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MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2590 aa) | ||||
ATP5F1C | ATP synthase subunit gamma. (298 aa) | ||||
BAX | BCL2 associated X, apoptosis regulator. (192 aa) | ||||
TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa) | ||||
PSMD6 | Proteasome 26S subunit, non-ATPase 6. (478 aa) | ||||
TUBAL3 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa) | ||||
PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa) | ||||
DNAH6 | Dynein axonemal heavy chain 6. (4155 aa) | ||||
PSMD8 | Proteasome 26S subunit, non-ATPase 8. (355 aa) | ||||
PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) | ||||
ACTR1A | Actin related protein 1A. (376 aa) | ||||
NDUFA2 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (99 aa) | ||||
COX5B | Cytochrome c oxidase subunit 5B. (129 aa) | ||||
NDUFV1 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa) | ||||
PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) | ||||
POLR2K | Uncharacterized protein. (58 aa) | ||||
UQCRC1 | Ubiquinol-cytochrome c reductase core protein 1. (481 aa) | ||||
MAPK10 | Mitogen-activated protein kinase. (467 aa) | ||||
ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2757 aa) | ||||
LOC101086703 | Uncharacterized protein. (56 aa) | ||||
PSMD13 | Proteasome 26S subunit, non-ATPase 13. (376 aa) | ||||
NDUFS8 | NADH:ubiquinone oxidoreductase core subunit S8. (210 aa) | ||||
DNAI1 | Dynein axonemal intermediate chain 1. (719 aa) | ||||
PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) | ||||
ERN1 | Endoplasmic reticulum to nucleus signaling 1. (972 aa) | ||||
NDUFA3 | Uncharacterized protein. (84 aa) | ||||
TUBB4B | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa) | ||||
LOC101090556 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa) | ||||
KLC2 | Kinesin light chain 2. (622 aa) | ||||
AP2A1 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (978 aa) | ||||
HTT | Huntingtin. (3140 aa) | ||||
EP300 | E1A binding protein p300. (2425 aa) | ||||
ULK2 | Unc-51 like autophagy activating kinase 2. (1039 aa) | ||||
SLC1A3 | Amino acid transporter. (542 aa) | ||||
CREBBP | CREB binding protein. (2444 aa) | ||||
TUBB1 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (457 aa) | ||||
ATG2B | Autophagy related 2B. (2114 aa) | ||||
TBP | TATA-box binding protein. (327 aa) | ||||
SLC25A5 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) | ||||
SLC25A31 | Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa) | ||||
POLR2E | RNA polymerase II subunit E. (210 aa) | ||||
UQCRC2 | Ubiquinol-cytochrome c reductase core protein 2; Belongs to the peptidase M16 family. (453 aa) | ||||
PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) | ||||
POLR2H | DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa) | ||||
MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1366 aa) | ||||
DNALI1 | Dynein axonemal light intermediate chain 1. (278 aa) | ||||
UCP1 | Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa) | ||||
DNAH2 | Dynein axonemal heavy chain 2. (4358 aa) | ||||
KLC4 | Kinesin light chain 4. (615 aa) | ||||
RB1CC1 | RB1 inducible coiled-coil 1. (1593 aa) | ||||
RCOR1 | REST corepressor 1. (486 aa) | ||||
LOC101099268 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (515 aa) | ||||
ULK1 | Unc-51 like autophagy activating kinase 1. (1113 aa) | ||||
DNAH10 | Dynein axonemal heavy chain 10. (4501 aa) | ||||
SIN3A | SIN3 transcription regulator family member A. (1274 aa) | ||||
PSMA1 | Proteasome subunit alpha type. (263 aa) | ||||
CYC1 | Cytochrome c1. (325 aa) | ||||
TAF4B | TATA-box binding protein associated factor 4b. (869 aa) | ||||
NDUFB10 | NADH:ubiquinone oxidoreductase subunit B10. (170 aa) | ||||
TUBA1C | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (518 aa) | ||||
DNAH9 | Uncharacterized protein. (798 aa) | ||||
ATP5F1B | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa) | ||||
MAP3K10 | Mitogen-activated protein kinase kinase kinase. (937 aa) | ||||
ATG2A | Autophagy related 2A. (1928 aa) | ||||
ATP5MC3 | ATP synthase membrane subunit c locus 3; Belongs to the ATPase C chain family. (178 aa) | ||||
BECN1 | Beclin 1. (448 aa) | ||||
NDUFAB1 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (154 aa) | ||||
NDUFB7 | NADH:ubiquinone oxidoreductase subunit B7. (137 aa) | ||||
AMBRA1 | Autophagy and beclin 1 regulator 1. (1301 aa) | ||||
ATG13 | Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa) | ||||
CREB3L3 | cAMP responsive element binding protein 3 like 3. (448 aa) | ||||
COX7A1 | Cytochrome c oxidase subunit 7A1. (80 aa) | ||||
NDUFA13 | NADH:ubiquinone oxidoreductase subunit A13. (144 aa) | ||||
PSMB7 | Proteasome subunit beta. (277 aa) | ||||
COX8A | Cytochrome c oxidase subunit 8A. (69 aa) | ||||
COX4I2 | Cytochrome c oxidase subunit 4I2. (182 aa) | ||||
NDUFA7 | Uncharacterized protein. (113 aa) | ||||
DNAH5 | Dynein axonemal heavy chain 5. (4623 aa) | ||||
DNAH1 | Dynein axonemal heavy chain 1. (4266 aa) | ||||
NDUFA11 | Uncharacterized protein. (141 aa) | ||||
CREB3L1 | cAMP responsive element binding protein 3 like 1. (520 aa) | ||||
SP1 | Sp1 transcription factor. (786 aa) | ||||
PSMD9 | Proteasome 26S subunit, non-ATPase 9. (284 aa) | ||||
NDUFA6 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (128 aa) | ||||
NDUFA12 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa) | ||||
GPX5 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (222 aa) | ||||
ATG14 | Autophagy related 14. (510 aa) | ||||
ATP5PO | Uncharacterized protein. (213 aa) | ||||
IFT57 | Intraflagellar transport 57. (429 aa) | ||||
PSMD7 | Proteasome 26S subunit, non-ATPase 7. (324 aa) | ||||
KIF5B | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa) | ||||
ATP5PB | ATP synthase peripheral stalk-membrane subunit b. (251 aa) | ||||
POLR2D | RNA polymerase II subunit D. (142 aa) | ||||
CASP9 | Caspase 9; Belongs to the peptidase C14A family. (451 aa) | ||||
PSMA6 | Proteasome subunit alpha type. (251 aa) | ||||
NDUFS1 | NADH:ubiquinone oxidoreductase core subunit S1. (691 aa) | ||||
DCTN4 | Dynactin subunit 4. (550 aa) | ||||
NDUFB11 | NADH:ubiquinone oxidoreductase subunit B11. (241 aa) | ||||
CLTCL1 | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1673 aa) | ||||
ATP5F1A | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa) | ||||
UQCRQ | Ubiquinol-cytochrome c reductase complex III subunit VII. (82 aa) | ||||
NDUFS7 | NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family. (306 aa) | ||||
VDAC2 | Voltage dependent anion channel 2. (294 aa) | ||||
PSMD12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) | ||||
NDUFB3 | NADH:ubiquinone oxidoreductase subunit B3. (98 aa) | ||||
GPX8 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa) | ||||
UQCRFS1 | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa) | ||||
CLTC | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa) | ||||
DNAH14 | Uncharacterized protein. (4490 aa) | ||||
POLR2G | RNA polymerase II subunit G. (172 aa) | ||||
LOC101100947 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
TUBB | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa) | ||||
NDUFS5 | NADH:ubiquinone oxidoreductase subunit S5. (178 aa) | ||||
POLR2I | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa) | ||||
PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) | ||||
PSMA2 | Proteasome subunit alpha type. (234 aa) | ||||
SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa) | ||||
LOC101080736 | NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (120 aa) | ||||
DNAL1 | Dynein axonemal light chain 1. (190 aa) | ||||
GNAQ | G protein subunit alpha q. (359 aa) | ||||
M3XDY9_FELCA | Uncharacterized protein. (92 aa) | ||||
PSMA8 | Proteasome subunit alpha type. (250 aa) | ||||
PPIF | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (204 aa) | ||||
PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa) | ||||
ND2 | NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (347 aa) | ||||
COX1 | Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (514 aa) | ||||
COX2 | Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (227 aa) | ||||
ATP8 | ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (67 aa) | ||||
ATP6 | ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (226 aa) | ||||
COX3 | Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (261 aa) | ||||
ND3 | NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (115 aa) | ||||
ND4L | NADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (98 aa) | ||||
ND4 | NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (459 aa) | ||||
ND5 | NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (606 aa) | ||||
ND6 | NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (175 aa) | ||||
CYTB | Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa) | ||||
ND1 | NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (318 aa) | ||||
PSMB6 | Proteasome subunit beta. (239 aa) | ||||
SOD2 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa) | ||||
POLR2J | RNA polymerase II subunit J. (117 aa) | ||||
AP2A2 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (976 aa) | ||||
KIF5C | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (957 aa) | ||||
SDHC | Succinate dehydrogenase complex subunit C. (184 aa) | ||||
NDUFS6 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (125 aa) | ||||
TFAM | Transcription factor A, mitochondrial. (246 aa) | ||||
NDUFS2 | NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (489 aa) | ||||
LOC102899183 | Uncharacterized protein. (63 aa) | ||||
TUBB6 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa) | ||||
LOC101100266 | Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (86 aa) | ||||
NDUFB2 | NADH:ubiquinone oxidoreductase subunit B2. (105 aa) | ||||
CASP3 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (302 aa) | ||||
LOC101096876 | COX6C domain-containing protein. (75 aa) | ||||
GPX1 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (205 aa) | ||||
COX7B | Cytochrome c oxidase subunit 7B. (80 aa) | ||||
CREB5 | cAMP responsive element binding protein 5. (523 aa) | ||||
KIF5A | Kinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1039 aa) | ||||
HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (498 aa) | ||||
DCTN5 | Dynactin subunit 5. (182 aa) | ||||
NDUFB1 | Uncharacterized protein. (104 aa) | ||||
KLC1 | Uncharacterized protein. (628 aa) | ||||
PSMA5 | Proteasome subunit alpha type. (241 aa) | ||||
SOD1 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (155 aa) | ||||
ENSFCAP00000034800 | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (93 aa) | ||||
NDUFB5 | NADH:ubiquinone oxidoreductase subunit B5. (242 aa) | ||||
SLC25A4 | Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) | ||||
HDAC2 | Histone deacetylase 2. (602 aa) | ||||
GRIA1 | Glutamate ionotropic receptor AMPA type subunit 1. (906 aa) | ||||
GRIA2 | Glutamate ionotropic receptor AMPA type subunit 2. (883 aa) | ||||
TBPL1 | TATA-box binding protein like 1. (186 aa) | ||||
NDUFA1 | Uncharacterized protein. (70 aa) | ||||
NDUFA5 | NADH:ubiquinone oxidoreductase subunit A5. (117 aa) | ||||
PSMC1 | AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa) | ||||
PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa) | ||||
ATG101 | Autophagy related 101. (344 aa) | ||||
DLG4 | Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (797 aa) | ||||
POLR2C | RNA polymerase II subunit C. (275 aa) | ||||
DCTN1 | CAP-Gly domain-containing protein. (1279 aa) | ||||
COX7B2 | Cytochrome c oxidase subunit 7B2. (79 aa) | ||||
VDAC1 | Voltage dependent anion channel 1. (283 aa) | ||||
TUBA4A | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa) | ||||
DCTN6 | Dynactin subunit 6. (190 aa) | ||||
NDUFA4 | Uncharacterized protein. (82 aa) | ||||
ENSFCAP00000038072 | Uncharacterized protein. (92 aa) | ||||
MAPK8 | Mitogen-activated protein kinase. (427 aa) | ||||
CHRNB1 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the ligand-gated ion channel (TC 1.A.9) family. (2274 aa) | ||||
GPX2 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (189 aa) | ||||
GPX3 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (225 aa) | ||||
SEM1 | Uncharacterized protein. (70 aa) | ||||
SDHA | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa) | ||||
PIK3R4 | Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa) | ||||
ATP5PF | ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (116 aa) | ||||
REST | RE1 silencing transcription factor. (1045 aa) | ||||
PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) | ||||
ACTR10 | Actin related protein 10; Belongs to the actin family. (417 aa) | ||||
NDUFB8 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa) | ||||
STX1A | Syntaxin 1A. (334 aa) | ||||
AP2B1 | AP complex subunit beta. (951 aa) | ||||
PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (439 aa) | ||||
LOC105261211 | Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (88 aa) | ||||
LOC101095773 | Cytochrome c oxidase subunit 6A, mitochondrial. (109 aa) | ||||
DNAL4 | Dynein light chain. (105 aa) | ||||
TUBA8 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (481 aa) | ||||
PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) | ||||
GRIN2B | Glutamate ionotropic receptor NMDA type subunit 2B. (1486 aa) | ||||
DNAH12 | Uncharacterized protein. (3945 aa) | ||||
NRF1 | Nuclear respiratory factor 1. (556 aa) | ||||
NDUFB9 | NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (179 aa) | ||||
GRM5 | Glutamate metabotropic receptor 5. (1208 aa) | ||||
BBC3 | Uncharacterized protein. (193 aa) | ||||
MAP2K7 | Mitogen-activated protein kinase kinase 7. (435 aa) | ||||
KCNJ10 | Potassium voltage-gated channel subfamily J member 10. (563 aa) | ||||
DCTN2 | Dynactin subunit 2. (408 aa) | ||||
APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1250 aa) | ||||
POLR2F | RNA polymerase II subunit F. (127 aa) | ||||
MAPK9 | Mitogen-activated protein kinase. (424 aa) | ||||
DNAH7 | Dynein axonemal heavy chain 7. (4023 aa) | ||||
ENSFCAP00000047742 | Uncharacterized protein. (97 aa) | ||||
PSMA4 | Proteasome subunit alpha type. (277 aa) | ||||
SLC25A6 | Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (318 aa) | ||||
PSMD4 | Proteasome 26S subunit, non-ATPase 4. (423 aa) | ||||
PSMB5 | Proteasome subunit beta. (263 aa) | ||||
NDUFS3 | NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (265 aa) | ||||
NDUFV3 | Uncharacterized protein. (107 aa) | ||||
GRIA3 | Glutamate ionotropic receptor AMPA type subunit 3. (894 aa) | ||||
POLR2B | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa) | ||||
BDNF | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (255 aa) | ||||
POLR2L | RNA polymerase II subunit L. (67 aa) | ||||
COX4I1 | Cytochrome c oxidase subunit 4I1. (201 aa) | ||||
HIP1 | Huntingtin interacting protein 1. (1036 aa) | ||||
LOC101095032 | Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (91 aa) | ||||
PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) | ||||
PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa) | ||||
NDUFA4L2 | NDUFA4 mitochondrial complex associated like 2. (91 aa) | ||||
SLC1A2 | Amino acid transporter. (579 aa) | ||||
ATP5F1D | ATP-synt_DE_N domain-containing protein. (282 aa) | ||||
AP2S1 | Adaptor related protein complex 2 subunit sigma 1. (220 aa) | ||||
PSMB1 | Proteasome subunit beta. (261 aa) | ||||
NDUFA9 | NADH:ubiquinone oxidoreductase subunit A9. (389 aa) | ||||
NDUFB4 | NADH:ubiquinone oxidoreductase subunit B4. (132 aa) | ||||
CACNA1B | Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2202 aa) | ||||
DNAH3 | Dynein axonemal heavy chain 3. (4068 aa) | ||||
PSMA3 | Proteasome subunit alpha type. (258 aa) | ||||
GPX6 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (221 aa) | ||||
PPARGC1A | PPARG coactivator 1 alpha. (803 aa) | ||||
DNAH17 | Uncharacterized protein. (799 aa) | ||||
NDUFS4 | NADH:ubiquinone oxidoreductase subunit S4. (187 aa) | ||||
DNAH8 | Dynein axonemal heavy chain 8. (4631 aa) | ||||
CASP8 | Caspase 8; Belongs to the peptidase C14A family. (479 aa) | ||||
PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1209 aa) | ||||
PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1245 aa) | ||||
CREB3 | cAMP responsive element binding protein 3. (399 aa) | ||||
GRIN1 | Glutamate ionotropic receptor NMDA type subunit 1. (1008 aa) | ||||
TGM2 | Transglutaminase 2. (733 aa) | ||||
TAF4 | TATA-box binding protein associated factor 4. (1099 aa) | ||||
VDAC3 | Voltage dependent anion channel 3. (315 aa) | ||||
NRBF2 | Nuclear receptor binding factor 2. (288 aa) | ||||
GRIA4 | Glutamate ionotropic receptor AMPA type subunit 4. (901 aa) | ||||
KLC3 | Kinesin light chain 3. (637 aa) | ||||
PSMB2 | Proteasome subunit beta. (201 aa) | ||||
WIPI1 | WD repeat domain, phosphoinositide interacting 1. (470 aa) | ||||
ATP5MC1 | ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (142 aa) | ||||
PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (477 aa) | ||||
PSMB3 | Proteasome subunit beta. (268 aa) | ||||
CREB3L2 | cAMP responsive element binding protein 3 like 2. (536 aa) | ||||
SDHB | Succinate dehydrogenase complex iron sulfur subunit B. (307 aa) | ||||
NDUFA8 | NADH:ubiquinone oxidoreductase subunit A8. (331 aa) | ||||
UQCRB | Ubiquinol-cytochrome c reductase binding protein. (137 aa) | ||||
NDUFV2 | NADH:ubiquinone oxidoreductase core subunit V2. (256 aa) | ||||
PSMD3 | Proteasome 26S subunit, non-ATPase 3. (595 aa) | ||||
LOC101081808 | Uncharacterized protein. (154 aa) | ||||
DNAH11 | Dynein axonemal heavy chain 11. (4245 aa) | ||||
UQCR10 | Ubiquinol-cytochrome c reductase, complex III subunit X. (182 aa) | ||||
NDUFA10 | NADH:ubiquinone oxidoreductase subunit A10. (442 aa) |