32 items (Odobenus rosmarus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PNPLA8	Calcium-independent phospholipase A2-gamma isoform X1. (781 aa)
	TPRA1	Transmembrane protein adipocyte-associated 1. (367 aa)
	ADIPOQ	Adiponectin isoform X1. (266 aa)
	EMG1	Ribosomal RNA small subunit methyltransferase NEP1. (244 aa)
	ADIG	Adipogenin. (73 aa)
	THAP1	THAP domain-containing protein 1. (213 aa)
	LOC101384189	Cytochrome c oxidase subunit 7A1, mitochondrial. (80 aa)
	THY1	Thy-1 membrane glycoprotein. (161 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (529 aa)
	LOC101375046	Cytochrome c oxidase subunit 7A1, mitochondrial. (80 aa)
	LEP	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
	SLC2A4	Solute carrier family 2, facilitated glucose transporter member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (508 aa)
	BOLA3	bolA-like protein 3 isoform X1; Belongs to the BolA/IbaG family. (110 aa)
	ACP2	Lysosomal acid phosphatase isoform X1; Belongs to the histidine acid phosphatase family. (423 aa)
	MRPL30	39S ribosomal protein L30, mitochondrial. (161 aa)
	LOC101383672	Cytochrome c oxidase protein 20 homolog. (119 aa)
	PNPLA2	Patatin-like phospholipase domain-containing protein 2. (486 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	TUSC5	Tumor suppressor candidate 5. (230 aa)
	CEBPA	CCAAT/enhancer-binding protein alpha. (354 aa)
	ABCC9	ATP-binding cassette sub-family C member 9 isoform X2. (1549 aa)
	VCAN	Versican core protein isoform X1. (3400 aa)
	ASB14	Ankyrin repeat and SOCS box protein 14. (587 aa)
	LOC101373381	Bombesin receptor-activated protein C6orf89 homolog isoform X1. (387 aa)
	RRAS	Ras-related protein R-Ras. (218 aa)
	ACPT	Testicular acid phosphatase; Belongs to the histidine acid phosphatase family. (426 aa)
	LDB3	LIM domain-binding protein 3 isoform X1. (725 aa)
	MANF	Mesencephalic astrocyte-derived neurotrophic factor. (179 aa)
	FABP4	Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	RSU1	Ras suppressor protein 1 isoform X1. (277 aa)
	ENG	Endoglin. (659 aa)
	SLC25A51	Solute carrier family 25 member 51; Belongs to the mitochondrial carrier (TC 2.A.29) family. (297 aa)

Your Current Organism:

Odobenus rosmarus

NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADIG	ADIPOQ	A0A2U3X046	A0A2U3WVI3	Adipogenin.	Adiponectin isoform X1.	0.452
ADIPOQ	ADIG	A0A2U3WVI3	A0A2U3X046	Adiponectin isoform X1.	Adipogenin.	0.452
ADIPOQ	CEBPA	A0A2U3WVI3	A0A2U3WAN3	Adiponectin isoform X1.	CCAAT/enhancer-binding protein alpha.	0.692
ADIPOQ	FABP4	A0A2U3WVI3	A0A2U3VGA8	Adiponectin isoform X1.	Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.968
ADIPOQ	INS	A0A2U3WVI3	A0A2U3W6R9	Adiponectin isoform X1.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.767
ADIPOQ	LEP	A0A2U3WVI3	A0A2U3VS59	Adiponectin isoform X1.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	0.916
ADIPOQ	PPARG	A0A2U3WVI3	A0A2U3VLH3	Adiponectin isoform X1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.779
ADIPOQ	SLC2A4	A0A2U3WVI3	A0A2U3VTD2	Adiponectin isoform X1.	Solute carrier family 2, facilitated glucose transporter member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.763
CEBPA	ADIPOQ	A0A2U3WAN3	A0A2U3WVI3	CCAAT/enhancer-binding protein alpha.	Adiponectin isoform X1.	0.692
CEBPA	FABP4	A0A2U3WAN3	A0A2U3VGA8	CCAAT/enhancer-binding protein alpha.	Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.624
CEBPA	INS	A0A2U3WAN3	A0A2U3W6R9	CCAAT/enhancer-binding protein alpha.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.519
CEBPA	LEP	A0A2U3WAN3	A0A2U3VS59	CCAAT/enhancer-binding protein alpha.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	0.531
CEBPA	PPARG	A0A2U3WAN3	A0A2U3VLH3	CCAAT/enhancer-binding protein alpha.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.797
CEBPA	SLC2A4	A0A2U3WAN3	A0A2U3VTD2	CCAAT/enhancer-binding protein alpha.	Solute carrier family 2, facilitated glucose transporter member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.537
ENG	THY1	A0A2U3VDC0	A0A2U3ZT56	Endoglin.	Thy-1 membrane glycoprotein.	0.760
FABP4	ADIPOQ	A0A2U3VGA8	A0A2U3WVI3	Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Adiponectin isoform X1.	0.968
FABP4	CEBPA	A0A2U3VGA8	A0A2U3WAN3	Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	CCAAT/enhancer-binding protein alpha.	0.624
FABP4	INS	A0A2U3VGA8	A0A2U3W6R9	Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.631
FABP4	LEP	A0A2U3VGA8	A0A2U3VS59	Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	0.620
FABP4	PNPLA2	A0A2U3VGA8	A0A2U3W6N1	Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Patatin-like phospholipase domain-containing protein 2.	0.523