STRINGSTRING
CFLAR CFLAR CASP8 CASP8 CASP10 CASP10 RIPK1 RIPK1 FADD FADD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CFLARCASP8 and FADD-like apoptosis regulator isoform X1. (481 aa)
CASP8Caspase-8 isoform X1. (464 aa)
CASP10Caspase 10. (521 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (671 aa)
FADDFas associated via death domain. (199 aa)
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.