82 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAD2L2	Mitotic arrest deficient 2 like 2. (211 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1208 aa)
	STK10	Serine/threonine kinase 10. (967 aa)
	LOC101099765	Uncharacterized protein. (226 aa)
	MAPK10	Mitogen-activated protein kinase. (467 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
	MOS	MOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (348 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	CCNA1	Cyclin A1; Belongs to the cyclin family. (421 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	MAD1L1	Mitotic arrest deficient 1 like 1. (916 aa)
	CDC26	Cell division cycle 26. (85 aa)
	ADCY4	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1010 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
	GNAI2	G protein subunit alpha i2. (436 aa)
	GNAI1	G protein subunit alpha i1. (354 aa)
	CDC25A	Cell division cycle 25A. (524 aa)
	RPS6KA6	Ribosomal protein S6 kinase. (744 aa)
	CCNB2	Cyclin B2; Belongs to the cyclin family. (397 aa)
	SLC29A1	Heat shock protein 90 alpha family class B member 1. (740 aa)
	ANAPC2	Anaphase promoting complex subunit 2; Belongs to the cullin family. (1031 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
	MAPK11	Mitogen-activated protein kinase. (364 aa)
	ANAPC5	Anaphase promoting complex subunit 5. (755 aa)
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (804 aa)
	PLK1	Serine/threonine-protein kinase PLK. (604 aa)
	KIF22	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (664 aa)
	CDC16	Cell division cycle 16. (620 aa)
	BUB1	BUB1 mitotic checkpoint serine/threonine kinase. (1086 aa)
	CDK1	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
	KRAS	Uncharacterized protein. (380 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1367 aa)
	SPDYC	Speedy/RINGO cell cycle regulator family member C. (243 aa)
	AURKA	Aurora kinase A; Belongs to the protein kinase superfamily. (404 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
	PDE3B	Phosphodiesterase. (1122 aa)
	CCNA2	Cyclin A2; Belongs to the cyclin family. (432 aa)
	ANAPC7	Anaphase promoting complex subunit 7. (598 aa)
	SPDYA	Speedy/RINGO cell cycle regulator family member A. (309 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
	CPEB2	Cytoplasmic polyadenylation element binding protein 2. (1045 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	ANAPC1	Anaphase promoting complex subunit 1. (1943 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the PP2C family. (698 aa)
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
	GNAI3	G protein subunit alpha i3. (354 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
	CPEB3	Cytoplasmic polyadenylation element binding protein 3. (764 aa)
	CPEB1	Uncharacterized protein. (706 aa)
	RPS6KA3	Ribosomal protein S6 kinase. (740 aa)
	MAPK12	Mitogen-activated protein kinase. (367 aa)
	MAD2L1	Mitotic arrest deficient 2 like 1. (221 aa)
	RAF1	Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
	RPS6KA1	Ribosomal protein S6 kinase. (744 aa)
	CPEB4	Cytoplasmic polyadenylation element binding protein 4. (729 aa)
	CCNB3	Uncharacterized protein; Belongs to the cyclin family. (285 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	CCNB1	Cyclin B1; Belongs to the cyclin family. (600 aa)
	MAPK8	Mitogen-activated protein kinase. (427 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
	HSP90AA1	Heat shock protein 90 alpha family class A member 1. (753 aa)
	IGF1	Insulin like growth factor 1. (195 aa)
	ANAPC13	Anaphase promoting complex subunit 13. (74 aa)
	ARAF	A-Raf proto-oncogene, serine/threonine kinase. (659 aa)
	RPS6KA2	Ribosomal protein S6 kinase. (741 aa)
	ANAPC4	Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (812 aa)
	PIK3R2	Phosphoinositide-3-kinase regulatory subunit 2. (726 aa)
	ANAPC10	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (252 aa)
	PIK3R3	Uncharacterized protein. (461 aa)
	MAPK9	Mitogen-activated protein kinase. (424 aa)
	PGR	Progesterone receptor. (932 aa)
	FZR1	Fizzy and cell division cycle 20 related 1. (493 aa)
	CDC27	Cell division cycle 27. (839 aa)
	ADCY2	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1135 aa)
	PKMYT1	Protein kinase, membrane associated tyrosine/threonine 1. (574 aa)
	LOC102901812	Uncharacterized protein. (283 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1148 aa)
	ADCY5	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1329 aa)
	AKT2	Non-specific serine/threonine protein kinase. (571 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSFCAP00000055708	ENSFCAP00000055405	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.617
ADCY1	ADCY3	ENSFCAP00000055708	ENSFCAP00000003366	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.944
ADCY1	ADCY4	ENSFCAP00000055708	ENSFCAP00000005199	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.558
ADCY1	ADCY5	ENSFCAP00000055708	ENSFCAP00000059483	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.538
ADCY1	ADCY6	ENSFCAP00000055708	ENSFCAP00000000072	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.540
ADCY1	ADCY7	ENSFCAP00000055708	ENSFCAP00000028204	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.658
ADCY1	ADCY8	ENSFCAP00000055708	ENSFCAP00000005982	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.958
ADCY1	ADCY9	ENSFCAP00000055708	ENSFCAP00000018672	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.644
ADCY1	AKT1	ENSFCAP00000055708	ENSFCAP00000004586	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.691
ADCY1	AKT2	ENSFCAP00000055708	ENSFCAP00000059662	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Non-specific serine/threonine protein kinase.	0.691
ADCY1	AKT3	ENSFCAP00000055708	ENSFCAP00000003410	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.691
ADCY1	ANAPC5	ENSFCAP00000055708	ENSFCAP00000011552	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Anaphase promoting complex subunit 5.	0.506
ADCY1	ANAPC7	ENSFCAP00000055708	ENSFCAP00000020067	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Anaphase promoting complex subunit 7.	0.507
ADCY1	GNAI1	ENSFCAP00000055708	ENSFCAP00000006650	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i1.	0.808
ADCY1	GNAI2	ENSFCAP00000055708	ENSFCAP00000006501	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i2.	0.808
ADCY1	GNAI3	ENSFCAP00000055708	ENSFCAP00000027969	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i3.	0.808
ADCY1	PDE3B	ENSFCAP00000055708	ENSFCAP00000019173	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.756
ADCY1	PRKACA	ENSFCAP00000055708	ENSFCAP00000018754	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.926
ADCY1	PRKACB	ENSFCAP00000055708	ENSFCAP00000040413	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.928
ADCY2	ADCY1	ENSFCAP00000055405	ENSFCAP00000055708	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.617