Your Input: | |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | OAS1 | 2'-5'-oligoadenylate synthetase 1. (401 aa) |
| | OAS3 | 2'-5'-oligoadenylate synthetase 3. (1087 aa) |
| | OAS2 | 2'-5'-oligoadenylate synthetase 2. (708 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa) |
| | DDX58 | DExD/H-box helicase 58. (929 aa) |
| | CLDN18 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa) |
| | CLDN20 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa) |
| | JAK1 | Tyrosine-protein kinase. (1157 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | CLDN16 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa) |
| | CTNNB1 | Catenin beta 1. (783 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (606 aa) |
| | IFNB1 | Interferon beta; Has antiviral, antibacterial and anticancer activities. (186 aa) |
| | CLDN6 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa) |
| | CLDN9 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa) |
| | CLDN4 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | E2F1 | E2F transcription factor 1. (436 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (468 aa) |
| | IRF3 | Interferon regulatory factor 3. (420 aa) |
| | EIF2AK2 | Eukaryotic translation initiation factor 2 alpha kinase 2. (541 aa) |
| | NFKBIA | NFKB inhibitor alpha. (314 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (444 aa) |
| | CD81 | Tetraspanin. (236 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (989 aa) |
| | OCLN | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (521 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (167 aa) |
| | TYK2 | Tyrosine-protein kinase. (1181 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (725 aa) |
| | E2F2 | E2F transcription factor 2. (442 aa) |
| | YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa) |
| | STAT2 | Signal transducer and activator of transcription. (855 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1114 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (804 aa) |
| | LOC101095096 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) |
| | LOC101087918 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (718 aa) |
| | MAP2K2 | Protein kinase domain-containing protein. (549 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) |
| | CLDN2 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa) |
| | IRF9 | Interferon regulatory factor 9. (411 aa) |
| | KRAS | Uncharacterized protein. (380 aa) |
| | IFNAR2 | Uncharacterized protein. (519 aa) |
| | CDK4 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (303 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (451 aa) |
| | YWHAZ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa) |
| | CLDN7 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | CLDN17 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa) |
| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | SOCS3 | Suppressor of cytokine signaling 3. (225 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) |
| | LOC101088440 | Uncharacterized protein. (183 aa) |
| | EIF2AK4 | Eukaryotic translation initiation factor 2 alpha kinase 4. (1653 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1; May be involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage (By similarity). Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression (By similarity). Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1 (By similarity). At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity). Inhibits [...] (164 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (423 aa) |
| | PPP2R2D | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (488 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | CLDN11 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa) |
| | LOC101100947 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | CLDN25 | Claudin 25. (228 aa) |
| | CLDN8 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (227 aa) |
| | LOC101087815 | Uncharacterized protein. (219 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | RB1 | RB transcriptional corepressor 1. (930 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | EIF2AK1 | Eukaryotic translation initiation factor 2 alpha kinase 1. (641 aa) |
| | IFNAR1 | Interferon alpha and beta receptor subunit 1. (562 aa) |
| | RNASEL | Ribonuclease L. (724 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the PP2C family. (698 aa) |
| | FAS | Uncharacterized protein. (314 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | YWHAG | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (289 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (917 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (583 aa) |
| | RSAD2 | Radical S-adenosyl methionine domain containing 2. (363 aa) |
| | SCARB1 | Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa) |
| | CASP3 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (302 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | CLDN14 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (238 aa) |
| | IFNA1 | Interferon alpha; Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase; Belongs to the alpha/beta interferon family. (194 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6, membrane form; Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T- cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. [FasL intr [...] (280 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | CLDN1 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | IFNA13 | Uncharacterized protein. (193 aa) |
| | MAVS | Mitochondrial antiviral signaling protein. (662 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1209 aa) |
| | ARAF | A-Raf proto-oncogene, serine/threonine kinase. (659 aa) |
| | TICAM1 | Toll like receptor adaptor molecule 1. (815 aa) |
| | CFLAR | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (508 aa) |
| | PIK3R2 | Phosphoinositide-3-kinase regulatory subunit 2. (726 aa) |
| | CXCL10 | C-X-C motif chemokine. (98 aa) |
| | GSK3B | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (433 aa) |
| | CLDN23 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (291 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (760 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (215 aa) |
| | TRADD | TNFRSF1A associated via death domain. (311 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (439 aa) |
| | IRF7 | Interferon regulatory factor 7. (512 aa) |
| | PIK3R3 | Uncharacterized protein. (461 aa) |
| | CLDN3 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1250 aa) |
| | BAD | BCL2 associated agonist of cell death. (273 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa) |
| | YWHAH | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta. (69 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (555 aa) |
| | YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa) |
| | RXRA | Retinoid X receptor alpha. (654 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (338 aa) |
| | STAT1 | Signal transducer and activator of transcription. (885 aa) |
| | LDLR | Low density lipoprotein receptor. (866 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (321 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (312 aa) |
| | PSME3 | Uncharacterized protein. (265 aa) |
| | NR1H3 | Nuclear receptor subfamily 1 group H member 3. (498 aa) |
| | CLDN15 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (226 aa) |
| | IFIT1 | Interferon induced protein with tetratricopeptide repeats 1. (490 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | PIAS1 | Protein inhibitor of activated STAT 1. (664 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (479 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (205 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (772 aa) |
| | MX1 | MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (675 aa) |
| | YWHAQ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (301 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase. (571 aa) |
| | CLDN19 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (263 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity). (1213 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (774 aa) |
| | PPP2R2C | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (488 aa) |
| | E2F3 | E2F transcription factor 3. (523 aa) |
