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CYP1A2 CYP1A2 MGST3 MGST3 ADH5 ADH5 ALDH3A1 ALDH3A1 LOC101096317 LOC101096317 KYAT1 KYAT1 GSTK1 GSTK1 KYAT3 KYAT3 LOC101089816 LOC101089816 HSD11B1L HSD11B1L GSTM3 GSTM3 M3WQB1_FELCA M3WQB1_FELCA UGT1A UGT1A GSTO1 GSTO1 ALDH3B1 ALDH3B1 LOC101083370 LOC101083370 PTGS2 PTGS2 MGST2 MGST2 LOC101100387 LOC101100387 LOC101084793 LOC101084793 HSD11B1 HSD11B1 GSTM4 GSTM4 LOC101083114 LOC101083114 GSTT4 GSTT4 EPHX1 EPHX1 LOC101084134 LOC101084134 GSTA4 GSTA4 LOC101083875 LOC101083875 LOC101088902 LOC101088902 LOC105259649 LOC105259649 ARNT ARNT CYP3A131 CYP3A131 CYP2E2 CYP2E2 LOC101095575 LOC101095575 LOC105260134 LOC105260134 CYP1B1 CYP1B1 LOC101089561 LOC101089561 CHRNA7 CHRNA7 HPGDS HPGDS GSTP1 GSTP1 LOC101087662 LOC101087662 MGST1 MGST1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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CYP1A2Cytochrome P450 1A2; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E [...] (512 aa)
MGST3Microsomal glutathione S-transferase 3. (190 aa)
ADH5S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
ALDH3A1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (478 aa)
LOC101096317Uncharacterized protein; Belongs to the GST superfamily. (223 aa)
KYAT1Aminotran_1_2 domain-containing protein. (458 aa)
GSTK1Glutathione S-transferase kappa 1. (423 aa)
KYAT3Kynurenine aminotransferase 3. (455 aa)
LOC101089816Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
HSD11B1LHydroxysteroid 11-beta dehydrogenase 1 like. (302 aa)
GSTM3Glutathione S-transferase. (226 aa)
M3WQB1_FELCAUncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (283 aa)
UGT1AUDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (533 aa)
GSTO1Glutathione S-transferase omega 1. (241 aa)
ALDH3B1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (489 aa)
LOC101083370Uncharacterized protein. (257 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
MGST2Microsomal glutathione S-transferase 2. (146 aa)
LOC101100387PKS_ER domain-containing protein. (375 aa)
LOC101084793Uncharacterized protein. (222 aa)
HSD11B1Hydroxysteroid 11-beta dehydrogenase 1. (292 aa)
GSTM4Glutathione S-transferase mu 4; Belongs to the GST superfamily. (212 aa)
LOC101083114Uncharacterized protein; Belongs to the GST superfamily. (296 aa)
GSTT4Glutathione S-transferase theta 4; Belongs to the GST superfamily. (274 aa)
EPHX1Epoxide hydrolase 1. (565 aa)
LOC101084134Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (292 aa)
GSTA4Glutathione S-transferase alpha 4. (222 aa)
LOC101083875Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (292 aa)
LOC101088902Sulfotransferase; Belongs to the sulfotransferase 1 family. (295 aa)
LOC105259649Uncharacterized protein; Belongs to the cytochrome P450 family. (552 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (790 aa)
CYP3A131Uncharacterized protein. (503 aa)
CYP2E2Uncharacterized protein; Belongs to the cytochrome P450 family. (495 aa)
LOC101095575Arylamine N-acetyltransferase 1; Participates in the detoxification of a plethora of hydrazine and arylamine drugs. (290 aa)
LOC105260134Uncharacterized protein; Belongs to the cytochrome P450 family. (498 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (553 aa)
LOC101089561Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
CHRNA7Uncharacterized protein. (499 aa)
HPGDSHematopoietic prostaglandin D synthase; Belongs to the GST superfamily. (199 aa)
GSTP1Uncharacterized protein; Belongs to the GST superfamily. (438 aa)
LOC101087662UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family. (555 aa)
MGST1Microsomal glutathione S-transferase 1. (176 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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