STRINGSTRING
PRKCG PRKCG PDPK1 PDPK1 SCNN1G SCNN1G SCNN1B SCNN1B ATP1B1 ATP1B1 PIK3R1 PIK3R1 PRKCB PRKCB PRKCA PRKCA ATP1A3 ATP1A3 KRAS KRAS SLC9A3R2 SLC9A3R2 NR3C2 NR3C2 IRS1 IRS1 ATP1B3 ATP1B3 PIK3CD PIK3CD MAPK1 MAPK1 PIK3CB PIK3CB INSR INSR ATP1A1 ATP1A1 MAPK3 MAPK3 HSD11B2 HSD11B2 SCNN1A SCNN1A PIK3CA PIK3CA KCNJ1 KCNJ1 IGF1 IGF1 PIK3R2 PIK3R2 ATP1B4 ATP1B4 PIK3R3 PIK3R3 FXYD4 FXYD4 SGK1 SGK1 NEDD4L NEDD4L ATP1A4 ATP1A4 FXYD2 FXYD2 SFN SFN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (558 aa)
SCNN1GSodium channel epithelial 1 gamma subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (646 aa)
SCNN1BSodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (763 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (784 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
KRASUncharacterized protein. (380 aa)
SLC9A3R2Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (337 aa)
NR3C2Nuclear receptor subfamily 3 group C member 2. (987 aa)
IRS1Insulin receptor substrate 1. (1234 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the PP2C family. (698 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
INSRTyrosine-protein kinase receptor. (1381 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1038 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
HSD11B2Hydroxysteroid 11-beta dehydrogenase 2. (405 aa)
SCNN1AUncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (645 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
KCNJ1Potassium voltage-gated channel subfamily J member 1. (391 aa)
IGF1Insulin like growth factor 1. (195 aa)
PIK3R2Phosphoinositide-3-kinase regulatory subunit 2. (726 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (357 aa)
PIK3R3Uncharacterized protein. (461 aa)
FXYD4FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (89 aa)
SGK1Non-specific serine/threonine protein kinase. (584 aa)
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (1246 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1074 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
SFNStratifin; Belongs to the 14-3-3 family. (252 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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