STRINGSTRING
ADCY7 ADCY7 MTOR MTOR AKT2 AKT2 PRKACA PRKACA PIK3R1 PIK3R1 FOXO1 FOXO1 ADCY8 ADCY8 ADCY3 ADCY3 CLPB CLPB PIK3CB PIK3CB SOD1 SOD1 HDAC2 HDAC2 ADCY6 ADCY6 ADCY2 ADCY2 PIK3CA PIK3CA PRKAB1 PRKAB1 CAT CAT HSPA8 HSPA8 ADCY1 ADCY1 PIK3R2 PIK3R2 NRAS NRAS PRKAA2 PRKAA2 RPS6KB1 RPS6KB1 KRAS KRAS PRKAA1 PRKAA1 CRYAB CRYAB IGF1R IGF1R HRAS HRAS AKT1 AKT1 PIK3R3 PIK3R3 PRKAG3 PRKAG3 AKT3 AKT3 PRKAG1 PRKAG1 FOXA2 FOXA2 INSR INSR PRKAB2 PRKAB2 ADCY9 ADCY9 AKT1S1 AKT1S1 RPS6KB2 RPS6KB2 HDAC1 HDAC1 ADCY5 ADCY5 ATG5 ATG5 SIRT1 SIRT1 INS INS IRS4 IRS4 IRS1 IRS1 FOXO3 FOXO3 PRKACB PRKACB ENSPPRP00000025712 ENSPPRP00000025712 EIF4EBP2 EIF4EBP2 SOD2 SOD2 ADCY4 ADCY4 RPTOR RPTOR HSPA2 HSPA2 HSPA1L HSPA1L HSPA1A HSPA1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADCY7Adenylate cyclase type 7 isoform X1. (1060 aa)
MTORSerine/threonine-protein kinase mTOR. (2550 aa)
AKT2RAC-beta serine/threonine-protein kinase. (481 aa)
PRKACACAMP-dependent protein kinase catalytic subunit alpha isoform X1. (351 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
FOXO1Forkhead box protein O1. (655 aa)
ADCY8Adenylate cyclase type 8 isoform X1. (1252 aa)
ADCY3Adenylate cyclase type 3 isoform X1. (1145 aa)
CLPBATP-dependent Clp protease ATP-binding subunit ClpB. (706 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta. (1070 aa)
SOD1Superoxide dismutase, Cu-Zn family. (153 aa)
HDAC2Histone deacetylase 2 isoform X1. (488 aa)
ADCY6Adenylate cyclase type 6. (1164 aa)
ADCY2Adenylate cyclase type 2 isoform X1. (1097 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta. (1068 aa)
PRKAB15'-AMP-activated protein kinase, regulatory beta subunit. (270 aa)
CATCatalase. (527 aa)
HSPA8Heat shock cognate 71 kDa protein. (646 aa)
ADCY1Adenylate cyclase type 1. (1120 aa)
PIK3R2Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta. (726 aa)
NRASGTPase NRas. (189 aa)
PRKAA25'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X1. (552 aa)
RPS6KB1Ribosomal protein S6 kinase beta-1 isoform X1. (525 aa)
KRASGTPase KRas isoform X1. (189 aa)
PRKAA15'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X1. (574 aa)
CRYABAlpha-crystallin B chain. (175 aa)
IGF1RInsulin-like growth factor 1 receptor. (1367 aa)
HRASGTPase HRas. (171 aa)
AKT1RAC-alpha serine/threonine-protein kinase isoform X1. (480 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta. (461 aa)
PRKAG35'-AMP-activated protein kinase subunit gamma-3 isoform X1. (485 aa)
AKT3RAC-gamma serine/threonine-protein kinase isoform X1. (479 aa)
PRKAG15'-AMP-activated protein kinase subunit gamma-1 isoform X1. (298 aa)
FOXA2Forkhead box protein A2, hepatocyte nuclear factor 3-beta. (456 aa)
INSRInsulin receptor isoform X1. (1381 aa)
PRKAB25'-AMP-activated protein kinase subunit beta-2 isoform X1. (272 aa)
ADCY9Adenylate cyclase type 9. (1352 aa)
AKT1S1Proline-rich AKT1 substrate 1 isoform X1. (276 aa)
RPS6KB2Ribosomal protein S6 kinase beta-2 isoform X1. (467 aa)
HDAC1Histone deacetylase 1 isoform X1. (481 aa)
ADCY5Adenylate cyclase type 5 isoform X1. (1263 aa)
ATG5Autophagy protein 5 isoform X1. (275 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (745 aa)
INSInsulin. (110 aa)
IRS4Insulin receptor substrate 4. (1251 aa)
IRS1Insulin receptor substrate 1. (1234 aa)
FOXO3Forkhead box protein O3. (672 aa)
PRKACBCAMP-dependent protein kinase catalytic subunit beta isoform X1. (397 aa)
ENSPPRP00000025712Heat shock 70 kDa protein 1B-like. (476 aa)
EIF4EBP2Eukaryotic translation initiation factor 4E binding protein 2. (106 aa)
SOD2Superoxide dismutase [Mn], mitochondrial. (222 aa)
ADCY4Adenylate cyclase type 4 isoform X1. (1077 aa)
RPTORRegulatory-associated protein of mTOR isoform X1. (1335 aa)
HSPA2Heat shock-related 70 kDa protein 2. (639 aa)
HSPA1LHeat shock 70 kDa protein 1-like. (641 aa)
HSPA1AHeat shock 70 kDa protein 1A isoform X1. (641 aa)
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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