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SOCS5 | Suppressor of cytokine signaling 5. (536 aa) | ||||
CYP17A1 | Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...] (508 aa) | ||||
STAT5B | Signal transducer and activator of transcription. (786 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (770 aa) | ||||
MAPK10 | Mitogen-activated protein kinase. (467 aa) | ||||
HRAS | HRas proto-oncogene, GTPase. (189 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
SHC3 | SHC adaptor protein 3. (587 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (321 aa) | ||||
NFKB1 | Nuclear factor kappa B subunit 1. (989 aa) | ||||
SOCS6 | Suppressor of cytokine signaling 6. (497 aa) | ||||
LHCGR | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (700 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (725 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (364 aa) | ||||
IRF1 | Interferon regulatory factor. (322 aa) | ||||
MAP2K2 | Protein kinase domain-containing protein. (549 aa) | ||||
GCK | Phosphotransferase. (466 aa) | ||||
PRL | Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation. (229 aa) | ||||
SHC2 | SHC adaptor protein 2. (583 aa) | ||||
KRAS | Uncharacterized protein. (380 aa) | ||||
SOCS3 | Suppressor of cytokine signaling 3. (225 aa) | ||||
ESR1 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] (595 aa) | ||||
MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) | ||||
SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa) | ||||
FOXO3 | Forkhead box O3. (672 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) | ||||
GRB2 | Growth factor receptor bound protein 2. (217 aa) | ||||
MAPK14 | Mitogen-activated protein kinase. (360 aa) | ||||
LHB | Lutropin subunit beta; Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. (143 aa) | ||||
SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) | ||||
MAPK1 | Mitogen-activated protein kinase; Belongs to the PP2C family. (698 aa) | ||||
CGA | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. (152 aa) | ||||
PRLR | Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (624 aa) | ||||
PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) | ||||
ELF5 | E74 like ETS transcription factor 5. (275 aa) | ||||
SHC4 | SHC adaptor protein 4. (630 aa) | ||||
SOCS4 | Suppressor of cytokine signaling 4. (441 aa) | ||||
MAPK12 | Mitogen-activated protein kinase. (367 aa) | ||||
RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) | ||||
NRAS | NRAS proto-oncogene, GTPase. (189 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) | ||||
SOCS7 | Suppressor of cytokine signaling 7. (640 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
MAPK8 | Mitogen-activated protein kinase. (427 aa) | ||||
CRADD | Uncharacterized protein. (398 aa) | ||||
TH | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (557 aa) | ||||
SRC | Tyrosine-protein kinase. (678 aa) | ||||
CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) | ||||
ESR2 | Estrogen receptor 2. (574 aa) | ||||
PIK3R2 | Phosphoinositide-3-kinase regulatory subunit 2. (726 aa) | ||||
GSK3B | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (433 aa) | ||||
FOS | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] (381 aa) | ||||
PIK3R3 | Uncharacterized protein. (461 aa) | ||||
MAPK9 | Mitogen-activated protein kinase. (424 aa) | ||||
SOCS1 | Suppressor of cytokine signaling 1. (203 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (555 aa) | ||||
JAK2 | Tyrosine-protein kinase. (1131 aa) | ||||
CISH | Cytokine inducible SH2 containing protein. (257 aa) | ||||
STAT1 | Signal transducer and activator of transcription. (885 aa) | ||||
CCND1 | Cyclin D1; Belongs to the cyclin family. (312 aa) | ||||
STAT5A | Signal transducer and activator of transcription. (794 aa) | ||||
SLC2A2 | Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (571 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase. (571 aa) | ||||
TNFRSF11A | TNF receptor superfamily member 11a. (638 aa) | ||||
LOC101100876 | Uncharacterized protein. (127 aa) | ||||
GALT | Galactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. (460 aa) |