STRINGSTRING
FCGR3A FCGR3A PRKCG PRKCG ARPC2 ARPC2 AKT3 AKT3 PRKCD PRKCD ARPC3 ARPC3 PAK1 PAK1 DNM2 DNM2 AKT1 AKT1 VAV1 VAV1 SCIN SCIN INPPL1 INPPL1 SPHK1 SPHK1 PIP5K1A PIP5K1A CRKL CRKL ASAP1 ASAP1 LOC101083342 LOC101083342 VASP VASP GAB2 GAB2 WASF2 WASF2 PLD2 PLD2 DOCK1 DOCK1 CFL2 CFL2 WASF3 WASF3 PIK3R1 PIK3R1 PRKCB PRKCB INPP5D INPP5D VAV2 VAV2 ASAP3 ASAP3 PRKCA PRKCA CFL1 CFL1 SYK SYK ARPC1A ARPC1A ARPC5 ARPC5 WAS WAS WASF1 WASF1 ARPC4 ARPC4 LOC101087936 LOC101087936 ARPC5L ARPC5L RPS6KB1 RPS6KB1 MAP2K1 MAP2K1 LYN LYN PLPP2 PLPP2 PIK3CD PIK3CD CDC42-2 CDC42-2 MAPK1 MAPK1 PLA2G4D PLA2G4D MARCKSL1 MARCKSL1 PLA2G4A PLA2G4A PIK3CB PIK3CB HCK HCK RAF1 RAF1 MAPK3 MAPK3 LIMK1 LIMK1 PRKCE PRKCE MYO10 MYO10 PLD1 PLD1 PIK3CA PIK3CA BIN1 BIN1 MARCKS MARCKS PLCG2 PLCG2 ASAP2 ASAP2 SPHK2 SPHK2 PIP5K1B PIP5K1B PIK3R2 PIK3R2 CRK CRK VAV3 VAV3 PIK3R3 PIK3R3 GSN GSN PLA2G4E PLA2G4E RPS6KB2 RPS6KB2 PLCG1 PLCG1 RAC2 RAC2 LIMK2 LIMK2 ARF6 ARF6 AKT2 AKT2 NCF1 NCF1 PLPP3 PLPP3 AMPH AMPH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FCGR3ACD16. (250 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (867 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
VAV1Vav guanine nucleotide exchange factor 1. (846 aa)
SCINScinderin. (715 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1264 aa)
SPHK1Sphingosine kinase 1. (473 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (550 aa)
CRKLCRK like proto-oncogene, adaptor protein. (342 aa)
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 1. (1138 aa)
LOC101083342Phospholipase A2. (781 aa)
VASPVasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (383 aa)
GAB2GRB2 associated binding protein 2. (678 aa)
WASF2WASP family member 2. (498 aa)
PLD2Phospholipase. (984 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1889 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
WASF3WASP family member 3. (502 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1181 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
ASAP3ArfGAP with SH3 domain, ankyrin repeat and PH domain 3. (885 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (784 aa)
CFL1ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (166 aa)
SYKSpleen associated tyrosine kinase. (636 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (397 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
WASWASP actin nucleation promoting factor. (501 aa)
WASF1WASP family member 1. (570 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (187 aa)
LOC101087936Uncharacterized protein. (373 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
LYNTyrosine-protein kinase. (526 aa)
PLPP2Phospholipid phosphatase 2. (294 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
CDC42-2Uncharacterized protein. (191 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the PP2C family. (698 aa)
PLA2G4DPhospholipase A2. (814 aa)
MARCKSL1MARCKS like 1. (198 aa)
PLA2G4APhospholipase A2. (749 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
HCKTyrosine-protein kinase. (523 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
LIMK1LIM domain kinase 1. (763 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2047 aa)
PLD1Phospholipase. (1074 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
BIN1Bridging integrator 1. (608 aa)
MARCKSMyristoylated alanine rich protein kinase C substrate. (353 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1318 aa)
ASAP2ArfGAP with SH3 domain, ankyrin repeat and PH domain 2. (1008 aa)
SPHK2DAGKc domain-containing protein. (660 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (548 aa)
PIK3R2Phosphoinositide-3-kinase regulatory subunit 2. (726 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
PIK3R3Uncharacterized protein. (461 aa)
GSNGelsolin. (815 aa)
PLA2G4EPhospholipase A2. (862 aa)
RPS6KB2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (497 aa)
PLCG1Phosphoinositide phospholipase C. (1391 aa)
RAC2Rac family small GTPase 2. (234 aa)
LIMK2LIM domain kinase 2. (711 aa)
ARF6Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (140 aa)
AKT2Non-specific serine/threonine protein kinase. (571 aa)
NCF1Neutrophil cytosolic factor 1. (390 aa)
PLPP3acidPPc domain-containing protein. (324 aa)
AMPHAmphiphysin. (856 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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