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G6PC3 G6PC3 HK3 HK3 AKT3 AKT3 HKDC1 HKDC1 HK1 HK1 AKT1 AKT1 HK2 HK2 G6PC2 G6PC2 TAS1R3 TAS1R3 ATP1B1 ATP1B1 LCT LCT PIK3R1 PIK3R1 PRKCB PRKCB ATP1A3 ATP1A3 MGAM MGAM ATP1B3 ATP1B3 SI SI PIK3CD PIK3CD G6PC G6PC SLC37A4 SLC37A4 GNAT3 GNAT3 PIK3CB PIK3CB SLC2A5 SLC2A5 ATP1A1 ATP1A1 PLCB2 PLCB2 PIK3CA PIK3CA AMY2B AMY2B PLCB1 PLCB1 PIK3R2 PIK3R2 ATP1B4 ATP1B4 PIK3R3 PIK3R3 CACNA1D CACNA1D PLCB4 PLCB4 PLCB3 PLCB3 SLC2A2 SLC2A2 ATP1A4 ATP1A4 AKT2 AKT2 FXYD2 FXYD2 ENSFCAP00000060733 ENSFCAP00000060733 SLC5A1 SLC5A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
HK3Hexokinase 3. (924 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
HKDC1Hexokinase domain containing 1. (917 aa)
HK1Hexokinase 1. (1056 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
HK2Hexokinase 2. (917 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
TAS1R3Taste receptor type 1 member 3; Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate) (By similarity). (865 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
LCTLactase. (1929 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
MGAMMaltase-glucoamylase. (2656 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
SISucrase-isomaltase. (1804 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
G6PCGlucose-6-phosphatase; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels (By similarity). Belongs to the glucose-6-phosphatase family. (357 aa)
SLC37A4Solute carrier family 37 member 4. (451 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
SLC2A5Solute carrier family 2 member 5; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (526 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1038 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
AMY2BAlpha-amylase. (511 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
PIK3R2Phosphoinositide-3-kinase regulatory subunit 2. (726 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (357 aa)
PIK3R3Uncharacterized protein. (461 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2216 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1209 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1245 aa)
SLC2A2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (571 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1074 aa)
AKT2Non-specific serine/threonine protein kinase. (571 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
ENSFCAP00000060733P-type domain-containing protein; Belongs to the glycosyl hydrolase 31 family. (482 aa)
SLC5A1Solute carrier family 5 member 1. (998 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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