STRINGSTRING
ADCY7 ADCY7 MTOR MTOR ATG13 ATG13 CREB3L2 CREB3L2 AKT2 AKT2 PRKACA PRKACA PIK3R1 PIK3R1 FOXO1 FOXO1 ADIPOR1 ADIPOR1 ADCY8 ADCY8 ADCY3 ADCY3 EHMT2 EHMT2 SESN2 SESN2 LOC109253093 LOC109253093 EHMT1 EHMT1 ATF4 ATF4 ATF2 ATF2 PIK3CB PIK3CB PPARGC1A PPARGC1A PPARG PPARG ADCY6 ADCY6 TSC1 TSC1 CREB5 CREB5 EIF4E2 EIF4E2 ADCY2 ADCY2 RELA RELA PIK3CA PIK3CA PRKAB1 PRKAB1 SESN3 SESN3 ADIPOQ ADIPOQ CREB3L3 CREB3L3 CAT CAT NFKB1 NFKB1 STK11 STK11 ADCY1 ADCY1 CREB1 CREB1 PIK3R2 PIK3R2 CREB3L1 CREB3L1 NRAS NRAS PRKAA2 PRKAA2 CAMK4 CAMK4 RPS6KB1 RPS6KB1 KRAS KRAS PRKAA1 PRKAA1 IGF1R IGF1R KL KL ADIPOR2 ADIPOR2 CAMKK2 CAMKK2 HRAS HRAS AKT1 AKT1 EIF4EBP1 EIF4EBP1 PIK3R3 PIK3R3 PRKAG3 PRKAG3 AKT3 AKT3 PRKAG1 PRKAG1 INSR INSR APPL1 APPL1 PRKAB2 PRKAB2 ADCY9 ADCY9 ATF6B ATF6B AKT1S1 AKT1S1 RPS6KB2 RPS6KB2 EIF4E1B EIF4E1B SESN1 SESN1 ADCY5 ADCY5 ATG5 ATG5 CREB3 CREB3 SIRT1 SIRT1 INS INS TP53 TP53 RB1CC1 RB1CC1 ATG101 ATG101 IRS4 IRS4 IRS1 IRS1 FOXO3 FOXO3 PRKACB PRKACB TSC2 TSC2 RHEB RHEB SOD2 SOD2 ADCY4 ADCY4 EIF4E EIF4E RPTOR RPTOR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADCY7Adenylate cyclase type 7 isoform X1. (1060 aa)
MTORSerine/threonine-protein kinase mTOR. (2550 aa)
ATG13Autophagy-related protein 13 isoform X1. (550 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X1. (520 aa)
AKT2RAC-beta serine/threonine-protein kinase. (481 aa)
PRKACACAMP-dependent protein kinase catalytic subunit alpha isoform X1. (351 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
FOXO1Forkhead box protein O1. (655 aa)
ADIPOR1Adiponectin receptor protein 1. (375 aa)
ADCY8Adenylate cyclase type 8 isoform X1. (1252 aa)
ADCY3Adenylate cyclase type 3 isoform X1. (1145 aa)
EHMT2Histone-lysine N-methyltransferase EHMT2 isoform X1. (1268 aa)
SESN2Sestrin 2. (482 aa)
LOC109253093Apoptosis regulator BAX isoform X1. (192 aa)
EHMT1Histone-lysine N-methyltransferase EHMT1 isoform X1. (1297 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (352 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta. (1070 aa)
PPARGC1APeroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1. (796 aa)
PPARGPeroxisome proliferator-activated receptor gamma isoform X1. (505 aa)
ADCY6Adenylate cyclase type 6. (1164 aa)
TSC1Tuberous sclerosis 1. (1161 aa)
CREB5Cyclic AMP-responsive element-binding protein 5 isoform X1. (506 aa)
EIF4E2Eukaryotic translation initiation factor 4E type 2 isoform X1. (245 aa)
ADCY2Adenylate cyclase type 2 isoform X1. (1097 aa)
RELATranscription factor p65 isoform X1. (553 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta. (1068 aa)
PRKAB15'-AMP-activated protein kinase, regulatory beta subunit. (270 aa)
SESN3Sestrin 1/3. (492 aa)
ADIPOQAdiponectin isoform X1. (244 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1. (449 aa)
CATCatalase. (527 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (968 aa)
STK11Serine/threonine-protein kinase STK11 isoform X1. (439 aa)
ADCY1Adenylate cyclase type 1. (1120 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
PIK3R2Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta. (726 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
NRASGTPase NRas. (189 aa)
PRKAA25'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X1. (552 aa)
CAMK4Calcium/calmodulin-dependent protein kinase type IV isoform X1. (473 aa)
RPS6KB1Ribosomal protein S6 kinase beta-1 isoform X1. (525 aa)
KRASGTPase KRas isoform X1. (189 aa)
PRKAA15'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X1. (574 aa)
IGF1RInsulin-like growth factor 1 receptor. (1367 aa)
KLLOW QUALITY PROTEIN: klotho. (1007 aa)
ADIPOR2Adiponectin receptor protein 2. (386 aa)
CAMKK2Calcium/calmodulin-dependent protein kinase kinase 2 isoform X1. (580 aa)
HRASGTPase HRas. (171 aa)
AKT1RAC-alpha serine/threonine-protein kinase isoform X1. (480 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E-binding protein 1 isoform X1. (118 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta. (461 aa)
PRKAG35'-AMP-activated protein kinase subunit gamma-3 isoform X1. (485 aa)
AKT3RAC-gamma serine/threonine-protein kinase isoform X1. (479 aa)
PRKAG15'-AMP-activated protein kinase subunit gamma-1 isoform X1. (298 aa)
INSRInsulin receptor isoform X1. (1381 aa)
APPL1DCC-interacting protein 13-alpha isoform X1. (698 aa)
PRKAB25'-AMP-activated protein kinase subunit beta-2 isoform X1. (272 aa)
ADCY9Adenylate cyclase type 9. (1352 aa)
ATF6BCyclic AMP-dependent transcription factor ATF-6 beta isoform X1. (704 aa)
AKT1S1Proline-rich AKT1 substrate 1 isoform X1. (276 aa)
RPS6KB2Ribosomal protein S6 kinase beta-2 isoform X1. (467 aa)
EIF4E1BEukaryotic translation initiation factor 4E type 1B. (247 aa)
SESN1Sestrin-1 isoform X1. (551 aa)
ADCY5Adenylate cyclase type 5 isoform X1. (1263 aa)
ATG5Autophagy protein 5 isoform X1. (275 aa)
CREB3Cyclic AMP-responsive element-binding protein 3. (353 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (745 aa)
INSInsulin. (110 aa)
TP53Cellular tumor antigen p53. (386 aa)
RB1CC1RB1-inducible coiled-coil protein 1 isoform X1. (1593 aa)
ATG101Autophagy-related protein 101. (212 aa)
IRS4Insulin receptor substrate 4. (1251 aa)
IRS1Insulin receptor substrate 1. (1234 aa)
FOXO3Forkhead box protein O3. (672 aa)
PRKACBCAMP-dependent protein kinase catalytic subunit beta isoform X1. (397 aa)
TSC2Tuberous sclerosis 2. (1808 aa)
RHEBGTP-binding protein Rheb isoform X1. (184 aa)
SOD2Superoxide dismutase [Mn], mitochondrial. (222 aa)
ADCY4Adenylate cyclase type 4 isoform X1. (1077 aa)
EIF4EEukaryotic translation initiation factor 4E isoform X1. (237 aa)
RPTORRegulatory-associated protein of mTOR isoform X1. (1335 aa)
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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