444 aa)
ACTG1Actin gamma 1. (375 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa)
WASF2WASP family member 2. (498 aa)
WASF3WASP family member 3. (502 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
FERTyrosine-protein kinase. (456 aa)
SNAI2Uncharacterized protein. (268 aa)
WASWASP actin nucleation promoting factor. (501 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
SSX2IPSSX family member 2 interacting protein. (618 aa)
WASF1WASP family member 1. (570 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
RHOARas homolog family member A. (193 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa)
CTNNA3Catenin alpha 3. (895 aa)
VCLVinculin. (1066 aa)
CDC42-2Uncharacterized protein. (191 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the PP2C family. (698 aa)
NECTIN2Nectin cell adhesion molecule 2. (539 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
ACTN4Actinin alpha 4. (933 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (2008 aa)
INSRTyrosine-protein kinase receptor. (1381 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
FGFR1Fibroblast growth factor receptor. (852 aa)
PTPRBProtein tyrosine phosphatase receptor type B. (2215 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1657 aa)
TCF7L1Transcription factor 7 like 1. (586 aa)
NECTIN3Nectin cell adhesion molecule 3. (549 aa)
SRCTyrosine-protein kinase. (678 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
CTNND1Catenin delta 1. (962 aa)
BAIAP2BAI1 associated protein 2. (548 aa)
ACP1Acid phosphatase 1. (158 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
LEF1Lymphoid enhancer binding factor 1. (415 aa)
YES1Tyrosine-protein kinase. (546 aa)
CDH1Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (881 aa)
TCF7L2Transcription factor 7 like 2. (673 aa)
ACTN1Actinin alpha 1. (927 aa)
PTPRMProtein tyrosine phosphatase receptor type M. (1511 aa)
PARD3Par-3 family cell polarity regulator. (1417 aa)
CTNNA2Catenin alpha 2. (953 aa)
NECTIN4Nectin cell adhesion molecule 4. (524 aa)
RAC2Rac family small GTPase 2. (234 aa)
LMO7LIM domain 7. (1787 aa)
AFDNAfadin, adherens junction formation factor. (1873 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1382 aa)
PTPRFProtein tyrosine phosphatase receptor type F. (2147 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.