STRINGSTRING
ADCY6 ADCY6 PRKCG PRKCG RPS6KA5 RPS6KA5 ITPR1 ITPR1 MTNR1B MTNR1B ADCY3 ADCY3 ADCY4 ADCY4 RASD1 RASD1 CALML6 CALML6 ADCY8 ADCY8 CALML4 CALML4 GNAI2 GNAI2 GNAI1 GNAI1 PRKG2 PRKG2 GNG13 GNG13 PRKCB PRKCB PRKCA PRKCA CACNA1G CACNA1G GNB3 GNB3 CACNA1I CACNA1I ITPR3 ITPR3 GRIN2A GRIN2A ADCY10 ADCY10 PER1 PER1 LOC102900772 LOC102900772 CACNA1H CACNA1H GRIN2D GRIN2D CALM2 CALM2 GNB1 GNB1 GNGT1 GNGT1 ADCY9 ADCY9 PRKACA PRKACA NOS1 NOS1 GNB2 GNB2 GNG14 GNG14 RYR3 RYR3 GNAQ GNAQ MTNR1A MTNR1A KCNJ3 KCNJ3 MAPK1 MAPK1 GNB4 GNB4 GNG11 GNG11 GNGT2 GNGT2 CALML3 CALML3 GNAI3 GNAI3 ADCY7 ADCY7 CACNA1C CACNA1C LOC101097703 LOC101097703 PRKG1 PRKG1 KCNJ5 KCNJ5 KCNJ9 KCNJ9 GNG3 GNG3 MAPK3 MAPK3 GRIA1 GRIA1 GRIA2 GRIA2 PLCB2 PLCB2 GUCY1A1 GUCY1A1 GNG5 GNG5 PRKACB PRKACB PLCB1 PLCB1 GUCY1B1 GUCY1B1 PER2 PER2 ENSFCAP00000043586 ENSFCAP00000043586 CAMK2B CAMK2B GRIN2B GRIN2B FOS FOS GNG12 GNG12 GNG8 GNG8 GRIA3 GRIA3 GNG10 GNG10 CACNA1D CACNA1D GUCY1A2 GUCY1A2 GNAS GNAS RYR2 RYR2 PLCB4 PLCB4 ADCY2 ADCY2 PLCB3 PLCB3 GRIN1 GRIN1 ADCY1 ADCY1 RPS14 RPS14 GRIN2C GRIN2C GRIA4 GRIA4 KCNJ6 KCNJ6 RYR1 RYR1 LOC101090105 LOC101090105 GNG2 GNG2 ADCY5 ADCY5 GNB5 GNB5 CAMK2D CAMK2D GNG4 GNG4 GNAO1 GNAO1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1208 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
RPS6KA5Ribosomal protein S6 kinase. (798 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2757 aa)
MTNR1BMelatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family. (380 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1010 aa)
RASD1Ras related dexamethasone induced 1. (279 aa)
CALML6Calmodulin like 6. (180 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
CALML4Calmodulin like 4. (196 aa)
GNAI2G protein subunit alpha i2. (436 aa)
GNAI1G protein subunit alpha i1. (354 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
GNG13G protein subunit gamma 13. (67 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (784 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2375 aa)
GNB3G protein subunit beta 3. (339 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2184 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
ADCY10Adenylate cyclase 10. (1608 aa)
PER1Period circadian regulator 1. (1373 aa)
LOC102900772Uncharacterized protein. (247 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2240 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1338 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (149 aa)
GNB1G protein subunit beta 1. (340 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
NOS1Nitric oxide synthase 1. (1462 aa)
GNB2G protein subunit beta 2. (340 aa)
GNG14Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
RYR3Ryanodine receptor 3. (4859 aa)
GNAQG protein subunit alpha q. (359 aa)
MTNR1AMelatonin receptor 1A; Belongs to the G-protein coupled receptor 1 family. (364 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the PP2C family. (698 aa)
GNB4G protein subunit beta 4. (340 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
GNAI3G protein subunit alpha i3. (354 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2187 aa)
LOC101097703EF-hand domain-containing protein; Belongs to the calmodulin family. (86 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (392 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (906 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (618 aa)
PER2Period circadian regulator 2. (1260 aa)
ENSFCAP00000043586Uncharacterized protein. (261 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (748 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1486 aa)
FOSProto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] (381 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (894 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2216 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (791 aa)
GNASGNAS complex locus. (968 aa)
RYR2Ryanodine receptor 2. (4967 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1209 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1135 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1245 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (1008 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1148 aa)
RPS14Calcium/calmodulin dependent protein kinase II alpha. (566 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1325 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (901 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (451 aa)
RYR1Ryanodine receptor 1. (5041 aa)
LOC101090105Uncharacterized protein. (1608 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (152 aa)
ADCY5Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1329 aa)
GNB5G protein subunit beta 5. (403 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (544 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (250 aa)
GNAO1G protein subunit alpha o1. (370 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.