STRINGSTRING
NKX6-1 NKX6-1 SLC2A2 SLC2A2 NKX6-2 NKX6-2 GIP GIP INS INS FAP FAP GCG GCG DPP4 DPP4 GLP1R GLP1R SLC30A8 SLC30A8 IAPP IAPP GCK GCK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NKX6-1Homeobox protein Nkx-6.1. (368 aa)
SLC2A2Solute carrier family 2, facilitated glucose transporter member 2 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
NKX6-2Homeobox protein Nkx-6.2. (276 aa)
GIPGastric inhibitory polypeptide. (145 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
FAPProlyl endopeptidase FAP isoform X1; Belongs to the peptidase S9B family. (760 aa)
GCGGlucagon. (180 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (794 aa)
GLP1RGlucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
SLC30A8Zinc transporter 8. (369 aa)
IAPPIslet amyloid polypeptide. (89 aa)
GCKPhosphotransferase. (458 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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