STRINGSTRING
ATP5F1C ATP5F1C BAX BAX PSMD6 PSMD6 TUBAL3 TUBAL3 PSMC2 PSMC2 PINK1 PINK1 PSMD8 PSMD8 PSMC4 PSMC4 TXN2 TXN2 NDUFA2 NDUFA2 UBA1 UBA1 COX5B COX5B NDUFV1 NDUFV1 LRRK2 LRRK2 PSMB4 PSMB4 DDIT3 DDIT3 UQCRC1 UQCRC1 MAPK10 MAPK10 ITPR1 ITPR1 LOC101086703 LOC101086703 PSMD13 PSMD13 NDUFS8 NDUFS8 PSMC5 PSMC5 ERN1 ERN1 NDUFA3 NDUFA3 TUBB4B TUBB4B LOC101090556 LOC101090556 DAXX DAXX KLC2 KLC2 ITPR2 ITPR2 CALML6 CALML6 TUBB1 TUBB1 CALML4 CALML4 GNAI2 GNAI2 SLC25A5 SLC25A5 SLC25A31 SLC25A31 HTRA2 HTRA2 GNAI1 GNAI1 UQCRC2 UQCRC2 PSMD2 PSMD2 MAP3K5 MAP3K5 ATF4 ATF4 KLC4 KLC4 UBA52 UBA52 UBA7 UBA7 LOC101099268 LOC101099268 PSMA1 PSMA1 CYC1 CYC1 SLC18A1 SLC18A1 NDUFB10 NDUFB10 HSPA5 HSPA5 TUBA1C TUBA1C ATP5F1B ATP5F1B NFE2L2 NFE2L2 EIF2AK3 EIF2AK3 ATP5MC3 ATP5MC3 SLC18A2 SLC18A2 MAOB MAOB NDUFAB1 NDUFAB1 NDUFB7 NDUFB7 ITPR3 ITPR3 COX7A1 COX7A1 NDUFA13 NDUFA13 PSMB7 PSMB7 COX8A COX8A COX4I2 COX4I2 NDUFA7 NDUFA7 LOC102900772 LOC102900772 NDUFA11 NDUFA11 CALM2 CALM2 PSMD9 PSMD9 NDUFA6 NDUFA6 NDUFA12 NDUFA12 ATP5PO ATP5PO PSMD7 PSMD7 KIF5B KIF5B ATP5PB ATP5PB CASP9 CASP9 PSMA6 PSMA6 RPS27A RPS27A NDUFS1 NDUFS1 PRKACA PRKACA NDUFB11 NDUFB11 PARK7 PARK7 EIF2S1 EIF2S1 ATP5F1A ATP5F1A UQCRQ UQCRQ NDUFS7 NDUFS7 VDAC2 VDAC2 PSMD12 PSMD12 NDUFB3 NDUFB3 UQCRFS1 UQCRFS1 ADORA2A ADORA2A RYR3 RYR3 LOC101100947 LOC101100947 TUBB TUBB NDUFS5 NDUFS5 PSMD11 PSMD11 PSMA2 PSMA2 SDHD SDHD LOC101080736 LOC101080736 UBE2L6 UBE2L6 M3XDY9_FELCA M3XDY9_FELCA UBE2J1 UBE2J1 PSMA8 PSMA8 PPIF PPIF ND2 ND2 COX1 COX1 COX2 COX2 ATP8 ATP8 ATP6 ATP6 COX3 COX3 ND3 ND3 ND4L ND4L ND4 ND4 ND5 ND5 ND6 ND6 CYTB CYTB ND1 ND1 PSMB6 PSMB6 MFN2 MFN2 SNCA SNCA CALML3 CALML3 GNAI3 GNAI3 UCHL1 UCHL1 KIF5C KIF5C SDHC SDHC LOC101097703 LOC101097703 SEPTIN5 SEPTIN5 NDUFS6 NDUFS6 NDUFS2 NDUFS2 LOC102899183 LOC102899183 TUBB6 TUBB6 LOC101100266 LOC101100266 UBC UBC MFN1 MFN1 NDUFB2 NDUFB2 CASP3 CASP3 LOC101096876 LOC101096876 COX7B COX7B KIF5A KIF5A NDUFB1 NDUFB1 KLC1 KLC1 PSMA5 PSMA5 ENSFCAP00000034800 ENSFCAP00000034800 NDUFB5 NDUFB5 SLC25A4 SLC25A4 NDUFA1 NDUFA1 GPR37 GPR37 NDUFA5 NDUFA5 PSMC1 PSMC1 COX7B2 COX7B2 VDAC1 VDAC1 TUBA4A TUBA4A NDUFA4 NDUFA4 ENSFCAP00000038072 ENSFCAP00000038072 SNCAIP SNCAIP MAPK8 MAPK8 SEM1 SEM1 TH TH PRKACB PRKACB TXN TXN SDHA SDHA GNAL GNAL XBP1 XBP1 ATP5PF ATP5PF NDUFB8 NDUFB8 PRKN PRKN PSMC3 PSMC3 LOC105261211 LOC105261211 LOC101095773 LOC101095773 ENSFCAP00000043586 ENSFCAP00000043586 TUBA8 TUBA8 PSMD14 PSMD14 CAMK2B CAMK2B UBE2L3 UBE2L3 NDUFB9 NDUFB9 SUMO3 SUMO3 APAF1 APAF1 MAOA MAOA MAPK9 MAPK9 ENSFCAP00000047742 ENSFCAP00000047742 PSMA4 PSMA4 SLC25A6 SLC25A6 PSMD4 PSMD4 PSMB5 PSMB5 NDUFS3 NDUFS3 ATF6 ATF6 NDUFV3 NDUFV3 DRD1 DRD1 COX4I1 COX4I1 LOC101095032 LOC101095032 PSMD1 PSMD1 UBE2J2 UBE2J2 NDUFA4L2 NDUFA4L2 MCU MCU ATP5F1D ATP5F1D PSMB1 PSMB1 NDUFA9 NDUFA9 GNAS GNAS NDUFB4 NDUFB4 PSMA3 PSMA3 DUSP1 DUSP1 NDUFS4 NDUFS4 PLCG1 PLCG1 VDAC3 VDAC3 UBE2G1 UBE2G1 RPS14 RPS14 TRAP1 TRAP1 KLC3 KLC3 PSMB2 PSMB2 ATP5MC1 ATP5MC1 PSMC6 PSMC6 PSMB3 PSMB3 BCL2L1 BCL2L1 ADCY5 ADCY5 SDHB SDHB NDUFA8 NDUFA8 UQCRB UQCRB CAMK2D CAMK2D NDUFV2 NDUFV2 PSMD3 PSMD3 LOC101081808 LOC101081808 UQCR10 UQCR10 NDUFA10 NDUFA10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP5F1CATP synthase subunit gamma. (298 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (478 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
PINK1PTEN induced kinase 1. (581 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (355 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
TXN2Thioredoxin 2. (163 aa)
NDUFA2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (99 aa)
UBA1Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. (1058 aa)
COX5BCytochrome c oxidase subunit 5B. (129 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
DDIT3DNA damage inducible transcript 3. (167 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (481 aa)
MAPK10Mitogen-activated protein kinase. (467 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2757 aa)
LOC101086703Uncharacterized protein. (56 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
NDUFS8NADH:ubiquinone oxidoreductase core subunit S8. (210 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (972 aa)
NDUFA3Uncharacterized protein. (84 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
LOC101090556Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
DAXXDeath domain associated protein. (748 aa)
KLC2Kinesin light chain 2. (622 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
CALML6Calmodulin like 6. (180 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (457 aa)
CALML4Calmodulin like 4. (196 aa)
GNAI2G protein subunit alpha i2. (436 aa)
SLC25A5Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
SLC25A31Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa)
HTRA2HtrA serine peptidase 2. (458 aa)
GNAI1G protein subunit alpha i1. (354 aa)
UQCRC2Ubiquinol-cytochrome c reductase core protein 2; Belongs to the peptidase M16 family. (453 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1366 aa)
ATF4Activating transcription factor 4. (352 aa)
KLC4Kinesin light chain 4. (615 aa)
UBA52Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (128 aa)
UBA7Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family. (1012 aa)
LOC101099268Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (515 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
CYC1Cytochrome c1. (325 aa)
SLC18A1Solute carrier family 18 member A1. (519 aa)
NDUFB10NADH:ubiquinone oxidoreductase subunit B10. (170 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
TUBA1CTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (518 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (606 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1114 aa)
ATP5MC3ATP synthase membrane subunit c locus 3; Belongs to the ATPase C chain family. (178 aa)
SLC18A2Solute carrier family 18 member A2. (517 aa)
MAOBAmine oxidase. (520 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (154 aa)
NDUFB7NADH:ubiquinone oxidoreductase subunit B7. (137 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
COX7A1Cytochrome c oxidase subunit 7A1. (80 aa)
NDUFA13NADH:ubiquinone oxidoreductase subunit A13. (144 aa)
PSMB7Proteasome subunit beta. (277 aa)
COX8ACytochrome c oxidase subunit 8A. (69 aa)
COX4I2Cytochrome c oxidase subunit 4I2. (182 aa)
NDUFA7Uncharacterized protein. (113 aa)
LOC102900772Uncharacterized protein. (247 aa)
NDUFA11Uncharacterized protein. (141 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (149 aa)
PSMD9Proteasome 26S subunit, non-ATPase 9. (284 aa)
NDUFA6NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (128 aa)
NDUFA12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa)
ATP5POUncharacterized protein. (213 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
ATP5PBATP synthase peripheral stalk-membrane subunit b. (251 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (451 aa)
PSMA6Proteasome subunit alpha type. (251 aa)
RPS27ARibosomal protein S27a. (156 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1. (691 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
NDUFB11NADH:ubiquinone oxidoreductase subunit B11. (241 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
NDUFS7NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family. (306 aa)
VDAC2Voltage dependent anion channel 2. (294 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
NDUFB3NADH:ubiquinone oxidoreductase subunit B3. (98 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
RYR3Ryanodine receptor 3. (4859 aa)
LOC101100947Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
TUBBTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
NDUFS5NADH:ubiquinone oxidoreductase subunit S5. (178 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa)
LOC101080736NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (120 aa)
UBE2L6Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
M3XDY9_FELCAUncharacterized protein. (92 aa)
UBE2J1Ubiquitin conjugating enzyme E2 J1. (318 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (204 aa)
ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (347 aa)
COX1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (514 aa)
COX2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (227 aa)
ATP8ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (67 aa)
ATP6ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (226 aa)
COX3Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (261 aa)
ND3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (115 aa)
ND4LNADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (98 aa)
ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (459 aa)
ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (606 aa)
ND6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (175 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa)
ND1NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (318 aa)
PSMB6Proteasome subunit beta. (239 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (140 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
GNAI3G protein subunit alpha i3. (354 aa)
UCHL1Ubiquitin carboxyl-terminal hydrolase. (347 aa)
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (957 aa)
SDHCSuccinate dehydrogenase complex subunit C. (184 aa)
LOC101097703EF-hand domain-containing protein; Belongs to the calmodulin family. (86 aa)
SEPTIN5Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (463 aa)
NDUFS6NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (125 aa)
NDUFS2NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (489 aa)
LOC102899183Uncharacterized protein. (63 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
LOC101100266Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (86 aa)
UBCUncharacterized protein. (304 aa)
MFN1Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (804 aa)
NDUFB2NADH:ubiquinone oxidoreductase subunit B2. (105 aa)
CASP3Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (302 aa)
LOC101096876COX6C domain-containing protein. (75 aa)
COX7BCytochrome c oxidase subunit 7B. (80 aa)
KIF5AKinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1039 aa)
NDUFB1Uncharacterized protein. (104 aa)
KLC1Uncharacterized protein. (628 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
ENSFCAP00000034800Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (93 aa)
NDUFB5NADH:ubiquinone oxidoreductase subunit B5. (242 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
NDUFA1Uncharacterized protein. (70 aa)
GPR37G protein-coupled receptor 37. (613 aa)
NDUFA5NADH:ubiquinone oxidoreductase subunit A5. (117 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
COX7B2Cytochrome c oxidase subunit 7B2. (79 aa)
VDAC1Voltage dependent anion channel 1. (283 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
NDUFA4Uncharacterized protein. (82 aa)
ENSFCAP00000038072Uncharacterized protein. (92 aa)
SNCAIPSynuclein alpha interacting protein. (1014 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
SEM1Uncharacterized protein. (70 aa)
THInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (557 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
GNALG protein subunit alpha L. (455 aa)
XBP1X-box binding protein 1. (383 aa)
ATP5PFATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (116 aa)
NDUFB8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (462 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (439 aa)
LOC105261211Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (88 aa)
LOC101095773Cytochrome c oxidase subunit 6A, mitochondrial. (109 aa)
ENSFCAP00000043586Uncharacterized protein. (261 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (481 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (748 aa)
UBE2L3UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (247 aa)
NDUFB9NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (179 aa)
SUMO3Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (289 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1250 aa)
MAOAAmine oxidase. (1178 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
ENSFCAP00000047742Uncharacterized protein. (97 aa)
PSMA4Proteasome subunit alpha type. (277 aa)
SLC25A6Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (318 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (423 aa)
PSMB5Proteasome subunit beta. (263 aa)
NDUFS3NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (265 aa)
ATF6Activating transcription factor 6. (669 aa)
NDUFV3Uncharacterized protein. (107 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (463 aa)
COX4I1Cytochrome c oxidase subunit 4I1. (201 aa)
LOC101095032Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (91 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
UBE2J2UBIQUITIN_CONJUGAT_2 domain-containing protein. (259 aa)
NDUFA4L2NDUFA4 mitochondrial complex associated like 2. (91 aa)
MCUMitochondrial calcium uniporter. (475 aa)
ATP5F1DATP-synt_DE_N domain-containing protein. (282 aa)
PSMB1Proteasome subunit beta. (261 aa)
NDUFA9NADH:ubiquinone oxidoreductase subunit A9. (389 aa)
GNASGNAS complex locus. (968 aa)
NDUFB4NADH:ubiquinone oxidoreductase subunit B4. (132 aa)
PSMA3Proteasome subunit alpha type. (258 aa)
DUSP1Dual specificity phosphatase 1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (434 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (187 aa)
PLCG1Phosphoinositide phospholipase C. (1391 aa)
VDAC3Voltage dependent anion channel 3. (315 aa)
UBE2G1Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (334 aa)
RPS14Calcium/calmodulin dependent protein kinase II alpha. (566 aa)
TRAP1TNF receptor associated protein 1. (710 aa)
KLC3Kinesin light chain 3. (637 aa)
PSMB2Proteasome subunit beta. (201 aa)
ATP5MC1ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (142 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (477 aa)
PSMB3Proteasome subunit beta. (268 aa)
BCL2L1BCL2 like 1. (271 aa)
ADCY5Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1329 aa)
SDHBSuccinate dehydrogenase complex iron sulfur subunit B. (307 aa)
NDUFA8NADH:ubiquinone oxidoreductase subunit A8. (331 aa)
UQCRBUbiquinol-cytochrome c reductase binding protein. (137 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (544 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (256 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (595 aa)
LOC101081808Uncharacterized protein. (154 aa)
UQCR10Ubiquinol-cytochrome c reductase, complex III subunit X. (182 aa)
NDUFA10NADH:ubiquinone oxidoreductase subunit A10. (442 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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