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BMPR2 BMPR2 BMP4 BMP4 CDH13 CDH13 ITGA4 ITGA4 ZNF580 ZNF580 VEGFA VEGFA APELA APELA AGGF1 AGGF1 FGF2 FGF2 NRAS NRAS PRKD2 PRKD2 TGFBR1 TGFBR1 PDGFB PDGFB FGF7 FGF7 IL10 IL10 NRARP NRARP GDF2 GDF2 BMP2 BMP2 HMOX1 HMOX1 FGF10 FGF10 PRKCA PRKCA PROX1 PROX1 LOC101367134 LOC101367134 JUN JUN VASH2 VASH2 RNASE4 RNASE4 VIP VIP FLT4 FLT4 LOC101371244 LOC101371244 LOC101382658 LOC101382658 PDCD6 PDCD6 ITGB3 ITGB3 EGFL7 EGFL7 STAT3 STAT3 STAT5A STAT5A EMC10 EMC10 APLNR APLNR SCG2 SCG2 PROK1 PROK1 HMGB1 HMGB1 VEGFC VEGFC SP1 SP1 BMP6 BMP6 THBS4 THBS4 ECM1 ECM1 HRAS HRAS PDPK1 PDPK1 F3 F3 EGR3 EGR3 KIAA1462 KIAA1462 ACVRL1 ACVRL1 AKT3 AKT3 PDCL3 PDCL3 PRKD1 PRKD1 NF1 NF1 PGF PGF CCL24 CCL24 CCR5 CCR5 CCL26 CCL26 PIK3CD PIK3CD AKT2 AKT2 KDR KDR HTR2B HTR2B AKT1 AKT1 SIRT6 SIRT6 MYDGF MYDGF LRG1 LRG1 VEGFB VEGFB SIRT1 SIRT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
CDH13Cadherin-13 isoform X1. (713 aa)
ITGA4Integrin alpha-4; Belongs to the integrin alpha chain family. (1033 aa)
ZNF580LOW QUALITY PROTEIN: zinc finger protein 580. (494 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (587 aa)
APELAApelin receptor early endogenous ligand. (54 aa)
AGGF1Angiogenic factor with G patch and FHA domains 1. (716 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (377 aa)
NRASGTPase NRas. (189 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (877 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
PDGFBPlatelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (242 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
IL10Interleukin-10. (178 aa)
NRARPNotch-regulated ankyrin repeat-containing protein. (114 aa)
GDF2Growth/differentiation factor 2. (428 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
HMOX1Heme oxygenase 1. (322 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
PROX1Prospero homeobox protein 1. (737 aa)
LOC101367134GTPase HRas-like. (177 aa)
JUNTranscription factor AP-1 isoform X1; Belongs to the bZIP family. (335 aa)
VASH2Vasohibin-2. (355 aa)
RNASE4Ribonuclease 4; Belongs to the pancreatic ribonuclease family. (146 aa)
VIPVIP peptides isoform X1. (170 aa)
FLT4Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1450 aa)
LOC101371244C-C motif chemokine. (93 aa)
LOC101382658Programmed cell death protein 6-like isoform X1. (189 aa)
PDCD6Programmed cell death protein 6 isoform X1. (189 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
EGFL7Epidermal growth factor-like protein 7. (274 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
EMC10ER membrane protein complex subunit 10 isoform X1. (262 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
SCG2Secretogranin-2. (618 aa)
PROK1Prokineticin-1. (105 aa)
HMGB1High mobility group protein B1. (207 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (421 aa)
SP1Transcription factor Sp1 isoform X1. (786 aa)
BMP6Bone morphogenetic protein 6. (505 aa)
THBS4Thrombospondin-4 isoform X1. (961 aa)
ECM1Extracellular matrix protein 1 isoform X1. (542 aa)
HRASGTPase HRas isoform X1. (189 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
F3Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (288 aa)
EGR3Early growth response protein 3 isoform X1. (387 aa)
KIAA1462Junctional protein associated with coronary artery disease. (1365 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (523 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PDCL3Phosducin-like protein 3. (240 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (912 aa)
NF1Neurofibromin isoform X1. (2841 aa)
PGFPlacenta growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa)
CCL24C-C motif chemokine 24. (119 aa)
CCR5C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (352 aa)
CCL26C-C motif chemokine. (94 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
HTR2B5-hydroxytryptamine receptor 2B. (480 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6. (359 aa)
MYDGFLOW QUALITY PROTEIN: myeloid-derived growth factor. (276 aa)
LRG1Leucine-rich alpha-2-glycoprotein. (354 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (188 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (740 aa)
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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