STRINGSTRING
THY1 THY1 PDE3B PDE3B ZNF449 ZNF449 TMEM254 TMEM254 SH3GLB2 SH3GLB2 LOC101384189 LOC101384189 FAM45A FAM45A LOC101364305 LOC101364305 DAD1 DAD1 CD300LG CD300LG ANO6 ANO6 LOC101375928 LOC101375928 KIF16B KIF16B ACACB ACACB THAP1 THAP1 SMAP2 SMAP2 ADIG ADIG ARMCX6 ARMCX6 EMG1 EMG1 ROBO4 ROBO4 ADIPOQ ADIPOQ MRPL17 MRPL17 PRIMPOL PRIMPOL RETN RETN ANGPTL4 ANGPTL4 PNPLA8 PNPLA8 MANF MANF SMIM4 SMIM4 DNLZ DNLZ ADIRF ADIRF LDB3 LDB3 ACPT ACPT RRAS RRAS LOC101373381 LOC101373381 GALNT15 GALNT15 CNEP1R1 CNEP1R1 LIPE LIPE ICE2 ICE2 TMEM41A TMEM41A ASB14 ASB14 FABP3 FABP3 MRPS6 MRPS6 UCP1 UCP1 VCAN VCAN ABCC9 ABCC9 CEBPA CEBPA EPN2 EPN2 MCUR1 MCUR1 TUSC5 TUSC5 TIMM22 TIMM22 INS INS PNPLA2 PNPLA2 GZMK GZMK EVA1B EVA1B METTL17 METTL17 SCD SCD MKNK1 MKNK1 SCARF2 SCARF2 LOC101383672 LOC101383672 YIPF1 YIPF1 MRPL30 MRPL30 ACP2 ACP2 BOLA3 BOLA3 SLC2A4 SLC2A4 LOC101380962 LOC101380962 PLIN1 PLIN1 LEP LEP ACACA ACACA SERHL2 SERHL2 LOC101375046 LOC101375046 PPARG PPARG TPRA1 TPRA1 CFD CFD RPS15 RPS15 RSAD1 RSAD1 C3 C3 COPZ2 COPZ2 MRPL45 MRPL45 ADRB3 ADRB3 ICT1 ICT1 PELI3 PELI3 FABP4 FABP4 RSU1 RSU1 ENG ENG SLC25A51 SLC25A51 CREBRF CREBRF UCP2 UCP2 UCP3 UCP3 RETNLB RETNLB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
THY1Thy-1 membrane glycoprotein. (161 aa)
PDE3BPhosphodiesterase. (1112 aa)
ZNF449Zinc finger protein 449. (369 aa)
TMEM254Transmembrane protein 254 isoform X1. (129 aa)
SH3GLB2endophilin-B2 isoform X1. (404 aa)
LOC101384189Cytochrome c oxidase subunit 7A1, mitochondrial. (80 aa)
FAM45AProtein FAM45A isoform X1. (399 aa)
LOC101364305Uncharacterized protein C1orf54 homolog isoform X1. (132 aa)
DAD1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (113 aa)
CD300LGCMRF35-like molecule 9. (368 aa)
ANO6Anoctamin. (929 aa)
LOC101375928Zinc finger protein 449. (344 aa)
KIF16BKinesin-like protein KIF16B isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1397 aa)
ACACBacetyl-CoA carboxylase 2. (2456 aa)
THAP1THAP domain-containing protein 1. (213 aa)
SMAP2Stromal membrane-associated protein 2 isoform X1. (429 aa)
ADIGAdipogenin. (73 aa)
ARMCX6Protein ARMCX6. (300 aa)
EMG1Ribosomal RNA small subunit methyltransferase NEP1. (244 aa)
ROBO4Roundabout homolog 4. (1004 aa)
ADIPOQAdiponectin isoform X1. (266 aa)
MRPL1739S ribosomal protein L17, mitochondrial; Belongs to the bacterial ribosomal protein bL17 family. (200 aa)
PRIMPOLDNA-directed primase/polymerase protein isoform X1. (557 aa)
RETNResistin. (110 aa)
ANGPTL4Angiopoietin-related protein 4 isoform X1. (412 aa)
PNPLA8Calcium-independent phospholipase A2-gamma isoform X1. (781 aa)
MANFMesencephalic astrocyte-derived neurotrophic factor. (179 aa)
SMIM4Small integral membrane protein 4. (80 aa)
DNLZDNL-type zinc finger protein. (171 aa)
ADIRFAdipogenesis regulatory factor. (75 aa)
LDB3LIM domain-binding protein 3 isoform X1. (725 aa)
ACPTTesticular acid phosphatase; Belongs to the histidine acid phosphatase family. (426 aa)
RRASRas-related protein R-Ras. (218 aa)
LOC101373381Bombesin receptor-activated protein C6orf89 homolog isoform X1. (387 aa)
GALNT15Polypeptide N-acetylgalactosaminyltransferase. (634 aa)
CNEP1R1Nuclear envelope phosphatase-regulatory subunit 1. (125 aa)
LIPEHormone-sensitive lipase. (762 aa)
ICE2Little elongation complex subunit 2 isoform X1. (981 aa)
TMEM41ATransmembrane protein 41A. (264 aa)
ASB14Ankyrin repeat and SOCS box protein 14. (587 aa)
FABP3Fatty acid-binding protein, heart; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa)
MRPS628S ribosomal protein S6, mitochondrial. (115 aa)
UCP1Mitochondrial brown fat uncoupling protein 1 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
VCANVersican core protein isoform X1. (3400 aa)
ABCC9ATP-binding cassette sub-family C member 9 isoform X2. (1549 aa)
CEBPACCAAT/enhancer-binding protein alpha. (354 aa)
EPN2Epsin-2 isoform X1. (641 aa)
MCUR1Mitochondrial calcium uniporter regulator 1. (389 aa)
TUSC5Tumor suppressor candidate 5. (230 aa)
TIMM22Mitochondrial import inner membrane translocase subunit Tim22. (194 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
PNPLA2Patatin-like phospholipase domain-containing protein 2. (486 aa)
GZMKGranzyme K; Belongs to the peptidase S1 family. (268 aa)
EVA1BProtein eva-1 homolog B. (166 aa)
METTL17Methyltransferase-like protein 17, mitochondrial isoform X2. (468 aa)
SCDacyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (359 aa)
MKNK1MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1; Belongs to the protein kinase superfamily. (421 aa)
SCARF2Scavenger receptor class F member 2 isoform X1. (870 aa)
LOC101383672Cytochrome c oxidase protein 20 homolog. (119 aa)
YIPF1Protein YIPF. (303 aa)
MRPL3039S ribosomal protein L30, mitochondrial. (161 aa)
ACP2Lysosomal acid phosphatase isoform X1; Belongs to the histidine acid phosphatase family. (423 aa)
BOLA3bolA-like protein 3 isoform X1; Belongs to the BolA/IbaG family. (110 aa)
SLC2A4Solute carrier family 2, facilitated glucose transporter member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (508 aa)
LOC101380962Uncharacterized protein C17orf59 homolog. (355 aa)
PLIN1Perilipin; Belongs to the perilipin family. (516 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
ACACAacetyl-CoA carboxylase 1 isoform X1. (2385 aa)
SERHL2Serine hydrolase-like protein 2. (309 aa)
LOC101375046Cytochrome c oxidase subunit 7A1, mitochondrial. (80 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (529 aa)
TPRA1Transmembrane protein adipocyte-associated 1. (367 aa)
CFDComplement factor D; Belongs to the peptidase S1 family. (259 aa)
RPS1540S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family. (145 aa)
RSAD1Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (442 aa)
C3Complement C3. (1661 aa)
COPZ2Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (210 aa)
MRPL4539S ribosomal protein L45, mitochondrial isoform X1. (329 aa)
ADRB3Beta-3 adrenergic receptor. (408 aa)
ICT1peptidyl-tRNA hydrolase ICT1, mitochondrial. (206 aa)
PELI3E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (468 aa)
FABP4Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
RSU1Ras suppressor protein 1 isoform X1. (277 aa)
ENGEndoglin. (659 aa)
SLC25A51Solute carrier family 25 member 51; Belongs to the mitochondrial carrier (TC 2.A.29) family. (297 aa)
CREBRFCREB3 regulatory factor. (639 aa)
UCP2Mitochondrial uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa)
UCP3Mitochondrial uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (311 aa)
RETNLBResistin-like beta. (109 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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