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| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | OAS1 | 2'-5'-oligoadenylate synthetase 1. (401 aa) |
| | OAS3 | 2'-5'-oligoadenylate synthetase 3. (1087 aa) |
| | OAS2 | 2'-5'-oligoadenylate synthetase 2. (708 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa) |
| | CALR | Calreticulin. (417 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (478 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (355 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | NFKB2 | Nuclear factor kappa B subunit 2. (921 aa) |
| | DDX58 | DExD/H-box helicase 58. (929 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (410 aa) |
| | SNW1 | SNW domain containing 1. (570 aa) |
| | JAK1 | Tyrosine-protein kinase. (1157 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (467 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (376 aa) |
| | CD19 | CD19 molecule. (641 aa) |
| | NFKBIB | NFKB inhibitor beta. (354 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | IFNB1 | Interferon beta; Has antiviral, antibacterial and anticancer activities. (186 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (421 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | E2F1 | E2F transcription factor 1. (436 aa) |
| | IRF3 | Interferon regulatory factor 3. (420 aa) |
| | EIF2AK2 | Eukaryotic translation initiation factor 2 alpha kinase 2. (541 aa) |
| | PDIA3 | Protein disulfide-isomerase. (505 aa) |
| | NFKBIA | NFKB inhibitor alpha. (314 aa) |
| | JAK3 | Tyrosine-protein kinase. (1232 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (989 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) |
| | NEDD4 | NEDD4 E3 ubiquitin protein ligase. (1323 aa) |
| | ICAM1 | Intercellular adhesion molecule 1. (532 aa) |
| | TYK2 | Tyrosine-protein kinase. (1181 aa) |
| | LOC101090518 | Ig-like domain-containing protein; Belongs to the MHC class II family. (250 aa) |
| | LOC101083591 | Uncharacterized protein. (750 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (724 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (725 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | SIN3A | SIN3 transcription regulator family member A. (1274 aa) |
| | E2F2 | E2F transcription factor 2. (442 aa) |
| | CD3D | CD3d molecule. (170 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (502 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (411 aa) |
| | STAT2 | Signal transducer and activator of transcription. (855 aa) |
| | B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (118 aa) |
| | GADD45B | Growth arrest and DNA damage inducible beta. (234 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (718 aa) |
| | MAP3K14 | Mitogen-activated protein kinase kinase kinase 14. (954 aa) |
| | ENTPD1 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (510 aa) |
| | CD40 | CD40 molecule. (324 aa) |
| | SYK | Spleen associated tyrosine kinase. (636 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | IRF9 | Interferon regulatory factor 9. (411 aa) |
| | LOC105260551 | Ig-like domain-containing protein; Belongs to the MHC class I family. (438 aa) |
| | SAP30 | Sin3A associated protein 30. (221 aa) |
| | IFNAR2 | Uncharacterized protein. (519 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (324 aa) |
| | CDK4 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (303 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (451 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (492 aa) |
| | CIR1 | Corepressor interacting with RBPJ, 1. (471 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | LOC101088440 | Uncharacterized protein. (183 aa) |
| | TLR2 | Toll like receptor 2; Belongs to the Toll-like receptor family. (784 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1; May be involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage (By similarity). Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression (By similarity). Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1 (By similarity). At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity). Inhibits [...] (164 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (423 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa) |
| | PSMD12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (406 aa) |
| | LYN | Tyrosine-protein kinase. (526 aa) |
| | LOC101100947 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | RBPJ | Recombination signal binding protein for immunoglobulin kappa J region. (500 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | RB1 | RB transcriptional corepressor 1. (930 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1. Permits the nuclear export of p53/TP53. Promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 protein. Inhibits DAXX-mediated apoptosis by inducing its ubiquitination and degradation. Component of the TRIM28/KAP1-MDM2-p53/TP53 [...] (712 aa) |
| | IFNAR1 | Interferon alpha and beta receptor subunit 1. (562 aa) |
| | LOC101099296 | Ig-like domain-containing protein; Belongs to the MHC class I family. (357 aa) |
| | RELB | RELB proto-oncogene, NF-kB subunit. (582 aa) |
| | FAS | Uncharacterized protein. (314 aa) |
| | RUNX3 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (426 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | ENTPD3 | Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (529 aa) |
| | LOC101080790 | MHC_I-like_Ag-recog domain-containing protein. (216 aa) |
| | POLK | DNA polymerase kappa. (863 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (367 aa) |
| | CASP3 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (302 aa) |
| | IFNA1 | Interferon alpha; Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase; Belongs to the alpha/beta interferon family. (194 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (498 aa) |
| | SLC26A3-2 | Ig-like domain-containing protein; Belongs to the MHC class II family. (254 aa) |
| | USP7 | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1107 aa) |
| | LOC101089770 | Uncharacterized protein. (715 aa) |
| | HDAC2 | Histone deacetylase 2. (602 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | ISG15 | ISG15 ubiquitin like modifier. (157 aa) |
| | PSMC1 | AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (308 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | LOC101082653 | Ig-like domain-containing protein. (276 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (292 aa) |
| | IFNA13 | Uncharacterized protein. (193 aa) |
| | BLNK | B cell linker. (479 aa) |
| | SAP30L | SAP30 like. (182 aa) |
| | SEM1 | Uncharacterized protein. (70 aa) |
| | MAVS | Mitochondrial antiviral signaling protein. (662 aa) |
| | LOC101084962 | Ig-like domain-containing protein. (253 aa) |
| | LOC101090265 | Ig-like domain-containing protein. (263 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1318 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) |
| | BTK | Tyrosine-protein kinase. (692 aa) |
| | LOC111556311 | Uncharacterized protein. (857 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (439 aa) |
| | PIK3R2 | Phosphoinositide-3-kinase regulatory subunit 2. (726 aa) |
| | CXCL10 | C-X-C motif chemokine. (98 aa) |
| | RBPJL | Recombination signal binding protein for immunoglobulin kappa J region like. (597 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | CDKN1B | Cyclin-dependent kinase inhibitor 1B; Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. (198 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (760 aa) |
| | LOC111558970 | Ig-like domain-containing protein; Belongs to the MHC class II family. (254 aa) |
| | FLAI-K | Ig-like domain-containing protein; Belongs to the MHC class I family. (406 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (215 aa) |
| | LOC101082906 | Ig-like domain-containing protein. (282 aa) |
| | TRADD | TNFRSF1A associated via death domain. (311 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (439 aa) |
| | IRF7 | Interferon regulatory factor 7. (512 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (435 aa) |
| | PIK3R3 | Uncharacterized protein. (461 aa) |
| | LOC101090771 | Ig-like domain-containing protein; Belongs to the MHC class II family. (257 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1250 aa) |
| | ENTPD8 | Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family. (501 aa) |
| | GADD45G | Growth arrest and DNA damage inducible gamma. (159 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | ENSFCAP00000047742 | Uncharacterized protein. (97 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (555 aa) |
| | NFKBIE | NFKB inhibitor epsilon. (362 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (423 aa) |
| | LOC101091023 | Ig-like domain-containing protein. (452 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (338 aa) |
| | VIM | Vimentin; Belongs to the intermediate filament family. (466 aa) |
| | STAT1 | Signal transducer and activator of transcription. (885 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (321 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (280 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (312 aa) |
| | LOC111560444 | Ig-like domain-containing protein; Belongs to the MHC class II family. (250 aa) |
| | LOC111556177 | Ig-like domain-containing protein; Belongs to the MHC class I family. (499 aa) |
| | LOC101084108 | Ig-like domain-containing protein; Belongs to the MHC class II family. (344 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | LOC101094232 | Ig-like domain-containing protein; Belongs to the MHC class I family. (461 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (479 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (205 aa) |
| | CR2 | Complement C3d receptor 2. (1474 aa) |
| | TAPBP | Ig-like domain-containing protein. (452 aa) |
| | TNFAIP3 | TNF alpha induced protein 3. (804 aa) |
| | LOC111556169 | Ig-like domain-containing protein. (276 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (477 aa) |
| | LOC111559549 | Ig-like domain-containing protein. (247 aa) |
| | LOC111560443 | Ig-like domain-containing protein; Belongs to the MHC class II family. (322 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase. (571 aa) |
| | FCER2 | Fc fragment of IgE receptor II. (290 aa) |
| | SKP2 | S-phase kinase associated protein 2. (451 aa) |
| | CD58 | Uncharacterized protein. (270 aa) |
| | MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (383 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (774 aa) |
| | ITGAL | Integrin subunit alpha L; Belongs to the integrin alpha chain family. (1290 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (595 aa) |
| | CD247 | CD247 molecule. (250 aa) |
| | BCL2 | BCL2 apoptosis regulator. (237 aa) |
| | E2F3 | E2F transcription factor 3. (523 aa) |
