(18 nodes) T cell apoptotic process network (Panthera pardus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ADA	Adenosine deaminase isoform X1. (363 aa)
	BAK1	Bcl-2 homologous antagonist/killer. (211 aa)
	IL2RA	Interleukin-2 receptor subunit alpha isoform X1. (268 aa)
	GLI3	Transcriptional activator GLI3 isoform X1. (1572 aa)
	BCL3	B-cell lymphoma 3 protein isoform X1. (454 aa)
	BCL11B	LOW QUALITY PROTEIN: B-cell lymphoma/leukemia 11B. (838 aa)
	CHEK2	Serine/threonine-protein kinase Chk2 isoform X1. (538 aa)
	BCL2L11	Bcl-2-like protein 11 isoform X1. (197 aa)
	GPAM	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
	ENSPPRP00000007447	annotation not available (205 aa)
	LMBR1L	Protein LMBR1L isoform X1. (489 aa)
	BBC3	Bcl-2-binding component 3. (127 aa)
	BCL10	B-cell lymphoma/leukemia 10. (233 aa)
	KIFAP3	Kinesin-associated protein 3 isoform X1. (793 aa)
	RIPK1	Receptor-interacting serine/threonine-protein kinase 1. (671 aa)
	FASLG	Tumor necrosis factor ligand superfamily member 6. (278 aa)
	FAS	Fas cell surface death receptor. (293 aa)
	TP53	Cellular tumor antigen p53. (386 aa)

Your Current Organism:

Panthera pardus

NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAK1	BBC3	ENSPPRP00000022494	ENSPPRP00000004989	Bcl-2 homologous antagonist/killer.	Bcl-2-binding component 3.	0.676
BAK1	BCL2L11	ENSPPRP00000022494	ENSPPRP00000011605	Bcl-2 homologous antagonist/killer.	Bcl-2-like protein 11 isoform X1.	0.848
BAK1	TP53	ENSPPRP00000022494	ENSPPRP00000022844	Bcl-2 homologous antagonist/killer.	Cellular tumor antigen p53.	0.962
BBC3	BAK1	ENSPPRP00000004989	ENSPPRP00000022494	Bcl-2-binding component 3.	Bcl-2 homologous antagonist/killer.	0.676
BBC3	BCL2L11	ENSPPRP00000004989	ENSPPRP00000011605	Bcl-2-binding component 3.	Bcl-2-like protein 11 isoform X1.	0.948
BBC3	ENSPPRP00000007447	ENSPPRP00000004989	ENSPPRP00000007447	Bcl-2-binding component 3.	annotation not available	0.676
BBC3	TP53	ENSPPRP00000004989	ENSPPRP00000022844	Bcl-2-binding component 3.	Cellular tumor antigen p53.	0.676
BCL2L11	BAK1	ENSPPRP00000011605	ENSPPRP00000022494	Bcl-2-like protein 11 isoform X1.	Bcl-2 homologous antagonist/killer.	0.848
BCL2L11	BBC3	ENSPPRP00000011605	ENSPPRP00000004989	Bcl-2-like protein 11 isoform X1.	Bcl-2-binding component 3.	0.948
BCL2L11	ENSPPRP00000007447	ENSPPRP00000011605	ENSPPRP00000007447	Bcl-2-like protein 11 isoform X1.	annotation not available	0.848
BCL2L11	FASLG	ENSPPRP00000011605	ENSPPRP00000028469	Bcl-2-like protein 11 isoform X1.	Tumor necrosis factor ligand superfamily member 6.	0.445
CHEK2	TP53	ENSPPRP00000011735	ENSPPRP00000022844	Serine/threonine-protein kinase Chk2 isoform X1.	Cellular tumor antigen p53.	0.994
ENSPPRP00000007447	BBC3	ENSPPRP00000007447	ENSPPRP00000004989	annotation not available	Bcl-2-binding component 3.	0.676
ENSPPRP00000007447	BCL2L11	ENSPPRP00000007447	ENSPPRP00000011605	annotation not available	Bcl-2-like protein 11 isoform X1.	0.848
ENSPPRP00000007447	TP53	ENSPPRP00000007447	ENSPPRP00000022844	annotation not available	Cellular tumor antigen p53.	0.643
FAS	FASLG	ENSPPRP00000023896	ENSPPRP00000028469	Fas cell surface death receptor.	Tumor necrosis factor ligand superfamily member 6.	0.991
FAS	RIPK1	ENSPPRP00000023896	ENSPPRP00000001555	Fas cell surface death receptor.	Receptor-interacting serine/threonine-protein kinase 1.	0.757
FASLG	BCL2L11	ENSPPRP00000028469	ENSPPRP00000011605	Tumor necrosis factor ligand superfamily member 6.	Bcl-2-like protein 11 isoform X1.	0.445
FASLG	FAS	ENSPPRP00000028469	ENSPPRP00000023896	Tumor necrosis factor ligand superfamily member 6.	Fas cell surface death receptor.	0.991
FASLG	RIPK1	ENSPPRP00000028469	ENSPPRP00000001555	Tumor necrosis factor ligand superfamily member 6.	Receptor-interacting serine/threonine-protein kinase 1.	0.712