STRINGSTRING
RAD21 RAD21 BUB1 BUB1 BAZ1A BAZ1A DYNLT3 DYNLT3 SPAG5 SPAG5 CKAP5 CKAP5 ZNF207 ZNF207 NUP160 NUP160 LRWD1 LRWD1 SPC24 SPC24 DNMT1 DNMT1 PLK1 PLK1 DCTN1 DCTN1 MIS12 MIS12 NDEL1 NDEL1 RASSF2 RASSF2 CENPB CENPB SGOL1 SGOL1 KAT2B KAT2B SKA2 SKA2 XPO1 XPO1 SMC5 SMC5 CENPM CENPM KAT8 KAT8 CBX3 CBX3 RCC2 RCC2 SPC25 SPC25 ZNF618 ZNF618 SUV39H1 SUV39H1 KNTC1 KNTC1 PPP1CC PPP1CC SIRT6 SIRT6 PINX1 PINX1 TOP2A TOP2A CBX1 CBX1 CENPO CENPO GALK1 GALK1 MAD1L1 MAD1L1 SUV420H1 SUV420H1 CHMP4C CHMP4C PSEN2 PSEN2 CENPP CENPP PHF2 PHF2 FBXO28 FBXO28 SGOL2 SGOL2 ORC2 ORC2 CENPT CENPT DSN1 DSN1 CENPC CENPC SEC13 SEC13 LOC101382075 LOC101382075 DCTN3 DCTN3 CHMP5 CHMP5 CDT1 CDT1 ZNF276 ZNF276 CHMP1A CHMP1A FBXW11 FBXW11 BOD1 BOD1 NUP98 NUP98 CHAMP1 CHAMP1 DSCC1 DSCC1 MTBP MTBP CEBPB CEBPB SNAI1 SNAI1 HELLS HELLS SEPT2 SEPT2 ANAPC16 ANAPC16 NUP37 NUP37 ITGB3BP ITGB3BP CHMP2B CHMP2B FMR1 FMR1 NCAPD2 NCAPD2 CENPQ CENPQ NSL1 NSL1 ZWILCH ZWILCH DYNC1LI1 DYNC1LI1 MIS18BP1 MIS18BP1 IKZF1 IKZF1 LOC101366939 LOC101366939 CHMP3 CHMP3 CENPF CENPF SMC1B SMC1B NCAPD3 NCAPD3 BIRC5 BIRC5 BUB3 BUB3 ZW10 ZW10 SEPT7 SEPT7 KIF2B KIF2B SYCP3 SYCP3 CENPI CENPI NEK2 NEK2 LOC101378834 LOC101378834 CENPV CENPV LOC101379460 LOC101379460 NUP85 NUP85 LOC101367193 LOC101367193 LOC101369391 LOC101369391 KDM4B KDM4B LOC101386760 LOC101386760 HJURP HJURP FAM193A FAM193A RANGAP1 RANGAP1 SPDL1 SPDL1 AURKB AURKB BAZ1B BAZ1B HSF1 HSF1 PHF6 PHF6 CHMP4A CHMP4A REC8 REC8 CHMP7 CHMP7 SKA3 SKA3 LOC101373553 LOC101373553 NUP43 NUP43 LOC101371799 LOC101371799 CHMP2A CHMP2A SEPT6 SEPT6 LOC101373737 LOC101373737 ZNF330 ZNF330 MEIKIN MEIKIN CLASP2 CLASP2 SUV39H2 SUV39H2 NDC80 NDC80 ESCO2 ESCO2 CENPU CENPU ERCC6L ERCC6L KAT5 KAT5 AFMID AFMID LOC101370493 LOC101370493 RASSF4 RASSF4 CHMP1B CHMP1B GPATCH11 GPATCH11 INCENP INCENP DYNC1I1 DYNC1I1 NCAPG NCAPG SKA1 SKA1 BOD1L1 BOD1L1 LOC101386320 LOC101386320 TP53BP1 TP53BP1 ATRX ATRX SMC3 SMC3 LOC101364017 LOC101364017 TPR TPR NUP107 NUP107 SMC4 SMC4 CBX5 CBX5 MIS18A MIS18A SMC1A SMC1A SMARCA5 SMARCA5 SMC6 SMC6 DAXX DAXX SIN3A SIN3A PPP2CB PPP2CB DCTN6 DCTN6 SEH1L SEH1L KIF18A KIF18A EZH2 EZH2 NDE1 NDE1 CENPL CENPL ZWINT ZWINT CHRAC1 CHRAC1 LOC101381952 LOC101381952 PPP2CA PPP2CA SUV420H2 SUV420H2 TRAPPC12 TRAPPC12 NUP133 NUP133 CLASP1 CLASP1 CHMP6 CHMP6 STRA13 STRA13 PAFAH1B1 PAFAH1B1 CENPW CENPW NUF2 NUF2 CENPH CENPH LOC101382439 LOC101382439 MEAF6 MEAF6 CDCA8 CDCA8 CENPK CENPK NGDN NGDN MDP1 MDP1 CENPE CENPE DCTN2 DCTN2 MAD2L1 MAD2L1 APC APC KIF2C KIF2C KDM4A KDM4A HNRNPU HNRNPU BUB1B BUB1B CASC5 CASC5 AHCTF1 AHCTF1 KNSTRN KNSTRN OIP5 OIP5 TTK TTK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAD21Double-strand-break repair protein rad21 homolog. (402 aa)
BUB1Mitotic checkpoint serine/threonine-protein kinase BUB1 isoform X1. (1086 aa)
BAZ1ABromodomain adjacent to zinc finger domain protein 1A isoform X2. (1557 aa)
DYNLT3Dynein light chain Tctex-type 3. (259 aa)
SPAG5Sperm-associated antigen 5. (1196 aa)
CKAP5Cytoskeleton-associated protein 5. (2033 aa)
ZNF207BUB3-interacting and GLEBS motif-containing protein ZNF207 isoform X1. (494 aa)
NUP160Nuclear pore complex protein Nup160. (1402 aa)
LRWD1Leucine-rich repeat and WD repeat-containing protein 1. (649 aa)
SPC24Kinetochore protein Spc24. (197 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1649 aa)
PLK1Serine/threonine-protein kinase PLK. (604 aa)
DCTN1Dynactin subunit 1 isoform X1. (1281 aa)
MIS12Protein MIS12 homolog. (206 aa)
NDEL1Nuclear distribution protein nudE-like 1 isoform X1. (345 aa)
RASSF2Ras association domain-containing protein 2. (326 aa)
CENPBMajor centromere autoantigen B. (493 aa)
SGOL1Shugoshin-like 1 isoform X1. (525 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (832 aa)
SKA2Spindle and kinetochore-associated protein 2. (121 aa)
XPO1Exportin-1. (1071 aa)
SMC5Structural maintenance of chromosomes protein 5. (1107 aa)
CENPMCentromere protein M isoform X1. (180 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (458 aa)
CBX3Chromobox protein homolog 3. (183 aa)
RCC2Protein RCC2. (522 aa)
SPC25Kinetochore protein Spc25. (226 aa)
ZNF618Zinc finger protein 618 isoform X1. (954 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (412 aa)
KNTC1Kinetochore-associated protein 1. (2207 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6. (359 aa)
PINX1PIN2/TERF1-interacting telomerase inhibitor 1. (316 aa)
TOP2ADNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1534 aa)
CBX1Chromobox protein homolog 1. (185 aa)
CENPOCentromere protein O. (296 aa)
GALK1Galactokinase. (392 aa)
MAD1L1Mitotic spindle assembly checkpoint protein MAD1 isoform X1. (717 aa)
SUV420H1Histone-lysine N-methyltransferase SUV420H1 isoform X1. (935 aa)
CHMP4CCharged multivesicular body protein 4c. (236 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (464 aa)
CENPPCentromere protein P. (288 aa)
PHF2Lysine-specific demethylase PHF2. (1380 aa)
FBXO28F-box only protein 28 isoform X1. (368 aa)
SGOL2LOW QUALITY PROTEIN: shugoshin-like 2. (1256 aa)
ORC2Origin recognition complex subunit 2. (578 aa)
CENPTCentromere protein T. (557 aa)
DSN1Kinetochore-associated protein DSN1 homolog isoform X1. (356 aa)
CENPCLOW QUALITY PROTEIN: centromere protein C. (950 aa)
SEC13Protein SEC13 homolog isoform X1; Belongs to the WD repeat SEC13 family. (322 aa)
LOC101382075Putative methyltransferase C9orf114 homolog. (375 aa)
DCTN3Dynactin subunit 3 isoform X1. (186 aa)
CHMP5Charged multivesicular body protein 5. (219 aa)
CDT1DNA replication factor Cdt1. (619 aa)
ZNF276Zinc finger protein 276. (604 aa)
CHMP1ACharged multivesicular body protein 1a. (196 aa)
FBXW11F-box/WD repeat-containing protein 11 isoform X1. (542 aa)
BOD1Biorientation of chromosomes in cell division protein 1. (266 aa)
NUP98Nuclear pore complex protein Nup98-Nup96 isoform X1. (1800 aa)
CHAMP1Chromosome alignment-maintaining phosphoprotein 1. (816 aa)
DSCC1Sister chromatid cohesion protein DCC1. (392 aa)
MTBPMdm2-binding protein. (904 aa)
CEBPBCCAAT/enhancer-binding protein. (348 aa)
SNAI1Zinc finger protein SNAI1. (264 aa)
HELLSLymphoid-specific helicase isoform X1. (837 aa)
SEPT2Septin-2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (361 aa)
ANAPC16Anaphase-promoting complex subunit 16 isoform X1. (110 aa)
NUP37Nucleoporin Nup37 isoform X1. (326 aa)
ITGB3BPCentromere protein R. (138 aa)
CHMP2BCharged multivesicular body protein 2b isoform X1. (213 aa)
FMR1Fragile X mental retardation protein 1 isoform X1. (632 aa)
NCAPD2Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1399 aa)
CENPQCentromere protein Q isoform X1. (268 aa)
NSL1Kinetochore-associated protein NSL1 homolog isoform X1. (280 aa)
ZWILCHProtein zwilch homolog isoform X1. (589 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (524 aa)
MIS18BP1Mis18-binding protein 1. (1140 aa)
IKZF1DNA-binding protein Ikaros isoform X1. (519 aa)
LOC101366939Transcriptional regulator ATRX-like. (259 aa)
CHMP3Charged multivesicular body protein 3 isoform X1. (223 aa)
CENPFCentromere protein F. (3112 aa)
SMC1BStructural maintenance of chromosomes protein. (1235 aa)
NCAPD3Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1498 aa)
BIRC5Baculoviral IAP repeat-containing protein 5. (142 aa)
BUB3Mitotic checkpoint protein BUB3 isoform X1. (328 aa)
ZW10Centromere/kinetochore protein zw10 homolog. (779 aa)
SEPT7Septin-7 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (437 aa)
KIF2BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (683 aa)
SYCP3Synaptonemal complex protein 3 isoform X1. (242 aa)
CENPICentromere protein I. (743 aa)
NEK2Serine/threonine-protein kinase Nek2. (444 aa)
LOC101378834Double-strand-break repair protein rad21 homolog. (152 aa)
CENPVLOW QUALITY PROTEIN: centromere protein V. (262 aa)
LOC101379460LOW QUALITY PROTEIN: small kinetochore-associated protein-like. (284 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (514 aa)
LOC101367193LOW QUALITY PROTEIN: kinetochore protein Spc25-like. (233 aa)
LOC101369391Inactive serine/threonine-protein kinase TEX14-like. (703 aa)
KDM4BLysine-specific demethylase 4B. (1124 aa)
LOC101386760Shugoshin-like 1. (319 aa)
HJURPLOW QUALITY PROTEIN: Holliday junction recognition protein. (818 aa)
FAM193AProtein FAM193A isoform X1. (1431 aa)
RANGAP1Ran GTPase-activating protein 1. (619 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (620 aa)
AURKBAurora kinase B isoform X1; Belongs to the protein kinase superfamily. (354 aa)
BAZ1BTyrosine-protein kinase BAZ1B. (1481 aa)
HSF1Heat shock factor protein 1 isoform X1. (555 aa)
PHF6PHD finger protein 6 isoform X1. (366 aa)
CHMP4ACharged multivesicular body protein 4a. (220 aa)
REC8Meiotic recombination protein REC8 homolog. (593 aa)
CHMP7Charged multivesicular body protein 7 isoform X1. (455 aa)
SKA3Spindle and kinetochore-associated protein 3 isoform X1. (413 aa)
LOC101373553LOW QUALITY PROTEIN: double-strand-break repair protein rad21 homolog. (625 aa)
NUP43Nucleoporin Nup43. (380 aa)
LOC101371799Spindle and kinetochore-associated protein 2-like. (111 aa)
CHMP2ACharged multivesicular body protein 2a isoform X1. (252 aa)
SEPT6Septin-6 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (466 aa)
LOC101373737Centromere protein P-like. (247 aa)
ZNF330Zinc finger protein 330 isoform X1. (338 aa)
MEIKINMeiosis-specific kinetochore protein. (481 aa)
CLASP2CLIP-associating protein 2 isoform X1. (1527 aa)
SUV39H2Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (544 aa)
NDC80Kinetochore protein NDC80 homolog isoform X1. (696 aa)
ESCO2N-acetyltransferase ESCO2. (614 aa)
CENPUCentromere protein U. (442 aa)
ERCC6LDNA excision repair protein ERCC-6-like. (1246 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (555 aa)
AFMIDKynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (261 aa)
LOC101370493Centromere protein V-like. (139 aa)
RASSF4Ras association domain-containing protein 4. (321 aa)
CHMP1BCharged multivesicular body protein 1b. (199 aa)
GPATCH11G patch domain-containing protein 11. (264 aa)
INCENPInner centromere protein. (858 aa)
DYNC1I1Cytoplasmic dynein 1 intermediate chain 1 isoform X1. (645 aa)
NCAPGCondensin complex subunit 3. (1012 aa)
SKA1Spindle and kinetochore-associated protein 1. (255 aa)
BOD1L1Biorientation of chromosomes in cell division protein 1-like 1. (3042 aa)
LOC101386320Centromere protein S. (165 aa)
TP53BP1Tumor suppressor p53-binding protein 1. (1975 aa)
ATRXTranscriptional regulator ATRX. (2226 aa)
SMC3Structural maintenance of chromosomes protein. (1217 aa)
LOC101364017Dynein light chain Tctex-type 3. (153 aa)
TPRNucleoprotein TPR. (2439 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa)
SMC4Structural maintenance of chromosomes protein. (1287 aa)
CBX5Chromobox protein homolog 5. (191 aa)
MIS18AProtein Mis18-alpha. (237 aa)
SMC1AStructural maintenance of chromosomes protein. (1233 aa)
SMARCA5SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5. (1052 aa)
SMC6Structural maintenance of chromosomes protein 6. (1097 aa)
DAXXDeath domain-associated protein 6 isoform X1. (757 aa)
SIN3APaired amphipathic helix protein Sin3a. (1274 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
DCTN6Dynactin subunit 6. (190 aa)
SEH1LNucleoporin SEH1 isoform X1; Belongs to the WD repeat SEC13 family. (421 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (898 aa)
EZH2Histone-lysine N-methyltransferase EZH2 isoform X1. (751 aa)
NDE1Nuclear distribution protein nudE homolog 1. (346 aa)
CENPLCentromere protein L. (346 aa)
ZWINTLOW QUALITY PROTEIN: ZW10 interactor. (516 aa)
CHRAC1Chromatin accessibility complex protein 1. (129 aa)
LOC101381952Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
SUV420H2Histone-lysine N-methyltransferase SUV420H2. (461 aa)
TRAPPC12Trafficking protein particle complex subunit 12. (786 aa)
NUP133Nuclear pore complex protein Nup133. (1156 aa)
CLASP1CLIP-associating protein 1 isoform X1. (1539 aa)
CHMP6Charged multivesicular body protein 6. (201 aa)
STRA13Centromere protein X. (79 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
CENPWCentromere protein W. (88 aa)
NUF2Kinetochore protein Nuf2. (464 aa)
CENPHCentromere protein H. (247 aa)
LOC101382439Polyamine-modulated factor 1. (205 aa)
MEAF6Chromatin modification-related protein MEAF6 isoform X1. (201 aa)
CDCA8Borealin. (280 aa)
CENPKCentromere protein K. (273 aa)
NGDNNeuroguidin. (318 aa)
MDP1Magnesium-dependent phosphatase 1. (164 aa)
CENPELOW QUALITY PROTEIN: centromere-associated protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2678 aa)
DCTN2Dynactin subunit 2 isoform X1. (408 aa)
MAD2L1Mitotic spindle assembly checkpoint protein MAD2A. (205 aa)
APCAdenomatous polyposis coli protein isoform X1. (2844 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (723 aa)
KDM4ALysine-specific demethylase 4A. (1066 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U isoform X1. (825 aa)
BUB1BMitotic checkpoint serine/threonine-protein kinase BUB1 beta. (1062 aa)
CASC5Protein CASC5. (2352 aa)
AHCTF1Protein ELYS. (2245 aa)
KNSTRNSmall kinetochore-associated protein. (275 aa)
OIP5Protein Mis18-beta. (229 aa)
TTKDual specificity protein kinase TTK isoform X1. (855 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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